Articles with public access mandates - Roebi de BruijnLearn more
Not available anywhere: 2
Exogenous ERα Expression in the Mammary Epithelium Decreases Over Time and Does Not Contribute to p53-Deficient Mammary Tumor Formation in Mice
LM Cornelissen, L Henneman, AP Drenth, E Schut, R de Bruijn, ...
Journal of Mammary Gland Biology and Neoplasia 24, 305-321, 2019
Mandates: Netherlands Organisation for Scientific Research, European Commission
GATA3 truncating mutations promote cistromic re-programming in vitro, but not mammary tumor formation in mice
LM Cornelissen, R de Bruijn, L Henneman, Y Kim, W Zwart, J Jonkers
Journal of Mammary Gland Biology and Neoplasia 24 (3), 271-284, 2019
Mandates: Netherlands Organisation for Scientific Research, European Commission
Available somewhere: 18
Selective loss of PARG restores PARylation and counteracts PARP inhibitor-mediated synthetic lethality
E Gogola, AA Duarte, JR de Ruiter, WW Wiegant, JA Schmid, R de Bruijn, ...
Cancer cell 33 (6), 1078-1093. e12, 2018
Mandates: Swiss National Science Foundation, Danish National Research Foundation …
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
XY Woo, J Giordano, A Srivastava, ZM Zhao, MW Lloyd, R de Bruijn, ...
Nature genetics 53 (1), 86-99, 2021
Mandates: US National Institutes of Health, Health Research Board, Ireland, Science …
Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer
S Annunziato, JR de Ruiter, L Henneman, CS Brambillasca, C Lutz, ...
Nature communications 10 (1), 397, 2019
Mandates: National Health and Medical Research Council, Australia, Netherlands …
Truncated FGFR2 is a clinically actionable oncogene in multiple cancers
D Zingg, J Bhin, J Yemelyanenko, SM Kas, F Rolfs, C Lutz, JK Lee, ...
Nature 608 (7923), 609-617, 2022
Mandates: Swiss National Science Foundation, US National Institutes of Health, German …
MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling
D Zimmerli, CS Brambillasca, F Talens, J Bhin, R Linstra, L Romanens, ...
Nature communications 13 (1), 6579, 2022
Mandates: Swiss National Science Foundation, Netherlands Organisation for Scientific …
TRPS1 acts as a context-dependent regulator of mammary epithelial cell growth/differentiation and breast cancer development
LM Cornelissen, AP Drenth, E Van Der Burg, R De Bruijn, CEJ Pritchard, ...
Genes & development 34 (3-4), 179-193, 2020
Mandates: Netherlands Organisation for Scientific Research, European Commission, Dutch …
CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer
JM Houthuijzen, R De Bruijn, E Van Der Burg, AP Drenth, E Wientjens, ...
Nature Communications 14 (1), 183, 2023
Mandates: Netherlands Organisation for Scientific Research, Cancer Research UK, Dutch …
Functional Categorization of BRCA1 Variants of Uncertain Clinical Significance in Homologous Recombination Repair Complementation Assays
P Bouwman, I van der Heijden, H van der Gulden, R de Bruijn, ...
Clinical Cancer Research 26 (17), 4559-4568, 2020
Mandates: Netherlands Organisation for Scientific Research, Dutch Cancer Society
Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1-versus BRCA2-deficient mammary tumors
J Bhin, MP Dias, E Gogola, F Rolfs, SR Piersma, R de Bruijn, JR de Ruiter, ...
Cell reports 42 (5), 2023
Mandates: Swiss National Science Foundation, Netherlands Organisation for Scientific …
Homologous recombination deficiency derived from whole-genome sequencing predicts platinum response in triple-negative breast cancers
P Ter Brugge, SC Moser, I Bièche, P Kristel, S Ibadioune, A Eeckhoutte, ...
Nature Communications 14 (1), 1958, 2023
Mandates: Dutch Cancer Society
Response of metastatic mouse invasive lobular carcinoma to mTOR inhibition is partly mediated by the adaptive immune system
S Klarenbeek, CW Doornebal, SM Kas, N Bonzanni, J Bhin, ...
Oncoimmunology 9 (1), 1724049, 2020
Mandates: Netherlands Organisation for Scientific Research, European Commission, Dutch …
Epithelial-to-mesenchymal transition drives invasiveness of breast cancer brain metastases
AS Margarido, R Uceda-Castro, K Hahn, R de Bruijn, L Kester, I Hofland, ...
Cancers 14 (13), 3115, 2022
Mandates: Swiss National Science Foundation, Fundação para a Ciência e a Tecnologia …
Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer
L Ratz, C Brambillasca, L Bartke, MA Huetzen, J Goergens, O Leidecker, ...
Breast Cancer Research 24 (1), 41, 2022
Mandates: German Research Foundation, Netherlands Organisation for Scientific Research …
A BRCA1 coiled-coil domain variant disrupting PALB2 interaction promotes the development of mammary tumors and confers a targetable defect in homologous recombination repair
EM Pulver, C Mukherjee, G van de Kamp, SJ Roobol, MB Rother, ...
Cancer research 81 (24), 6171-6182, 2021
Mandates: Swiss National Science Foundation, US National Institutes of Health …
A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression
SJ Hutten, R de Bruijn, C Lutz, M Badoux, T Eijkman, X Chao, M Ciwinska, ...
Cancer cell 41 (5), 986-1002. e9, 2023
Mandates: US National Institutes of Health, Cancer Research UK, UK Medical Research …
MYC promotes immune-suppression in TNBC via inhibition of IFN signaling
D Zimmerli, CS Brambillasca, F Talens, J Bhin, A Bhattacharya, ...
bioRxiv, 2021.02. 24.432659, 2021
Mandates: Swiss National Science Foundation, Netherlands Organisation for Scientific …
H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours
D Dibitetto, M Liptay, F Vivalda, H Dogan, E Gogola, ...
Nature communications 15 (1), 4430, 2024
Mandates: European Commission
EZH2 Inhibition Sensitizes BRCA1-Deficient Breast Cancer to Synthetic Lethal Therapy with ATM Inhibitors
L Ratz, C Brambillasca, L Bartke, M van de Ven, N Proost, B Siteur, ...
Mandates: German Research Foundation, Netherlands Organisation for Scientific Research …
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