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Biomaterials: foreign bodies or tuners for the immune response? E Mariani, G Lisignoli, RM Borzì, L Pulsatelli International journal of molecular sciences 20 (3), 636, 2019 | 610 | 2019 |
Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis MB Goldring, M Otero, DA Plumb, C Dragomir, M Favero, K El Hachem, ... European cells & materials 21, 202, 2011 | 579 | 2011 |
Enhanced and coordinated in vivo expression of inflammatory cytokines and nitric oxide synthase by chondrocytes from patients with osteoarthritis C Melchiorri, R Meliconi, L Frizziero, T Silvestri, L Pulsatelli, I Mazzetti, ... Arthritis & Rheumatism 41 (12), 2165-2174, 1998 | 336 | 1998 |
p16INK4a and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodeling in osteoarthritis D Philipot, D Guérit, D Platano, P Chuchana, E Olivotto, F Espinoza, ... Arthritis research & therapy 16, 1-12, 2014 | 251 | 2014 |
Human chondrocytes express functional chemokine receptors and release matrix‐degrading enzymes in response to C‐X‐C and C‐C chemokines RM Borzì, I Mazzetti, L Cattini, M Uguccioni, M Baggiolini, A Facchini Arthritis & Rheumatism: Official Journal of the American College of …, 2000 | 196 | 2000 |
Flow cytometric analysis of intracellular chemokines in chondrocytes in vivo: constitutive expression and enhancement in osteoarthritis and rheumatoid arthritis RM Borzı̀, I Mazzetti, S Macor, T Silvestri, A Bassi, L Cattini, A Facchini FEBS letters 455 (3), 238-242, 1999 | 130 | 1999 |
mTOR, AMPK, and Sirt1: key players in metabolic stress management S Cetrullo, S D'Adamo, B Tantini, RM Borzi, F Flamigni Critical Reviews™ in Eukaryotic Gene Expression 25 (1), 2015 | 112 | 2015 |
Serum copper/zinc superoxide dismutase levels in patients with rheumatoid arthritis I Mazzetti, B Grigolo, RM Borzi, R Meliconi, A Facchini International Journal of Clinical and Laboratory Research 26, 245-249, 1996 | 101 | 1996 |
Chemokines in cartilage degradation. RM Borzì, I Mazzetti, KB Marcu, A Facchini Clinical Orthopaedics and Related Research (1976-2007) 427, S53-S61, 2004 | 96 | 2004 |
Emerging players at the intersection of chondrocyte loss of maturational arrest, oxidative stress, senescence and low‐grade inflammation in osteoarthritis M Minguzzi, S Cetrullo, S D’Adamo, Y Silvestri, F Flamigni, RM Borzì Oxidative medicine and cellular longevity 2018 (1), 3075293, 2018 | 91 | 2018 |
Differential requirements for IKKα and IKKβ in the differentiation of primary human osteoarthritic chondrocytes E Olivotto, RM Borzi, R Vitellozzi, S Pagani, A Facchini, M Battistelli, ... Arthritis & Rheumatism 58 (1), 227-239, 2008 | 90 | 2008 |
Molecular mechanisms contributing to mesenchymal stromal cell aging S Neri, RM Borzì Biomolecules 10 (2), 340, 2020 | 87 | 2020 |
Hydroxytyrosol prevents chondrocyte death under oxidative stress by inducing autophagy through sirtuin 1-dependent and-independent mechanisms S Cetrullo, S D'Adamo, S Guidotti, RM Borzì, F Flamigni Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (6), 1181-1191, 2016 | 83 | 2016 |
A role for chemokines in the induction of chondrocyte phenotype modulation I Mazzetti, G Magagnoli, S Paoletti, M Uguccioni, E Olivotto, R Vitellozzi, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2004 | 81 | 2004 |
Human osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1β-stimulated production of chemokines … E Assirelli, L Pulsatelli, P Dolzani, D Platano, E Olivotto, G Filardo, ... PloS one 9 (5), e96925, 2014 | 74 | 2014 |
Matrix metalloproteinase 13 loss associated with impaired extracellular matrix remodeling disrupts chondrocyte differentiation by concerted effects on multiple regulatory factors RM Borzí, E Olivotto, S Pagani, R Vitellozzi, S Neri, M Battistelli, E Falcieri, ... Arthritis & Rheumatism 62 (8), 2370-2381, 2010 | 61 | 2010 |
Hydroxytyrosol modulates the levels of microRNA-9 and its target sirtuin-1 thereby counteracting oxidative stress-induced chondrocyte death S D'Adamo, S Cetrullo, S Guidotti, RM Borzi, F Flamigni Osteoarthritis and Cartilage 25 (4), 600-610, 2017 | 59 | 2017 |
Spermidine rescues the deregulated autophagic response to oxidative stress of osteoarthritic chondrocytes S D'Adamo, S Cetrullo, S Guidotti, Y Silvestri, M Minguzzi, S Santi, ... Free Radical Biology and Medicine 153, 159-172, 2020 | 54 | 2020 |
Sulforaphane protects human chondrocytes against cell death induced by various stimuli A Facchini, I Stanic, S Cetrullo, RM Borzì, G Filardo, F Flamigni Journal of cellular physiology 226 (7), 1771-1779, 2011 | 54 | 2011 |