The translational landscape of mTOR signalling steers cancer initiation and metastasis AC Hsieh, Y Liu, MP Edlind, NT Ingolia, MR Janes, A Sher, EY Shi, ... Nature 485 (7396), 55-61, 2012 | 1470 | 2012 |
Assessment of the sensitivity and specificity of oligonucleotide (50mer) microarrays MD Kane, TA Jatkoe, CR Stumpf, J Lu, JD Thomas, SJ Madore Nucleic acids research 28 (22), 4552-4557, 2000 | 863 | 2000 |
Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning N Kondrashov, A Pusic, CR Stumpf, K Shimizu, AC Hsieh, S Xue, ... Cell 145 (3), 383-397, 2011 | 630 | 2011 |
Translation control of the immune checkpoint in cancer and its therapeutic targeting Y Xu, M Poggio, HY Jin, Z Shi, CM Forester, Y Wang, CR Stumpf, L Xue, ... Nature medicine 25 (2), 301-311, 2019 | 228 | 2019 |
The translational landscape of the mammalian cell cycle CR Stumpf, MV Moreno, AB Olshen, BS Taylor, D Ruggero Molecular cell 52 (4), 574-582, 2013 | 226 | 2013 |
Analyzing mRNA–protein complexes using a yeast three-hybrid system DS Bernstein, N Buter, C Stumpf, M Wickens Methods 26 (2), 123-141, 2002 | 175 | 2002 |
Structure-based design of pyridone–aminal eFT508 targeting dysregulated translation by selective mitogen-activated protein kinase interacting kinases 1 and 2 (MNK1/2) inhibition SH Reich, PA Sprengeler, GG Chiang, JR Appleman, J Chen, J Clarine, ... Journal of medicinal chemistry 61 (8), 3516-3540, 2018 | 149 | 2018 |
The cancerous translation apparatus CR Stumpf, D Ruggero Current opinion in genetics & development 21 (4), 474-483, 2011 | 130 | 2011 |
A 5′ cytosine binding pocket in Puf3p specifies regulation of mitochondrial mRNAs D Zhu, CR Stumpf, JM Krahn, M Wickens, TMT Hall Proceedings of the National Academy of Sciences 106 (48), 20192-20197, 2009 | 106 | 2009 |
Assessing gene-level translational control from ribosome profiling AB Olshen, AC Hsieh, CR Stumpf, RA Olshen, D Ruggero, BS Taylor Bioinformatics 29 (23), 2995-3002, 2013 | 105 | 2013 |
A Caenorhabditis elegans PUF protein family with distinct RNA binding specificity CR Stumpf, J Kimble, M Wickens Rna 14 (8), 1550-1557, 2008 | 63 | 2008 |
A single C. elegans PUF protein binds RNA in multiple modes YY Koh, L Opperman, C Stumpf, A Mandan, S Keles, M Wickens Rna 15 (6), 1090-1099, 2009 | 58 | 2009 |
Context-dependent function of a conserved translational regulatory module Q Liu, C Stumpf, C Thomas, M Wickens, ES Haag Development 139 (8), 1509-1521, 2012 | 33 | 2012 |
Analysis of RNA–protein interactions using a yeast three-hybrid system CR Stumpf, L Opperman, M Wickens Methods in enzymology 449, 295-315, 2008 | 32 | 2008 |
Zotatifin, an eIF4A-selective inhibitor, blocks tumor growth in receptor tyrosine kinase driven tumors A Gerson-Gurwitz, NP Young, VK Goel, B Eam, CR Stumpf, J Chen, ... Frontiers in Oncology 11, 766298, 2021 | 25 | 2021 |
A highly selective MNK inhibitor rescues deficits associated with fragile X syndrome in mice T Shukla, JB de la Peña, JM Perish, JE Ploski, CR Stumpf, KR Webster, ... Neurotherapeutics 18 (1), 624-639, 2021 | 12 | 2021 |
Investigating Myc-dependent translational regulation in normal and cancer cells JT Cunningham, M Pourdehnad, CR Stumpf, D Ruggero The Myc Gene: Methods and Protocols, 201-212, 2013 | 10 | 2013 |
Inhibition of MNK by eFT508 reprograms T-cell signaling to promote an antitumor immune response CR Stumpf, J Chen, VK Goel, GS Parker, GG Chiang, PA Thompson, ... Cancer Research 78 (13_Supplement), 3855-3855, 2018 | 6 | 2018 |
eFT226, a first in class inhibitor of eIF4A1, targets FEGFR1/2 and HER2 driven cancers PA Thompson, NP Young, CR Stumpf, B Eam, VK Goel, J Chen, S Fish, ... Molecular Cancer Therapeutics 18 (12), 2019 | 4 | 2019 |
A focused CRISPR screen to identify synthetic lethal interactions with the novel eIF4A inhibitor eFT226 in KRAS driven NSCLC NP Young, RS Craig, J Chen, GG Chiang, PA Thompson, KR Webster American Association for Cancer Research (AACR) Annual Meeting, Atlanta, GA, 2019 | 4 | 2019 |