| Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models ML Schulte, A Fu, P Zhao, J Li, L Geng, ST Smith, J Kondo, RJ Coffey, ... Nature medicine 24 (2), 194-202, 2018 | 385 | 2018 |
| The discovery and characterization of ML218: a novel, centrally active T-type calcium channel inhibitor with robust effects in STN neurons and in a rodent model of Parkinson’s … Z Xiang, AD Thompson, JT Brogan, ML Schulte, BJ Melancon, D Mi, ... ACS chemical neuroscience 2 (12), 730-742, 2011 | 119 | 2011 |
| 2-Amino-4-bis (aryloxybenzyl) aminobutanoic acids: A novel scaffold for inhibition of ASCT2-mediated glutamine transport ML Schulte, AB Khodadadi, ML Cuthbertson, JA Smith, HC Manning Bioorganic & medicinal chemistry letters 26 (3), 1044-1047, 2016 | 71 | 2016 |
| Highly diastereoselective and general synthesis of primary β-fluoroamines ML Schulte, CW Lindsley Organic letters 13 (20), 5684-5687, 2011 | 60 | 2011 |
| Substituted indoles as selective protease activated receptor 4 (PAR-4) antagonists: Discovery and SAR of ML354 W Wen, SE Young, MT Duvernay, ML Schulte, KD Nance, BJ Melancon, ... Bioorganic & medicinal chemistry letters 24 (19), 4708-4713, 2014 | 48 | 2014 |
| 2-Substituted Nγ-glutamylanilides as novel probes of ASCT2 with improved potency ML Schulte, ES Dawson, SA Saleh, ML Cuthbertson, HC Manning Bioorganic & medicinal chemistry letters 25 (1), 113-116, 2015 | 43 | 2015 |
| Mutant KRAS exosomes alter the metabolic state of recipient colonic epithelial cells Q Zhang, DK Jeppesen, JN Higginbotham, MD Beckler, EJ Poulin, ... Cellular and Molecular Gastroenterology and Hepatology 5 (4), 627-629. e6, 2018 | 40 | 2018 |
| Synthesis of indole derived protease-activated receptor 4 antagonists and characterization in human platelets SE Young, MT Duvernay, ML Schulte, CW Lindsley, HE Hamm PLoS One 8 (6), e65528, 2013 | 36 | 2013 |
| Combined blockade of EGFR and glutamine metabolism in preclinical models of colorectal cancer AS Cohen, L Geng, P Zhao, A Fu, ML Schulte, R Graves-Deal, ... Translational oncology 13 (10), 100828, 2020 | 33 | 2020 |
| General Access to Chiral N-Alkyl Terminal Aziridines via Organocatalysis OO Fadeyi, ML Schulte, CW Lindsley Organic Letters 12 (14), 3276-3278, 2010 | 33 | 2010 |
| Total Synthesis of Stemaphylline N-oxide and Related C9a-Epimeric Analogs ML Schulte, ML Turlington, SS Phatak, JM Harp, SR Stauffer, CW Lindsley Chemistry (Weinheim an der Bergstrasse, Germany) 19 (36), 11847, 2013 | 30 | 2013 |
| Non-Invasive Glutamine PET Reflects Pharmacological Inhibition of BRAFV600E In Vivo ML Schulte, MR Hight, GD Ayers, Q Liu, Y Shyr, MK Washington, ... Molecular imaging and biology 19, 421-428, 2017 | 27 | 2017 |
| A general, enantioselective synthesis of 1-azabicyclo [mn 0] alkane ring systems TJ Senter, ML Schulte, LC Konkol, TE Wadzinski, CW Lindsley Tetrahedron letters 54 (13), 1645-1648, 2013 | 23 | 2013 |
| Synthetic adjuvants for vaccine formulations: Evaluation of new phytol derivatives in induction and persistence of specific immune response Y Aachoui, ML Schulte, RW Fitch, SK Ghosh Cellular Immunology 271 (2), 308-318, 2011 | 23 | 2011 |
| Dendrimer-2PMPA delays muscle function loss and denervation in a murine model of amyotrophic lateral sclerosis C Tallon, A Sharma, Z Zhang, AG Thomas, J Ng, X Zhu, A Donoghue, ... Neurotherapeutics 19 (1), 274-288, 2022 | 15 | 2022 |
| A novel and selective PAR4 antagonist: ML354 SE Young, MT Duvernay, ML Schulte, KD Nance, BJ Melancon, J Engers, ... Probe Reports from the NIH Molecular Libraries Program [Internet], 2015 | 14 | 2015 |
| Microwave-assisted, one-pot reaction of 7-azaindoles and aldehydes: a facile route to novel di-7-azaindolylmethanes MI Uddin, JR Buck, ML Schulte, D Tang, SA Saleh, YY Cheung, J Harp, ... Tetrahedron letters 55 (1), 169-173, 2014 | 12 | 2014 |
| Optimized translocator protein ligand for optical molecular imaging and screening J Li, JA Smith, ES Dawson, A Fu, ML Nickels, ML Schulte, HC Manning Bioconjugate Chemistry 28 (4), 1016-1023, 2017 | 10 | 2017 |
| Beta cell imaging—From pre-clinical validation to first in man testing S Demine, ML Schulte, PR Territo, DL Eizirik International journal of molecular sciences 21 (19), 7274, 2020 | 9 | 2020 |
| New structure–activity relationships of N-acetamide substituted pyrazolopyrimidines as pharmacological ligands of TSPO J Li, ML Schulte, ML Nickels, HC Manning Bioorganic & medicinal chemistry letters 26 (15), 3472-3477, 2016 | 9 | 2016 |
