Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1 ME Patti, AJ Butte, S Crunkhorn, K Cusi, R Berria, S Kashyap, Y Miyazaki, ... Proceedings of the national academy of sciences 100 (14), 8466-8471, 2003 | 2436 | 2003 |
Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene E Araki, MA Lipes, ME Patti, JC Brüning, B Haag III, RS Johnson, ... Nature 372 (6502), 186-190, 1994 | 1728 | 1994 |
Insulin resistance differentially affects the PI 3-kinase–and MAP kinase–mediated signaling in human muscle K Cusi, K Maezono, A Osman, M Pendergrass, ME Patti, T Pratipanawatr, ... The Journal of clinical investigation 105 (3), 311-320, 2000 | 1599 | 2000 |
Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte-specific secretory protein adiponectin TP Combs, AH Berg, MW Rajala, S Klebanov, P Iyengar, ... Diabetes 52 (2), 268-276, 2003 | 723 | 2003 |
Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism ME Patti, SM Houten, AC Bianco, R Bernier, PR Larsen, JJ Holst, ... Obesity 17 (9), 1671-1677, 2009 | 702 | 2009 |
In utero undernourishment perturbs the adult sperm methylome and intergenerational metabolism EJ Radford, M Ito, H Shi, JA Corish, K Yamazawa, E Isganaitis, ... Science 345 (6198), 1255903, 2014 | 682 | 2014 |
The role of mitochondria in the pathogenesis of type 2 diabetes ME Patti, S Corvera Endocrine reviews 31 (3), 364-395, 2010 | 664 | 2010 |
Bidirectional modulation of insulin action by amino acids. ME Patti, E Brambilla, L Luzi, EJ Landaker, CR Kahn The Journal of clinical investigation 101 (7), 1519-1529, 1998 | 603 | 1998 |
Patients with neuroglycopenia after gastric bypass surgery have exaggerated incretin and insulin secretory responses to a mixed meal AB Goldfine, EC Mun, E Devine, R Bernier, M Baz-Hecht, DB Jones, ... The Journal of Clinical Endocrinology & Metabolism 92 (12), 4678-4685, 2007 | 444 | 2007 |
Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia ME Patti, G McMahon, EC Mun, A Bitton, JJ Holst, J Goldsmith, DW Hanto, ... Diabetologia 48, 2236-2240, 2005 | 412 | 2005 |
The emerging genetic architecture of type 2 diabetes A Doria, ME Patti, CR Kahn Cell metabolism 8 (3), 186-200, 2008 | 405 | 2008 |
Intergenerational transmission of glucose intolerance and obesity by in utero undernutrition in mice JC Jimenez-Chillaron, E Isganaitis, M Charalambous, S Gesta, ... Diabetes 58 (2), 460-468, 2009 | 370 | 2009 |
Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle. ME Patti, A Virkamäki, EJ Landaker, CR Kahn, H Yki-Järvinen Diabetes 48 (8), 1562-1571, 1999 | 350 | 1999 |
Metabolic effects of sodium metavanadate in humans with insulin-dependent and noninsulin-dependent diabetes mellitus in vivo and in vitro studies AB Goldfine, DC Simonson, F Folli, ME Patti, CR Kahn The Journal of Clinical Endocrinology & Metabolism 80 (11), 3311-3320, 1995 | 330 | 1995 |
4ps/insulin receptor substrate (irs)-2 is the alternative substrate of the insulin receptor in irs-1-deficient mice (∗) ME Patti, XJ Sun, JC Bruening, E Araki, MA Lipes, MF White, CR Kahn Journal of Biological Chemistry 270 (42), 24670-24673, 1995 | 302 | 1995 |
Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin YH Tseng, AJ Butte, E Kokkotou, VK Yechoor, CM Taniguchi, ... Nature cell biology 7 (6), 601-611, 2005 | 277 | 2005 |
Peroxisome proliferator activator receptor γ coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated … S Crunkhorn, F Dearie, C Mantzoros, H Gami, WS da Silva, D Espinoza, ... Journal of Biological Chemistry 282 (21), 15439-15450, 2007 | 273 | 2007 |
Metabolic effects of vanadyl sulfate in humans with non—insulin-dependent diabetes mellitus: in vivo and in vitro studies AB Goldfine, ME Patti, L Zuberi, BJ Goldstein, R LeBlanc, EJ Landaker, ... Metabolism 49 (3), 400-410, 2000 | 263 | 2000 |
Epigenetic mechanisms of transmission of metabolic disease across generations VM Sales, AC Ferguson-Smith, ME Patti Cell metabolism 25 (3), 559-571, 2017 | 232 | 2017 |
The insulin receptor-a critical link in glucose homeostasis and insulin action ME Patti, CR Kahn Journal of basic and clinical physiology and pharmacology 9 (2-4), 89-110, 1998 | 227 | 1998 |