Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance S Mok, EA Ashley, PE Ferreira, L Zhu, Z Lin, T Yeo, K Chotivanich, ... Science 347 (6220), 431-435, 2015 | 496 | 2015 |
Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance C Dogovski, SC Xie, G Burgio, J Bridgford, S Mok, JM McCaw, ... PLoS biology 13 (4), e1002132, 2015 | 345 | 2015 |
The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites Z Bozdech, S Mok, G Hu, M Imwong, A Jaidee, B Russell, H Ginsburg, ... Proceedings of the National Academy of Sciences 105 (42), 16290-16295, 2008 | 297 | 2008 |
Transcriptional profiling of growth perturbations of the human malaria parasite Plasmodium falciparum G Hu, A Cabrera, M Kono, S Mok, BK Chaal, S Haase, K Engelberg, ... Nature biotechnology 28 (1), 91-98, 2010 | 266 | 2010 |
A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells A Claessens, Y Adams, A Ghumra, G Lindergard, CC Buchan, C Andisi, ... Proceedings of the National Academy of Sciences 109 (26), E1772-E1781, 2012 | 262 | 2012 |
Transcriptional variation in the malaria parasite Plasmodium falciparum N Rovira-Graells, AP Gupta, E Planet, VM Crowley, S Mok, ... Genome Research 22 (5), 925-938, 2012 | 252 | 2012 |
Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine LS Ross, SK Dhingra, S Mok, T Yeo, KJ Wicht, K Kümpornsin, ... Nature Communications 9 (1), 3314, 2018 | 217 | 2018 |
Molecular Mechanisms of Drug Resistance in Plasmodium falciparum Malaria KJ Wicht, S Mok, DA Fidock Annual Review of Microbiology 74, 431-454, 2020 | 208 | 2020 |
Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription S Mok, M Imwong, MJ Mackinnon, J Sim, R Ramadoss, P Yi, M Mayxay, ... BMC genomics 12 (1), 1, 2011 | 199 | 2011 |
Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites. F Rocamora, L Zhu, KY Liong, A Dondorp, O Miotto, S Mok, Z Bozdech PLoS pathogens 14 (3), e1006930, 2018 | 166 | 2018 |
Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance LC Mathieu, H Cox, AM Early, S Mok, Y Lazrek, JC Paquet, MP Ade, ... Elife 9, e51015, 2020 | 149 | 2020 |
Quantitative protein expression profiling reveals extensive post-transcriptional regulation and post-translational modifications in schizont-stage malaria parasites BJ Foth, N Zhang, S Mok, PR Preiser, Z Bozdech Genome biology 9 (12), 1, 2008 | 137 | 2008 |
Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness BH Stokes, SK Dhingra, K Rubiano, S Mok, J Straimer, NF Gnadig, I Deni, ... eLife 10, e66277, 2021 | 130 | 2021 |
Dynamic epigenetic regulation of gene expression during the life cycle of malaria parasite Plasmodium falciparum AP Gupta, WH Chin, L Zhu, S Mok, YH Luah, EH Lim, Z Bozdech PLoS Pathog 9 (2), e1003170, 2013 | 126 | 2013 |
Artemisinin-resistant K13 mutations rewire Plasmodium falciparum’s intra-erythrocytic metabolic program to enhance survival S Mok, BH Stokes, NF Gnädig, LS Ross, T Yeo, C Amaratunga, E Allman, ... Nature communications 12 (1), 530, 2021 | 114 | 2021 |
A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug Piperaquine SK Dhingra, D Redhi, JM Combrinck, T Yeo, J Okombo, PP Henrich, ... mBio 8 (3), e00303-17, 2017 | 105 | 2017 |
Comparative transcriptional and genomic analysis of Plasmodium falciparum field isolates MJ Mackinnon, J Li, S Mok, MM Kortok, K Marsh, PR Preiser, Z Bozdech PLoS pathogens 5 (10), e1000644, 2009 | 105 | 2009 |
New insights into the Plasmodium vivax transcriptome using RNA-Seq L Zhu, S Mok, M Imwong, A Jaidee, B Russell, F Nosten, NP Day, ... Scientific reports 6 (1), 20498, 2016 | 84 | 2016 |
Adaptation of Plasmodium falciparum to its transmission environment MK Rono, MA Nyonda, JJ Simam, JM Ngoi, S Mok, MM Kortok, ... Nature ecology & evolution 2 (2), 377-387, 2018 | 78 | 2018 |
Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13 NF Gnädig, BH Stokes, RL Edwards, GF Kalantarov, KC Heimsch, ... PLoS Pathogens 16 (4), e1008482, 2020 | 74 | 2020 |