Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets LV Wain, N Shrine, MS Artigas, AM Erzurumluoglu, B Noyvert, ... Nature genetics 49 (3), 416-425, 2017 | 303 | 2017 |
Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis MD Mayes, L Bossini-Castillo, O Gorlova, JE Martin, X Zhou, WV Chen, ... The American Journal of Human Genetics 94 (1), 47-61, 2014 | 256 | 2014 |
Gene expression variability across cells and species shapes innate immunity T Hagai, X Chen, RJ Miragaia, R Rostom, T Gomes, N Kunowska, ... Nature 563 (7730), 197-202, 2018 | 210 | 2018 |
A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility. FD Carmona, SL Mackie, JE Martín, JC Taylor, A Vaglio, S Eyre, ... American Journal of Human Genetics 96 (4), 565-80, 2015 | 192 | 2015 |
GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways E López-Isac, M Acosta-Herrera, M Kerick, S Assassi, AT Satpathy, ... Nature communications 10 (1), 4955, 2019 | 143 | 2019 |
HLA-DRA variants predict penicillin allergy in genome-wide fine-mapping genotyping JL Guéant, A Romano, JA Cornejo-Garcia, A Oussalah, C Chery, ... Journal of Allergy and Clinical Immunology 135 (1), 253-259. e10, 2015 | 100 | 2015 |
A rare polymorphism in the gene for Toll‐like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediators JCA Broen, L Bossini‐Castillo, L Van Bon, MC Vonk, H Knaapen, ... Arthritis & Rheumatism 64 (1), 264-271, 2012 | 100 | 2012 |
Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases B Soskic, E Cano-Gamez, DJ Smyth, WC Rowan, N Nakic, ... Nature genetics 51 (10), 1486-1493, 2019 | 99 | 2019 |
A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations L Bossini-Castillo, JE Martin, J Broen, O Gorlova, CP Simeón, L Beretta, ... Human molecular genetics 21 (4), 926-933, 2012 | 95 | 2012 |
IRF5 polymorphism predicts prognosis in patients with systemic sclerosis R Sharif, MD Mayes, FK Tan, OY Gorlova, LK Hummers, AA Shah, ... Annals of the rheumatic diseases 71 (7), 1197-1202, 2012 | 91 | 2012 |
Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk JG Pouget, ... Human Molecular Genetics 28 (20), 3498-3513, 2019 | 86 | 2019 |
A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides L Bossini-Castillo, C De Kovel, H Kallberg, R van‘t Slot, A Italiaander, ... Annals of the rheumatic diseases 74 (3), e15-e15, 2015 | 86 | 2015 |
Immunogenetics of systemic sclerosis: defining heritability, functional variants and shared-autoimmunity pathways L Bossini-Castillo, E López-Isac, J Martín Journal of autoimmunity 64, 53-65, 2015 | 82 | 2015 |
A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort L Bossini-Castillo, JCA Broen, CP Simeon, L Beretta, MC Vonk, ... Annals of the rheumatic diseases 70 (4), 638-641, 2011 | 81 | 2011 |
Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation B Soskic, E Cano-Gamez, DJ Smyth, K Ambridge, Z Ke, JC Matte, ... Nature genetics 54 (6), 817-826, 2022 | 75 | 2022 |
Confirmation of TNIP1 but not RHOB and PSORS1C1 as systemic sclerosis risk factors in a large independent replication study L Bossini-Castillo, JE Martin, J Broen, CP Simeon, L Beretta, OY Gorlova, ... Annals of the rheumatic diseases 72 (4), 602-607, 2013 | 72 | 2013 |
Association of MicroRNA‐618 expression with altered frequency and activation of plasmacytoid dendritic cells in patients with systemic sclerosis M Rossato, AJ Affandi, S Thordardottir, CGK Wichers, M Cossu, ... Arthritis & rheumatology 69 (9), 1891-1902, 2017 | 70 | 2017 |
Unraveling the genetic component of systemic sclerosis JE Martín, L Bossini-Castillo, J Martín Human genetics 131, 1023-1037, 2012 | 68 | 2012 |
Genetics of systemic sclerosis L Bossini-Castillo, E López-Isac, MD Mayes, J Martín Seminars in immunopathology 37, 443-451, 2015 | 66 | 2015 |
A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells R Nasrallah, CJ Imianowski, L Bossini-Castillo, FM Grant, M Dogan, ... Nature 583 (7816), 447-452, 2020 | 50 | 2020 |