Lung adenocarcinoma promotion by air pollutants W Hill, EL Lim, CE Weeden, C Lee, M Augustine, K Chen, FC Kuan, ... Nature 616 (7955), 159-167, 2023 | 288 | 2023 |
Targeting aberrant epigenetic networks mediated by PRMT1 and KDM4C in acute myeloid leukemia N Cheung, TK Fung, BB Zeisig, K Holmes, JK Rane, KA Mowen, MG Finn, ... Cancer cell 29 (1), 32-48, 2016 | 175 | 2016 |
Synthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors MT Esposito, L Zhao, TK Fung, JK Rane, A Wilson, N Martin, J Gil, ... Nature medicine 21 (12), 1481-1490, 2015 | 172 | 2015 |
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA C Abbosh, AM Frankell, T Harrison, J Kisistok, A Garnett, L Johnson, ... Nature 616 (7957), 553-562, 2023 | 125 | 2023 |
The evolution of lung cancer and impact of subclonal selection in TRACERx AM Frankell, M Dietzen, M Al Bakir, EL Lim, T Karasaki, S Ward, ... Nature 616 (7957), 525-533, 2023 | 123 | 2023 |
miR-25 Modulates Invasiveness and Dissemination of Human Prostate Cancer Cells via Regulation of αv- and α6-Integrin Expression E Zoni, G van der Horst, AF van de Merbel, L Chen, JK Rane, RCM Pelger, ... Cancer research 75 (11), 2326-2336, 2015 | 102 | 2015 |
Antibodies against endogenous retroviruses promote lung cancer immunotherapy KW Ng, J Boumelha, KSS Enfield, J Almagro, H Cha, O Pich, T Karasaki, ... Nature 616 (7957), 563-573, 2023 | 101 | 2023 |
Evolutionary analysis indicates that DNA alkylation damage is a byproduct of cytosine DNA methyltransferase activity S Rošić, R Amouroux, CE Requena, A Gomes, M Emperle, T Beltran, ... Nature genetics 50 (3), 452-459, 2018 | 85 | 2018 |
MicroRNA expression profile of primary prostate cancer stem cells as a source of biomarkers and therapeutic targets JK Rane, M Scaravilli, A Ylipää, D Pellacani, VM Mann, MS Simms, ... European urology 67 (1), 7-10, 2015 | 81 | 2015 |
The evolution of non-small cell lung cancer metastases in TRACERx M Al Bakir, A Huebner, C Martínez-Ruiz, K Grigoriadis, TBK Watkins, ... Nature 616 (7957), 534-542, 2023 | 80 | 2023 |
Genomic–transcriptomic evolution in lung cancer and metastasis C Martínez-Ruiz, JRM Black, C Puttick, MS Hill, J Demeulemeester, ... Nature 616 (7957), 543-552, 2023 | 73 | 2023 |
Advanced prostate cancer—a case for adjuvant differentiation therapy JK Rane, D Pellacani, NJ Maitland Nature reviews Urology 9 (10), 595-602, 2012 | 53 | 2012 |
Inhibition of the glucocorticoid receptor results in an enhanced miR-99a/100-mediated radiation response in stem-like cells from human prostate cancers JK Rane, HHH Erb, G Nappo, VM Mann, MS Simms, AT Collins, ... Oncotarget 7 (32), 51965, 2016 | 44 | 2016 |
Evolutionary characterization of lung adenocarcinoma morphology in TRACERx T Karasaki, DA Moore, S Veeriah, C Naceur-Lombardelli, A Toncheva, ... Nature medicine 29 (4), 833-845, 2023 | 41 | 2023 |
Body composition and lung cancer-associated cachexia in TRACERx O Al-Sawaf, J Weiss, M Skrzypski, JM Lam, T Karasaki, F Zambrana, ... Nature medicine 29 (4), 846-858, 2023 | 34 | 2023 |
Mechanistic rationale for MCL1 inhibition during androgen deprivation therapy FR Santer, HHH Erb, SJ Oh, F Handle, GE Feiersinger, B Luef, H Bu, ... Oncotarget 6 (8), 6105, 2015 | 34 | 2015 |
CIP2A is a candidate therapeutic target in clinically challenging prostate cancer cell populations A Khanna, JK Rane, KK Kivinummi, A Urbanucci, MA Helenius, ... Oncotarget 6 (23), 19661, 2015 | 32 | 2015 |
Telomerase activity and telomere length in human benign prostatic hyperplasia stem-like cells and their progeny implies the existence of distinct basal and luminal cell lineages JK Rane, S Greener, FM Frame, VM Mann, MS Simms, AT Collins, ... European urology 69 (4), 551-554, 2016 | 25 | 2016 |
Conserved two-step regulatory mechanism of human epithelial differentiation JK Rane, AP Droop, D Pellacani, ES Polson, MS Simms, AT Collins, ... Stem cell reports 2 (2), 180-188, 2014 | 21 | 2014 |
Efficacy and cardiotoxic safety profile of raltitrexed in fluoropyrimidines-pretreated or high-risk cardiac patients with GI malignancies: large single-center experience K Khan, JK Rane, D Cunningham, S Rao, D Watkins, N Starling, ... Clinical Colorectal Cancer 18 (1), 64-71. e1, 2019 | 16 | 2019 |