| Nitric oxide scavenging by red blood cell microparticles and cell-free hemoglobin as a mechanism for the red cell storage lesion C Donadee, NJH Raat, T Kanias, J Tejero, JS Lee, EE Kelley, X Zhao, ... Circulation 124 (4), 465-476, 2011 | 659 | 2011 |
| An aged immune system drives senescence and ageing of solid organs MJ Yousefzadeh, RR Flores, YI Zhu, ZC Schmiechen, RW Brooks, ... Nature 594 (7861), 100-105, 2021 | 535 | 2021 |
| Hydrogen peroxide is the major oxidant product of xanthine oxidase EE Kelley, NKH Khoo, NJ Hundley, UZ Malik, BA Freeman, MM Tarpey Free Radical Biology and Medicine 48 (4), 493-498, 2010 | 452 | 2010 |
| Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent AL King, DJ Polhemus, S Bhushan, H Otsuka, K Kondo, CK Nicholson, ... Proceedings of the National Academy of Sciences 111 (8), 3182-3187, 2014 | 398 | 2014 |
| Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling I Al Ghouleh, NKH Khoo, UG Knaus, KK Griendling, RM Touyz, ... Free Radical Biology and Medicine 51 (7), 1271-1288, 2011 | 286 | 2011 |
| Inhaled NO accelerates restoration of liver function in adults following orthotopic liver transplantation JD Lang, X Teng, P Chumley, JH Crawford, TS Isbell, BK Chacko, Y Liu, ... The Journal of clinical investigation 117 (9), 2583-2591, 2007 | 269 | 2007 |
| Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species ER Hahm, MB Moura, EE Kelley, B Van Houten, S Shiva, SV Singh PloS one 6 (8), e23354, 2011 | 251 | 2011 |
| Xanthine oxidoreductase-catalyzed reactive species generation: a process in critical need of reevaluation N Cantu-Medellin, EE Kelley Redox biology 1 (1), 353-358, 2013 | 247 | 2013 |
| Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells D Xiao, AA Powolny, MB Moura, EE Kelley, A Bommareddy, SH Kim, ... Journal of Biological Chemistry 285 (34), 26558-26569, 2010 | 194 | 2010 |
| Uric acid and hypertension: an update with recommendations LG Sanchez-Lozada, B Rodriguez-Iturbe, EE Kelley, T Nakagawa, ... American journal of hypertension 33 (7), 583-594, 2020 | 173 | 2020 |
| Xanthine oxidoreductase-catalyzed reduction of nitrite to nitric oxide: insights regarding where, when and how N Cantu-Medellin, EE Kelley Nitric Oxide 34, 19-26, 2013 | 167 | 2013 |
| Comparing β-carotene, vitamin E and nitric oxide as membrane antioxidants FQ Schafer, HP Wang, EE Kelley, KL Cueno, SMMGR Buettner Walter de Gruyter 383 (3-4), 671-681, 2002 | 159 | 2002 |
| Nox2 B-loop peptide, Nox2ds, specifically inhibits the NADPH oxidase Nox2 G Csányi, E Cifuentes-Pagano, I Al Ghouleh, DJ Ranayhossaini, L Egaña, ... Free Radical Biology and Medicine 51 (6), 1116-1125, 2011 | 143 | 2011 |
| Febuxostat inhibition of endothelial-bound XO: implications for targeting vascular ROS production UZ Malik, NJ Hundley, G Romero, R Radi, BA Freeman, MM Tarpey, ... Free Radical Biology and Medicine 51 (1), 179-184, 2011 | 140 | 2011 |
| Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging AR Robinson, MJ Yousefzadeh, TA Rozgaja, J Wang, X Li, JS Tilstra, ... Redox biology 17, 259-273, 2018 | 120 | 2018 |
| Thrombospondin-1 regulates blood flow via CD47 receptor–mediated activation of NADPH oxidase 1 G Csányi, M Yao, AI Rodríguez, IA Ghouleh, M Sharifi-Sanjani, ... Arteriosclerosis, thrombosis, and vascular biology 32 (12), 2966-2973, 2012 | 119 | 2012 |
| The impact of xanthine oxidase (XO) on hemolytic diseases HM Schmidt, EE Kelley, AC Straub Redox Biology 21, 101072, 2019 | 113 | 2019 |
| Activation of the aryl hydrocarbon receptor sensitizes mice to nonalcoholic steatohepatitis by deactivating mitochondrial sirtuin deacetylase Sirt3 J He, B Hu, X Shi, ER Weidert, P Lu, M Xu, M Huang, EE Kelley, W Xie Molecular and cellular biology 33 (10), 2047-2055, 2013 | 113 | 2013 |
| Nitrite-generated NO circumvents dysregulated arginine/NOS signaling to protect against intimal hyperplasia in Sprague-Dawley rats MJ Alef, R Vallabhaneni, E Carchman, SM Morris, S Shiva, Y Wang, ... The Journal of clinical investigation 121 (4), 1646-1656, 2011 | 113 | 2011 |
| Xanthine oxidase–dependent regulation of hypoxia-inducible factor in cancer cells CE Griguer, CR Oliva, EE Kelley, GI Giles, JR Lancaster Jr, GY Gillespie Cancer research 66 (4), 2257-2263, 2006 | 113 | 2006 |
Bruce FreemanIrwin Fridovich Distinguished Professor and Chair Dept Pharmacology & Chemical Biology, University of Pittsburgh School of MedicineVerified email at complexarx.com
