Articles with public access mandates - Dominic HoepfnerLearn more
Available somewhere: 24
Selective and specific inhibition of the Plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin
D Hoepfner, CW McNamara, CS Lim, C Studer, R Riedl, T Aust, ...
Cell host & microbe 11 (6), 654-663, 2012
Mandates: US National Institutes of Health
Evidence for a functionally relevant rocaglamide binding site on the eIF4A–RNA complex
H Sadlish, G Galicia-Vazquez, CG Paris, T Aust, B Bhullar, L Chang, ...
ACS chemical biology 8 (7), 1519-1527, 2013
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
Biosynthesis of fragin is controlled by a novel quorum sensing signal
C Jenul, S Sieber, C Daeppen, A Mathew, M Lardi, G Pessi, D Hoepfner, ...
Nature communications 9 (1), 1297, 2018
Mandates: Swiss National Science Foundation
Molecular basis for the functional interaction of dynein light chain with the nuclear-pore complex
P Stelter, R Kunze, D Flemming, D Höpfner, M Diepholz, P Philippsen, ...
Nature Cell Biology 9 (7), 788-796, 2007
Mandates: German Research Foundation
TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks
K Shimada, I Filipuzzi, M Stahl, SB Helliwell, C Studer, D Hoepfner, ...
Molecular cell 51 (6), 829-839, 2013
Mandates: Swiss National Science Foundation
The marine natural product manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells
G Kallifatidis, D Hoepfner, T Jaeg, EA Guzmán, AE Wright
Marine drugs 11 (9), 3500-3516, 2013
Mandates: US National Institutes of Health
Decatransin, a new natural product inhibiting protein translocation at the Sec61/SecYEG translocon
T Junne, J Wong, C Studer, T Aust, BW Bauer, M Beibel, B Bhullar, ...
Journal of cell science 128 (6), 1217-1229, 2015
Mandates: Swiss National Science Foundation, US National Institutes of Health, Howard …
A reversible haploid mouse embryonic stem cell biobank resource for functional genomics
U Elling, RA Wimmer, A Leibbrandt, T Burkard, G Michlits, A Leopoldi, ...
Nature 550 (7674), 114-118, 2017
Mandates: US Department of Defense, Austrian Science Fund, European Commission
Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease
S Khare, SL Roach, SW Barnes, D Hoepfner, JR Walker, AK Chatterjee, ...
PLoS Pathogens 11 (7), e1005058, 2015
Mandates: US National Institutes of Health
Discovery of a ZIP7 inhibitor from a Notch pathway screen
E Nolin, S Gans, L Llamas, S Bandyopadhyay, SM Brittain, ...
Nature chemical biology 15 (2), 179-188, 2019
Mandates: US National Institutes of Health
The novolactone natural product disrupts the allosteric regulation of Hsp70
AQ Hassan, CA Kirby, W Zhou, T Schuhmann, R Kityk, DR Kipp, J Baird, ...
Chemistry & biology 22 (1), 87-97, 2015
Mandates: US Department of Energy, German Research Foundation
Jawsamycin exhibits in vivo antifungal properties by inhibiting Spt14/Gpi3-mediated biosynthesis of glycosylphosphatidylinositol
Y Fu, D Estoppey, S Roggo, D Pistorius, F Fuchs, C Studer, AS Ibrahim, ...
Nature communications 11 (1), 3387, 2020
Mandates: US National Institutes of Health
Target identification and mechanism of action of picolinamide and benzamide chemotypes with antifungal properties
V Pries, C Nöcker, D Khan, P Johnen, Z Hong, A Tripathi, AL Keller, M Fitz, ...
Cell chemical biology 25 (3), 279-290. e7, 2018
Mandates: US National Institutes of Health, German Research Foundation, European …
Stendomycin selectively inhibits TIM23-dependent mitochondrial protein import
I Filipuzzi, J Steffen, M Germain, L Goepfert, MA Conti, C Potting, R Cerino, ...
Nature chemical biology 13 (12), 1239-1244, 2017
Mandates: US National Institutes of Health, German Research Foundation
A common mechanism of Sec61 translocon inhibition by small molecules
S Itskanov, L Wang, T Junne, R Sherriff, L Xiao, N Blanchard, WQ Shi, ...
Nature chemical biology 19 (9), 1063-1071, 2023
Mandates: Swiss National Science Foundation, US National Institutes of Health
Auxin-inducible depletion of the essentialome suggests inhibition of TORC1 by auxins and inhibition of vrg4 by SDZ 90-215, a natural antifungal cyclopeptide
NA Snyder, A Kim, L Kester, AN Gale, C Studer, D Hoepfner, S Roggo, ...
G3: Genes, Genomes, Genetics 9 (3), 829-840, 2019
Mandates: US National Institutes of Health
Robust and versatile arrayed libraries for human genome-wide CRISPR activation, deletion and silencing
JA Yin, L Frick, MC Scheidmann, T Liu, C Trevisan, A Dhingra, A Spinelli, ...
BioRxiv, 2022.05. 25.493370, 2022
Mandates: Swiss National Science Foundation, European Commission
MHO1, an Evolutionarily Conserved Gene, Is Synthetic Lethal with PLC1; Mho1p Has a Role in Invasive Growth
ID Schlatter, M Meira, V Ueberschlag, D Hoepfner, R Movva, NE Hynes
PloS one 7 (3), e32501, 2012
Mandates: Swiss National Science Foundation
Direct interaction of Chivosazole F with actin elicits cell responses similar to Latrunculin A but distinct from Chondramide
I Filipuzzi, JR Thomas, V Pries, D Estoppey, M Salcius, C Studer, ...
ACS chemical biology 12 (9), 2264-2269, 2017
Mandates: US National Institutes of Health
PrP-containing aggresomes are cytosolic components of an ER quality control mechanism
T Dubnikov, T Ben-Gedalya, R Reiner, D Hoepfner, WA Cabral, JC Marini, ...
Journal of cell science 129 (19), 3635-3647, 2016
Mandates: European Commission
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