Treponema pallidum TroA is a periplasmic zinc-binding protein with a helical backbone YH Lee, RK Deka, MV Norgard, JD Radolf, CA Hasemann Nature structural biology 6 (7), 628-633, 1999 | 207 | 1999 |
Structure of the proline dehydrogenase domain of the multifunctional PutA flavoprotein YH Lee, S Nadaraia, D Gu, DF Becker, JJ Tanner nature structural biology 10 (2), 109-114, 2003 | 127 | 2003 |
The Crystal Structure of Zn(II)-Free Treponema pallidum TroA, a Periplasmic Metal-Binding Protein, Reveals a Closed Conformation YH Lee, MR Dorwart, KRO Hazlett, RK Deka, MV Norgard, JD Radolf, ... Journal of bacteriology 184 (8), 2300-2304, 2002 | 115 | 2002 |
Structure-based development of small molecule PFKFB3 inhibitors: a framework for potential cancer therapeutic agents targeting the Warburg effect M Seo, JD Kim, D Neau, I Sehgal, YH Lee PloS one 6 (9), e24179, 2011 | 94 | 2011 |
Crystal structure of the hypoxia-inducible form of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase (PFKFB3): a possible new target for cancer therapy SG Kim, NP Manes, MR El-Maghrabi, YH Lee Journal of Biological Chemistry 281 (5), 2939-2944, 2006 | 75 | 2006 |
PFKFB3 regulates oxidative stress homeostasis via its S-glutathionylation in cancer M Seo, YH Lee Journal of molecular biology 426 (4), 830-842, 2014 | 66 | 2014 |
Crystal Structure of the Rat Liver Fructose-2,6-bisphosphatase Based on Selenomethionine Multiwavelength Anomalous Dispersion Phases, YH Lee, C Ogata, JW Pflugrath, DG Levitt, R Sarma, LJ Banaszak, ... Biochemistry 35 (19), 6010-6019, 1996 | 61 | 1996 |
Effect of mutations on the sensitivity of human beta-cell glucokinase to liver regulatory protein M Veiga-da-Cunha, LZ Xu, YH Lee, D Marotta, SJ Pilkis, ... Diabetologia 39, 1173-1179, 1996 | 56 | 1996 |
Crystal structure of Dps-1, a functionally distinct Dps protein from Deinococcus radiodurans SG Kim, G Bhattacharyya, A Grove, YH Lee Journal of molecular biology 361 (1), 105-114, 2006 | 55 | 2006 |
Tissue-specific structure/function differentiation of the liver isoform of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase YH Lee, Y Li, K Uyeda, CA Hasemann Journal of Biological Chemistry 278 (1), 523-530, 2003 | 49 | 2003 |
Mechanism for attenuation of DNA binding by MarR family transcriptional regulators by small molecule ligands IC Perera, YH Lee, SP Wilkinson, A Grove Journal of molecular biology 390 (5), 1019-1029, 2009 | 44 | 2009 |
Crystal structure of the H256A mutant of rat testis fructose-6-phosphate, 2-kinase/fructose-2, 6-bisphosphatase: fructose 6-phosphate in the active site leads to mechanisms for … MH Yuen, H Mizuguchi, YH Lee, PF Cook, K Uyeda, CA Hasemann Journal of Biological Chemistry 274 (4), 2176-2184, 1999 | 41 | 1999 |
Molecular basis of the fructose‐2, 6‐bisphosphatase reaction of PFKFB3: Transition state and the C‐terminal function MC Cavalier, SG Kim, D Neau, YH Lee Proteins: Structure, Function, and Bioinformatics 80 (4), 1143-1153, 2012 | 38 | 2012 |
Crystal structure of a trapped phosphoenzyme during a catalytic reaction YH Lee, TW Olson, CM Ogata, DG Levitt, LJ Banaszak, AJ Lange Nature Structural Biology 4 (8), 615-618, 1997 | 37 | 1997 |
Physicochemical Evidence that Treponema pallidum TroA Is a Zinc-Containing Metalloprotein That Lacks Porin-Like Structure RK Deka, YH Lee, KE Hagman, D Shevchenko, CA Lingwood, ... Journal of bacteriology 181 (14), 4420-4423, 1999 | 35 | 1999 |
Flavin nucleotides act as electron shuttles mediating reduction of the [2Fe-2S] clusters in mitochondrial outer membrane protein mitoNEET AP Landry, Y Wang, Z Cheng, RB Crochet, YH Lee, H Ding Free Radic Biol Med 102, 240-247, 2016 | 27 | 2016 |
A Direct Substrate–Substrate Interaction Found in the Kinase Domain of the Bifunctional Enzyme, 6-Phosphofructo-2-kinase/Fructose-2, 6-bisphosphatase SG Kim, M Cavalier, MR El-Maghrabi, YH Lee Journal of molecular biology 370 (1), 14-26, 2007 | 27 | 2007 |
Crystal structure of heart 6‐phosphofructo‐2‐kinase/fructose‐2, 6‐bisphosphatase (PFKFB2) and the inhibitory influence of citrate on substrate binding RB Crochet, JD Kim, H Lee, YS Yim, SG Kim, D Neau, YH Lee Proteins: Structure, Function, and Bioinformatics 85 (1), 117-124, 2017 | 26 | 2017 |
Administering plasmid DNA encoding tumor vessel-anchored IFN-alpha for localizing gene product within or into tumors S Craig, R., Cutrera, J., Zhu, S., Xia, X., Lee, Y.-H., and Li Mol Ther 16, 901-6, 2008 | 26 | 2008 |
Crystal structure of a high-affinity variant of rat α-parvalbumin YH Lee, JJ Tanner, JD Larson, MT Henzl Biochemistry 43 (31), 10008-10017, 2004 | 22 | 2004 |