Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer S Misale, R Yaeger, S Hobor, E Scala, M Janakiraman, D Liska, E Valtorta, ... Nature 486 (7404), 532-536, 2012 | 2059 | 2012 |
Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients G Siravegna, B Mussolin, M Buscarino, G Corti, A Cassingena, ... Nature medicine 21 (7), 795-801, 2015 | 1123 | 2015 |
A molecularly annotated platform of patient-derived xenografts (“xenopatients”) identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer A Bertotti, G Migliardi, F Galimi, F Sassi, D Torti, C Isella, D Corà, ... Cancer discovery 1 (6), 508-523, 2011 | 1022 | 2011 |
Interrogating open issues in cancer precision medicine with patient-derived xenografts AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ... Nature Reviews Cancer 17 (4), 254-268, 2017 | 677 | 2017 |
Stromal contribution to the colorectal cancer transcriptome C Isella, A Terrasi, SE Bellomo, C Petti, G Galatola, A Muratore, A Mellano, ... Nature genetics 47 (4), 312-319, 2015 | 656 | 2015 |
FLAME, a novel fuzzy clustering method for the analysis of DNA microarray data L Fu, E Medico BMC bioinformatics 8, 1-15, 2007 | 646 | 2007 |
Expression of the Met/HGF receptor in normal and neoplastic human tissues. MF Di Renzo, RP Narsimhan, M Olivero, S Bretti, S Giordano, E Medico, ... Oncogene 6 (11), 1997-2003, 1991 | 643 | 1991 |
Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer F De Bacco, P Luraghi, E Medico, G Reato, F Girolami, T Perera, ... JNCI: Journal of the National Cancer Institute 103 (8), 645-661, 2011 | 379 | 2011 |
The MET oncogene drives a genetic programme linking cancer to haemostasis C Boccaccio, G Sabatino, E Medico, F Girolami, A Follenzi, G Reato, ... Nature 434 (7031), 396-400, 2005 | 326 | 2005 |
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets E Medico, M Russo, G Picco, C Cancelliere, E Valtorta, G Corti, ... Nature communications 6 (1), 7002, 2015 | 307 | 2015 |
Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer C Isella, F Brundu, SE Bellomo, F Galimi, E Zanella, R Porporato, C Petti, ... Nature communications 8 (1), 15107, 2017 | 279 | 2017 |
Neural differentiation of human mesenchymal stem cells: Evidence for expression of neural markers and eag K+ channel types K Mareschi, M Novara, D Rustichelli, I Ferrero, D Guido, E Carbone, ... Experimental hematology 34 (11), 1563-1572, 2006 | 239 | 2006 |
Increased lactate secretion by cancer cells sustains non-cell-autonomous adaptive resistance to MET and EGFR targeted therapies M Apicella, E Giannoni, S Fiore, KJ Ferrari, D Fernández-Pérez, C Isella, ... Cell metabolism 28 (6), 848-865. e6, 2018 | 225 | 2018 |
Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells M De Palma, E Montini, FRS de Sio, F Benedicenti, A Gentile, E Medico, ... Blood 105 (6), 2307-2315, 2005 | 211 | 2005 |
Phosphorylation of serine 985 negatively regulates the hepatocyte growth factor receptor kinase. L Gandino, P Longati, E Medico, M Prat, PM Comoglio Journal of Biological Chemistry 269 (3), 1815-1820, 1994 | 202 | 1994 |
Transfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogene. S Giordano, Z Zhen, E Medico, G Gaudino, F Galimi, PM Comoglio Proceedings of the National Academy of Sciences 90 (2), 649-653, 1993 | 188 | 1993 |
Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasms R Piva, L Agnelli, E Pellegrino, K Todoerti, V Grosso, I Tamagno, ... Journal of clinical oncology 28 (9), 1583-1590, 2010 | 179 | 2010 |
The tyrosine kinase receptors Ron and Sea control" scattering" and morphogenesis of liver progenitor cells in vitro. E Medico, AM Mongiovi, J Huff, MA Jelinek, A Follenzi, G Gaudino, ... Molecular biology of the cell 7 (4), 495-504, 1996 | 172 | 1996 |
The MET Oncogene Is a Functional Marker of a Glioblastoma Stem Cell Subtype F De Bacco, E Casanova, E Medico, S Pellegatta, F Orzan, R Albano, ... Cancer research 72 (17), 4537-4550, 2012 | 164 | 2012 |
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts XY Woo, J Giordano, A Srivastava, ZM Zhao, MW Lloyd, R de Bruijn, ... Nature genetics 53 (1), 86-99, 2021 | 155 | 2021 |