The hyperdynamic circulation of chronic liver diseases: from the patient to the molecule Y Iwakiri, RJ Groszmann Hepatology 43 (S1), S121-S131, 2006 | 797 | 2006 |
Akt1/protein kinase Bα is critical for ischemic and VEGF-mediated angiogenesis E Ackah, J Yu, S Zoellner, Y Iwakiri, C Skurk, R Shibata, N Ouchi, ... The Journal of clinical investigation 115 (8), 2119-2127, 2005 | 471 | 2005 |
Vascular endothelial dysfunction in cirrhosis Y Iwakiri, RJ Groszmann Journal of hepatology 46 (5), 927-934, 2007 | 432 | 2007 |
Pathophysiology of portal hypertension Y Iwakiri, RJ Groszmann The Liver: Biology and Pathobiology, 659-669, 2020 | 382 | 2020 |
Vascular pathobiology in chronic liver disease and cirrhosis–current status and future directions Y Iwakiri, V Shah, DC Rockey Journal of hepatology 61 (4), 912-924, 2014 | 346 | 2014 |
Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease C Fernández-Hernando, E Ackah, J Yu, Y Suárez, T Murata, Y Iwakiri, ... Cell metabolism 6 (6), 446-457, 2007 | 321 | 2007 |
Selective inhibition of tumor microvascular permeability by cavtratin blocks tumor progression in mice JP Gratton, MI Lin, J Yu, ED Weiss, ZL Jiang, TA Fairchild, Y Iwakiri, ... Cancer cell 4 (1), 31-39, 2003 | 307 | 2003 |
Nitric oxide synthase generates nitric oxide locally to regulate compartmentalized protein S-nitrosylation and protein trafficking Y Iwakiri, A Satoh, S Chatterjee, DK Toomre, CM Chalouni, D Fulton, ... Proceedings of the National Academy of Sciences 103 (52), 19777-19782, 2006 | 293 | 2006 |
Nitric oxide in liver diseases Y Iwakiri, MY Kim Trends in Pharmacological sciences 36 (8), 524-536, 2015 | 292 | 2015 |
Endothelial dysfunction in the regulation of cirrhosis and portal hypertension Y Iwakiri Liver international 32 (2), 199-213, 2012 | 269 | 2012 |
Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity K Bryniarski, W Ptak, A Jayakumar, K Püllmann, MJ Caplan, ... Journal of Allergy and Clinical Immunology 132 (1), 170-181. e9, 2013 | 249 | 2013 |
Mild increases in portal pressure upregulate vascular endothelial growth factor and endothelial nitric oxide synthase in the intestinal microcirculatory bed, leading to a … JG Abraldes, Y Iwakiri, M Loureiro-Silva, O Haq, WC Sessa, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 290 (5 …, 2006 | 243 | 2006 |
Targeting of endothelial nitric-oxide synthase to the cytoplasmic face of the Golgi complex or plasma membrane regulates Akt-versus calcium-dependent mechanisms for nitric … D Fulton, R Babbitt, S Zoellner, J Fontana, L Acevedo, TJ McCabe, ... Journal of Biological Chemistry 279 (29), 30349-30357, 2004 | 170 | 2004 |
The portal hypertension syndrome: etiology, classification, relevance, and animal models J Bosch, Y Iwakiri Hepatology international 12, 1-10, 2018 | 159 | 2018 |
eNOS-derived nitric oxide regulates endothelial barrier function through VE-cadherin and Rho GTPases A Di Lorenzo, MI Lin, T Murata, S Landskroner-Eiger, M Schleicher, ... Journal of cell science 126 (24), 5541-5552, 2013 | 156 | 2013 |
The type III inositol 1, 4, 5-trisphosphate receptor is associated with aggressiveness of colorectal carcinoma K Shibao, MJ Fiedler, J Nagata, N Minagawa, K Hirata, Y Nakayama, ... Cell calcium 48 (6), 315-323, 2010 | 155 | 2010 |
Portal hypertension in cirrhosis: Pathophysiological mechanisms and therapy Y Iwakiri, J Trebicka JHEP reports 3 (4), 100316, 2021 | 149 | 2021 |
The hepatic lymphatic vascular system: structure, function, markers, and lymphangiogenesis M Tanaka, Y Iwakiri Cellular and molecular gastroenterology and hepatology 2 (6), 733-749, 2016 | 146 | 2016 |
Cellular distribution of injected PLGA-nanoparticles in the liver JK Park, T Utsumi, YE Seo, Y Deng, A Satoh, WM Saltzman, Y Iwakiri Nanomedicine: Nanotechnology, Biology and Medicine 12 (5), 1365-1374, 2016 | 139 | 2016 |
Single-cell transcriptomics reveals zone-specific alterations of liver sinusoidal endothelial cells in cirrhosis T Su, Y Yang, S Lai, J Jeong, Y Jung, M McConnell, T Utsumi, Y Iwakiri Cellular and molecular gastroenterology and hepatology 11 (4), 1139-1161, 2021 | 131 | 2021 |