Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer SA Eccles, EO Aboagye, S Ali, AS Anderson, J Armes, F Berditchevski, ... Breast Cancer Research 15, 1-37, 2013 | 518 | 2013 |
Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (DEPICT-1): 24 week results from a multicentre, double-blind, phase 3, randomised … P Dandona, C Mathieu, M Phillip, L Hansen, SC Griffen, D Tschöpe, ... The lancet Diabetes & endocrinology 5 (11), 864-876, 2017 | 310 | 2017 |
The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression L Qin, L Liao, A Redmond, L Young, Y Yuan, H Chen, BW O'Malley, J Xu Molecular and cellular biology 28 (19), 5937-5950, 2008 | 222 | 2008 |
Associations and interactions between Ets-1 and Ets-2 and coregulatory proteins, SRC-1, AIB1, and NCoR in breast cancer E Myers, ADK Hill, G Kelly, EW McDermott, NJ O'Higgins, Y Buggy, ... Clinical Cancer Research 11 (6), 2111-2122, 2005 | 172 | 2005 |
Intrinsic Subtype Switching and Acquired ERBB2/HER2 Amplifications and Mutations in Breast Cancer Brain Metastases. LAV Priedigkeit N, Hartmaier RJ, Chen Y, Vareslija D, Basudan A, Watters RJ ... JAMA Oncology 3 (5), 666-671, 2017 | 168 | 2017 |
Expression of SRC-1, AIB1, and PEA3 in HER2 mediated endocrine resistant breast cancer; a predictive role for SRC-1 FJ Fleming, E Myers, G Kelly, TB Crotty, EW McDermott, NJ O’higgins, ... Journal of clinical pathology 57 (10), 1069-1074, 2004 | 166 | 2004 |
Inverse relationship between ER-β and SRC-1 predicts outcome in endocrine-resistant breast cancer E Myers, FJ Fleming, TB Crotty, G Kelly, EW McDermott, NJ O'higgins, ... British journal of cancer 91 (9), 1687-1693, 2004 | 152 | 2004 |
Differential recruitment of coregulator proteins steroid receptor coactivator-1 and silencing mediator for retinoid and thyroid receptors to the estrogen receptor-estrogen … FJ Fleming, ADK Hill, EW McDermott, NJ O’Higgins, LS Young The Journal of Clinical Endocrinology & Metabolism 89 (1), 375-383, 2004 | 128 | 2004 |
The function of steroid receptor coactivator-1 in normal tissues and cancer CA Walsh, L Qin, JCY Tien, LS Young, J Xu International journal of biological sciences 8 (4), 470, 2012 | 125 | 2012 |
CD44 increases the efficiency of distant metastasis of breast cancer S McFarlane, JA Coulter, P Tibbits, A O'Grady, C McFarlane, ... Oncotarget 6 (13), 11465, 2015 | 123 | 2015 |
Epigenetic reprogramming of HOXC10 in endocrine-resistant breast cancer. OS Pathiraja TN1, Nayak SR, Xi Y, Jiang S, Garee JP, Edwards DP, Lee AV ... Science Translational Medicine. 6 (229), 229ra41, 2014 | 117 | 2014 |
Coassociation of estrogen receptor and p160 proteins predicts resistance to endocrine treatment; SRC-1 is an independent predictor of breast cancer recurrence AM Redmond, FT Bane, AT Stafford, M McIlroy, MF Dillon, TB Crotty, ... Clinical Cancer Research 15 (6), 2098-2106, 2009 | 111 | 2009 |
Transcriptome characterization of matched primary breast and brain metastatic tumors to detect novel actionable targets D Varešlija, N Priedigkeit, A Fagan, S Purcell, N Cosgrove, PJ O’Halloran, ... JNCI: Journal of the National Cancer Institute 111 (4), 388-398, 2019 | 100 | 2019 |
Nitric oxide in early ischaemia reperfusion injury during human orthotopic liver transplantation R Varadarajan, L Golden-Mason, L Young, P McLoughlin, N Nolan, ... Transplantation 78 (2), 250-256, 2004 | 92 | 2004 |
Growth factor-dependent regulation of survivin by c-myc in human breast cancer N Cosgrave, ADK Hill, LS Young Journal of molecular endocrinology 37 (3), 377-390, 2006 | 89 | 2006 |
Nitric oxide in unilateral ureteral obstruction: effect on regional renal blood flow NJ Hegarty, LS Young, CN Kirwan, AJ O'Neill, DM Bouchier-Hayes, ... Kidney international 59 (3), 1059-1065, 2001 | 89 | 2001 |
Metastatic progression with resistance to aromatase inhibitors is driven by the steroid receptor coactivator SRC-1 J McBryan, SM Theissen, C Byrne, E Hughes, S Cocchiglia, S Sande, ... Cancer research 72 (2), 548-559, 2012 | 82 | 2012 |
Interaction of developmental transcription factor HOXC11 with steroid receptor coactivator SRC-1 mediates resistance to endocrine therapy in breast cancer M McIlroy, D McCartan, S Early, PO Gaora, S Pennington, ADK Hill, ... Cancer research 70 (4), 1585-1594, 2010 | 78 | 2010 |
Review of effects of water pollution on the breeding success of waterbirds, with particular reference to ardeids in Hong Kong SB De Luca-Abbott, BSF Wong, DB Peakall, PKS Lam, L Young, ... Ecotoxicology 10, 327-349, 2001 | 78 | 2001 |
The LIM domain protein LPP is a coactivator for the ETS domain transcription factor PEA3 B Guo, RE Sallis, A Greenall, MMR Petit, E Jansen, L Young, ... Molecular and cellular biology, 2006 | 76 | 2006 |