Curcumin Attenuates Amyloid-β Aggregate Toxicity and Modulates Amyloid-β Aggregation Pathway A Thapa, SD Jett, EY Chi ACS Chemical Neuroscience 7 (1), 56-68, 2016 | 168 | 2016 |
Biflavonoids are superior to monoflavonoids in inhibiting amyloid-β toxicity and fibrillogenesis via accumulation of nontoxic oligomer-like structures A Thapa, ER Woo, EY Chi, MG Sharoar, HG Jin, SY Shin, IS Park Biochemistry 50 (13), 2445-2455, 2011 | 123 | 2011 |
Dietary modulation of oxidative stress in Alzheimer’s disease A Thapa, NJ Carroll International journal of molecular sciences 18 (7), 1583, 2017 | 97 | 2017 |
The Nlrp3 inflammasome as a “rising star” in studies of normal and malignant hematopoiesis MZ Ratajczak, K Bujko, M Cymer, A Thapa, M Adamiak, J Ratajczak, ... Leukemia 34 (6), 1512-1523, 2020 | 86 | 2020 |
cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel function J Xu, L Morris, A Thapa, H Ma, S Michalakis, M Biel, W Baehr, ... Journal of Neuroscience 33 (37), 14939-14948, 2013 | 83 | 2013 |
Keampferol-3-O-rhamnoside abrogates amyloid beta toxicity by modulating monomers and remodeling oligomers and fibrils to non-toxic aggregates MG Sharoar, A Thapa, M Shahnawaz, VS Ramasamy, ER Woo, SY Shin, ... Journal of biomedical science 19, 1-13, 2012 | 81 | 2012 |
Therapeutic Genome Editing for Myotonic Dystrophy Type 1 Using CRISPR/Cas9 XG Wang Y, Hao L, Wang H, Santostefano K, Thapa A, Cleary J, Li H, Guo X ... Mol Ther. 26 (11), 2617-2630, 2018 | 66 | 2018 |
Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration H Ma, A Thapa, L Morris, TM Redmond, W Baehr, XQ Ding Proceedings of the National Academy of Sciences 111 (9), 3602-3607, 2014 | 65 | 2014 |
Membrane-mediated neuroprotection by curcumin from amyloid-β-peptide-induced toxicity A Thapa, BC Vernon, K De la Pena, G Soliz, HA Moreno, GP López, ... Langmuir 29 (37), 11713-11723, 2013 | 62 | 2013 |
Purification of Inclusion Body—Forming Peptides and Proteins in Soluble form by Fusion to Escherichia Coli Thermostable Proteins A Thapa, M Shahnawaz, P Karki, G Raj Dahal, M Golam Sharoar, ... Biotechniques 44 (6), 787-796, 2008 | 61 | 2008 |
The Nlrp3 inflammasome orchestrates mobilization of bone marrow-residing stem cells into peripheral blood AM Lenkiewicz, M Adamiak, A Thapa, K Bujko, D Pedziwiatr, ... Stem Cell Reviews and Reports 15, 391-403, 2019 | 59 | 2019 |
Endoplasmic reticulum stress-associated cone photoreceptor degeneration in cyclic nucleotide-gated channel deficiency A Thapa, L Morris, J Xu, H Ma, S Michalakis, M Biel, XQ Ding Journal of Biological Chemistry 287 (22), 18018-18029, 2012 | 55 | 2012 |
NLRP3 inflammasome couples purinergic signaling with activation of the complement cascade for the optimal release of cells from bone marrow MZ Ratajczak, M Adamiak, A Thapa, K Bujko, K Brzezniakiewicz-Janus, ... Leukemia 33 (4), 815-825, 2019 | 54 | 2019 |
Stable activity of a deubiquitylating enzyme (Usp2-cc) in the presence of high concentrations of urea and its application to purify aggregation-prone peptides M Shahnawaz, A Thapa, IS Park Biochemical and biophysical research communications 359 (3), 801-805, 2007 | 53 | 2007 |
Biflavonoids as potential small molecule therapeutics for Alzheimer’s disease A Thapa, EY Chi Natural compounds as therapeutic agents for amyloidogenic diseases, 55-77, 2015 | 43 | 2015 |
Nlrp3 inflammasome signaling regulates the homing and engraftment of hematopoietic stem cells (HSPCs) by enhancing incorporation of CXCR4 receptor into membrane lipid rafts M Adamiak, A Abdel-Latif, K Bujko, A Thapa, K Anusz, M Tracz, ... Stem Cell Reviews and Reports 16, 954-967, 2020 | 41 | 2020 |
cGMP/protein kinase G signaling suppresses inositol 1, 4, 5-trisphosphate receptor phosphorylation and promotes endoplasmic reticulum stress in photoreceptors of cyclic … H Ma, MR Butler, A Thapa, J Belcher, F Yang, W Baehr, M Biel, ... Journal of Biological Chemistry 290 (34), 20880-20892, 2015 | 39 | 2015 |
High Selectivity and Sensitivity of Oligomeric p-Phenylene Ethynylenes for Detecting Fibrillar and Prefibrillar Amyloid Protein Aggregates AM Fanni, FA Monge, CY Lin, A Thapa, K Bhaskar, DG Whitten, EY Chi ACS Chemical Neuroscience 10 (3), 1813-1825, 2019 | 33 | 2019 |
Loss of cone cyclic nucleotide-gated channel leads to alterations in light response modulating system and cellular stress response pathways: a gene expression profiling study H Ma, A Thapa, LM Morris, S Michalakis, M Biel, MB Frank, M Bebak, ... Human molecular genetics 22 (19), 3906-3919, 2013 | 31 | 2013 |
Status paper on road safety in Nepal AJ Thapa DDG, Department of Roads. Kathmandu, Nepal 22, 2013 | 30 | 2013 |