ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin AA Goodarzi, AT Noon, D Deckbar, Y Ziv, Y Shiloh, M Löbrich, PA Jeggo Molecular cell 31 (2), 167-177, 2008 | 1031 | 2008 |
γH2AX foci analysis for monitoring DNA double-strand break repair: strengths, limitations and optimization M Löbrich, A Shibata, A Beucher, A Fisher, M Ensminger, AA Goodarzi, ... Cell cycle 9 (4), 662-669, 2010 | 794 | 2010 |
ATM and Artemis promote homologous recombination of radiation‐induced DNA double‐strand breaks in G2 A Beucher, J Birraux, L Tchouandong, O Barton, A Shibata, S Conrad, ... The EMBO journal 28 (21), 3413-3427, 2009 | 682 | 2009 |
ATR‐dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling T Stiff, SA Walker, K Cerosaletti, AA Goodarzi, E Petermann, ... The EMBO journal 25 (24), 5775-5782, 2006 | 469 | 2006 |
DNA‐PK autophosphorylation facilitates Artemis endonuclease activity AA Goodarzi, Y Yu, E Riballo, P Douglas, SA Walker, R Ye, C Härer, ... The EMBO journal 25 (16), 3880-3889, 2006 | 468 | 2006 |
ATM Mediates Phosphorylation at Multiple p53 Sites, Including Ser46, in Response to Ionizing Radiation∗ S Saito, AA Goodarzi, Y Higashimoto, Y Noda, SP Lees-Miller, E Appella, ... Journal of Biological Chemistry 277 (15), 12491-12494, 2002 | 422 | 2002 |
53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair AT Noon, A Shibata, N Rief, M Löbrich, GS Stewart, PA Jeggo, ... Nature cell biology 12 (2), 177-184, 2010 | 404 | 2010 |
The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax AA Goodarzi, P Jeggo, M Lobrich DNA repair 9 (12), 1273-1282, 2010 | 380 | 2010 |
Autophosphorylation of ataxia‐telangiectasia mutated is regulated by protein phosphatase 2A AA Goodarzi, JC Jonnalagadda, P Douglas, D Young, R Ye, ... The EMBO journal 23 (22), 4451-4461, 2004 | 334 | 2004 |
KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response AA Goodarzi, T Kurka, PA Jeggo Nature structural & molecular biology 18 (7), 831-839, 2011 | 290 | 2011 |
The repair and signaling responses to DNA double-strand breaks AA Goodarzi, PA Jeggo Advances in genetics 82, 1-45, 2013 | 267 | 2013 |
Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase P Douglas, GP Sapkota, N Morrice, Y Yu, AA Goodarzi, D Merkle, K Meek, ... Biochemical Journal 368 (1), 243-251, 2002 | 252 | 2002 |
The impact of heterochromatin on DSB repair AA Goodarzi, AT Noon, PA Jeggo Biochemical Society Transactions 37 (3), 569-576, 2009 | 186 | 2009 |
53BP1 promotes ATM activity through direct interactions with the MRN complex JH Lee, AA Goodarzi, PA Jeggo, TT Paull The EMBO journal 29 (3), 574-585, 2010 | 180 | 2010 |
Inhibition of the G2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine D Curman, B Cinel, DE Williams, N Rundle, WD Block, AA Goodarzi, ... Journal of Biological Chemistry 276 (21), 17914-17919, 2001 | 166 | 2001 |
Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair L Woodbine, H Brunton, AA Goodarzi, A Shibata, PA Jeggo Nucleic acids research 39 (16), 6986-6997, 2011 | 161 | 2011 |
Purification and characterization of ATM from human placenta: a manganese-dependent, wortmannin-sensitive serine/threonine protein kinase DW Chan, SC Son, W Block, R Ye, KK Khanna, MS Wold, P Douglas, ... Journal of Biological Chemistry 275 (11), 7803-7810, 2000 | 159 | 2000 |
Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366 GP Sapkota, M Deak, A Kieloch, N Morrice, AA Goodarzi, C Smythe, ... Biochemical Journal 368 (2), 507-516, 2002 | 155 | 2002 |
XLF-Cernunnos promotes DNA ligase IV–XRCC4 re-adenylation following ligation E Riballo, L Woodbine, T Stiff, SA Walker, AA Goodarzi, PA Jeggo Nucleic acids research 37 (2), 482-492, 2009 | 154 | 2009 |
Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G2/M checkpoint arrest A Shibata, O Barton, AT Noon, K Dahm, D Deckbar, AA Goodarzi, ... Molecular and cellular biology, 2010 | 149 | 2010 |