Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways MC Boelens, TJ Wu, BY Nabet, B Xu, Y Qiu, T Yoon, DJ Azzam, ... Cell 159 (3), 499-513, 2014 | 831 | 2014 |
VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2 D Zhao, C Pan, J Sun, C Gilbert, K Drews-Elger, DJ Azzam, M Picon-Ruiz, ... Oncogene 34 (24), 3107-3119, 2015 | 282 | 2015 |
Interactions between adipocytes and breast cancer cells stimulate cytokine production and drive Src/Sox2/miR-302b–mediated malignant progression M Picon-Ruiz, C Pan, K Drews-Elger, K Jang, AH Besser, D Zhao, ... Cancer research 76 (2), 491-504, 2016 | 186 | 2016 |
Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer AE Witt, CW Lee, TI Lee, DJ Azzam, B Wang, C Caslini, F Petrocca, ... Oncogene 36 (12), 1707-1720, 2017 | 162 | 2017 |
Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ‐secretase inhibitor drug responses DJ Azzam, D Zhao, J Sun, AJ Minn, P Ranganathan, K Drews‐Elger, ... EMBO molecular medicine 5 (10), 1502-1522, 2013 | 85 | 2013 |
Dual Src and MEK inhibition decreases ovarian cancer growth and targets tumor initiating stem-like cells F Simpkins, K Jang, H Yoon, KE Hew, M Kim, DJ Azzam, J Sun, D Zhao, ... Clinical cancer research 24 (19), 4874-4886, 2018 | 71 | 2018 |
Combined Src and ER blockade impairs human breast cancer proliferation in vitro and in vivo Y Chen, EA Alvarez, D Azzam, SA Wander, N Guggisberg, M Jordà, Z Ju, ... Breast cancer research and treatment 128, 69-78, 2011 | 68 | 2011 |
Src Inhibition with Saracatinib Reverses Fulvestrant Resistance in ER-Positive Ovarian Cancer Models In Vitro and In Vivo F Simpkins, P Hevia-Paez, J Sun, W Ullmer, CA Gilbert, T Da Silva, ... Clinical cancer research 18 (21), 5911-5923, 2012 | 63 | 2012 |
Imaging neuroinflammation with TSPO: A new perspective on the cellular sources and subcellular localization TR Guilarte, AN Rodichkin, JL McGlothan, AMA De La Rocha, DJ Azzam Pharmacology & therapeutics 234, 108048, 2022 | 59 | 2022 |
Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study RT Swords, D Azzam, H Al-Ali, I Lohse, CH Volmar, JM Watts, A Perez, ... Leukemia Research 64, 34-41, 2018 | 56 | 2018 |
Primary breast tumor-derived cellular models: characterization of tumorigenic, metastatic, and cancer-associated fibroblasts in dissociated tumor (DT) cultures K Drews-Elger, JA Brinkman, P Miller, SH Shah, JC Harrell, TG Da Silva, ... Breast cancer research and treatment 144, 503-517, 2014 | 43 | 2014 |
A new role for ERα: silencing via DNA methylation of basal, stem cell, and EMT genes EA Ariazi, JC Taylor, MA Black, E Nicolas, MJ Slifker, DJ Azzam, J Boyd Molecular Cancer Research 15 (2), 152-164, 2017 | 37 | 2017 |
DOT1L is a novel cancer stem cell target for triple-negative breast cancer H Kurani, SF Razavipour, KB Harikumar, M Dunworth, AJ Ewald, A Nasir, ... Clinical cancer research 28 (9), 1948-1965, 2022 | 31 | 2022 |
A novel interaction of translocator protein 18 kDa (TSPO) with NADPH oxidase in microglia MK Loth, SR Guariglia, DB Re, J Perez, VN de Paiva, JL Dziedzic, ... Molecular Neurobiology 57, 4467-4487, 2020 | 28 | 2020 |
Potential neuroprotective effects of continuous topiramate therapy in the developing brain MA Mikati, R Daderian, M Zeinieh, AS Leonard, D Azzam, R Kurdi Epilepsy & Behavior 20 (4), 597-601, 2011 | 20 | 2011 |
Programmed cell death in the lithium pilocarpine model: evidence for NMDA receptor and ceramide-mediated mechanisms MA Mikati, E Rizk, S El Dada, M Zeinieh, R Kurdi, J El Hokayem, ... Brain and Development 30 (8), 513-519, 2008 | 13 | 2008 |
Ovarian cancer treatment stratification using ex vivo drug sensitivity testing I Lohse, DJ Azzam, H Al-Ali, CH Volmar, SP Brothers, TA Ince, ... Anticancer research 39 (8), 4023-4030, 2019 | 12 | 2019 |
Surface translocator protein 18 kDa (TSPO) localization on immune cells upon stimulation with LPS and in ART-treated HIV+ subjects LK Blevins, RB Crawford, DJ Azzam, TR Guilarte, NE Kaminski Journal of leukocyte biology 110 (1), 123-140, 2021 | 8 | 2021 |
The Translocator Protein (TSPO) Genetic Polymorphism A147T Is Associated with Worse Survival in Male Glioblastoma Patients KM Troike, AM Acanda de la Rocha, TJ Alban, MM Grabowski, B Otvos, ... Cancers 13 (18), 4525, 2021 | 7 | 2021 |
sVictor, BZ Wiemann, H. Ishwaran, PJ Ter Brugge, J. Jonkers, J. Slingerland MC Boelens, TJ Wu, BY Nabet, B Xu, Y Qiu, T Yoon, DJ Azzam, ... AJ Minn, Cell 159, 499, 2014 | 7 | 2014 |