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Diana Azzam, PhD
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Year
Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways
MC Boelens, TJ Wu, BY Nabet, B Xu, Y Qiu, T Yoon, DJ Azzam, ...
Cell 159 (3), 499-513, 2014
8312014
VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2
D Zhao, C Pan, J Sun, C Gilbert, K Drews-Elger, DJ Azzam, M Picon-Ruiz, ...
Oncogene 34 (24), 3107-3119, 2015
2822015
Interactions between adipocytes and breast cancer cells stimulate cytokine production and drive Src/Sox2/miR-302b–mediated malignant progression
M Picon-Ruiz, C Pan, K Drews-Elger, K Jang, AH Besser, D Zhao, ...
Cancer research 76 (2), 491-504, 2016
1862016
Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer
AE Witt, CW Lee, TI Lee, DJ Azzam, B Wang, C Caslini, F Petrocca, ...
Oncogene 36 (12), 1707-1720, 2017
1622017
Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ‐secretase inhibitor drug responses
DJ Azzam, D Zhao, J Sun, AJ Minn, P Ranganathan, K Drews‐Elger, ...
EMBO molecular medicine 5 (10), 1502-1522, 2013
852013
Dual Src and MEK inhibition decreases ovarian cancer growth and targets tumor initiating stem-like cells
F Simpkins, K Jang, H Yoon, KE Hew, M Kim, DJ Azzam, J Sun, D Zhao, ...
Clinical cancer research 24 (19), 4874-4886, 2018
712018
Combined Src and ER blockade impairs human breast cancer proliferation in vitro and in vivo
Y Chen, EA Alvarez, D Azzam, SA Wander, N Guggisberg, M Jordà, Z Ju, ...
Breast cancer research and treatment 128, 69-78, 2011
682011
Src Inhibition with Saracatinib Reverses Fulvestrant Resistance in ER-Positive Ovarian Cancer Models In Vitro and In Vivo
F Simpkins, P Hevia-Paez, J Sun, W Ullmer, CA Gilbert, T Da Silva, ...
Clinical cancer research 18 (21), 5911-5923, 2012
632012
Imaging neuroinflammation with TSPO: A new perspective on the cellular sources and subcellular localization
TR Guilarte, AN Rodichkin, JL McGlothan, AMA De La Rocha, DJ Azzam
Pharmacology & therapeutics 234, 108048, 2022
592022
Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study
RT Swords, D Azzam, H Al-Ali, I Lohse, CH Volmar, JM Watts, A Perez, ...
Leukemia Research 64, 34-41, 2018
562018
Primary breast tumor-derived cellular models: characterization of tumorigenic, metastatic, and cancer-associated fibroblasts in dissociated tumor (DT) cultures
K Drews-Elger, JA Brinkman, P Miller, SH Shah, JC Harrell, TG Da Silva, ...
Breast cancer research and treatment 144, 503-517, 2014
432014
A new role for ERα: silencing via DNA methylation of basal, stem cell, and EMT genes
EA Ariazi, JC Taylor, MA Black, E Nicolas, MJ Slifker, DJ Azzam, J Boyd
Molecular Cancer Research 15 (2), 152-164, 2017
372017
DOT1L is a novel cancer stem cell target for triple-negative breast cancer
H Kurani, SF Razavipour, KB Harikumar, M Dunworth, AJ Ewald, A Nasir, ...
Clinical cancer research 28 (9), 1948-1965, 2022
312022
A novel interaction of translocator protein 18 kDa (TSPO) with NADPH oxidase in microglia
MK Loth, SR Guariglia, DB Re, J Perez, VN de Paiva, JL Dziedzic, ...
Molecular Neurobiology 57, 4467-4487, 2020
282020
Potential neuroprotective effects of continuous topiramate therapy in the developing brain
MA Mikati, R Daderian, M Zeinieh, AS Leonard, D Azzam, R Kurdi
Epilepsy & Behavior 20 (4), 597-601, 2011
202011
Programmed cell death in the lithium pilocarpine model: evidence for NMDA receptor and ceramide-mediated mechanisms
MA Mikati, E Rizk, S El Dada, M Zeinieh, R Kurdi, J El Hokayem, ...
Brain and Development 30 (8), 513-519, 2008
132008
Ovarian cancer treatment stratification using ex vivo drug sensitivity testing
I Lohse, DJ Azzam, H Al-Ali, CH Volmar, SP Brothers, TA Ince, ...
Anticancer research 39 (8), 4023-4030, 2019
122019
Surface translocator protein 18 kDa (TSPO) localization on immune cells upon stimulation with LPS and in ART-treated HIV+ subjects
LK Blevins, RB Crawford, DJ Azzam, TR Guilarte, NE Kaminski
Journal of leukocyte biology 110 (1), 123-140, 2021
82021
The Translocator Protein (TSPO) Genetic Polymorphism A147T Is Associated with Worse Survival in Male Glioblastoma Patients
KM Troike, AM Acanda de la Rocha, TJ Alban, MM Grabowski, B Otvos, ...
Cancers 13 (18), 4525, 2021
72021
sVictor, BZ Wiemann, H. Ishwaran, PJ Ter Brugge, J. Jonkers, J. Slingerland
MC Boelens, TJ Wu, BY Nabet, B Xu, Y Qiu, T Yoon, DJ Azzam, ...
AJ Minn, Cell 159, 499, 2014
72014
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