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Christophe Le Tourneau
Christophe Le Tourneau
Institut Curie
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Pembrolizumab versus methotrexate, docetaxel, or cetuximab for recurrent or metastatic head-and-neck squamous cell carcinoma (KEYNOTE-040): a randomised, open-label, phase 3 study
EEW Cohen, D Soulières, C Le Tourneau, J Dinis, L Licitra, MJ Ahn, ...
The Lancet 393 (10167), 156-167, 2019
14382019
Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy
CH Ries, MA Cannarile, S Hoves, J Benz, K Wartha, V Runza, ...
Cancer cell 25 (6), 846-859, 2014
13442014
Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept …
C Le Tourneau, JP Delord, A Gonçalves, C Gavoille, C Dubot, N Isambert, ...
The lancet oncology 16 (13), 1324-1334, 2015
10992015
Dose escalation methods in phase I cancer clinical trials
C Le Tourneau, JJ Lee, LL Siu
JNCI: Journal of the National Cancer Institute 101 (10), 708-720, 2009
9792009
Hyperprogression during anti-PD-1/PD-L1 therapy in patients with recurrent and/or metastatic head and neck squamous cell carcinoma
E Saâda-Bouzid, C Defaucheux, A Karabajakian, VP Coloma, V Servois, ...
Annals of Oncology 28 (7), 1605-1611, 2017
6062017
Genomic characterization of metastatic breast cancers
F Bertucci, CKY Ng, A Patsouris, N Droin, S Piscuoglio, N Carbuccia, ...
Nature 569 (7757), 560-564, 2019
5832019
Safety and efficacy of pembrolizumab in advanced, programmed death ligand 1–positive cervical cancer: results from the phase Ib KEYNOTE-028 trial
JS Frenel, C Le Tourneau, B O’Neil, PA Ott, SA Piha-Paul, C Gomez-Roca, ...
Journal of Clinical Oncology 35 (36), 4035-4041, 2017
4682017
Novel patterns of response under immunotherapy
E Borcoman, Y Kanjanapan, S Champiat, S Kato, V Servois, R Kurzrock, ...
Annals of Oncology 30 (3), 385-396, 2019
4622019
Safety and antitumor activity of pembrolizumab in patients with programmed death-ligand 1–positive nasopharyngeal carcinoma: results of the KEYNOTE-028 study
C Hsu, SH Lee, S Ejadi, C Even, RB Cohen, C Le Tourneau, JM Mehnert, ...
Journal of Clinical Oncology 35 (36), 4050-4056, 2017
4312017
Mutational profile of metastatic breast cancers: a retrospective analysis
C Lefebvre, T Bachelot, T Filleron, M Pedrero, M Campone, JC Soria, ...
PLoS medicine 13 (12), e1002201, 2016
3812016
CSF1R inhibition with emactuzumab in locally advanced diffuse-type tenosynovial giant cell tumours of the soft tissue: a dose-escalation and dose-expansion phase 1 study
PA Cassier, A Italiano, CA Gomez-Roca, C Le Tourneau, M Toulmonde, ...
The Lancet Oncology 16 (8), 949-956, 2015
3602015
Safety and antitumor activity of pembrolizumab in patients with estrogen receptor–positive/human epidermal growth factor receptor 2–negative advanced breast cancer
HS Rugo, JP Delord, SA Im, PA Ott, SA Piha-Paul, PL Bedard, J Sachdev, ...
Clinical Cancer Research 24 (12), 2804-2811, 2018
3262018
Circulating tumor DNA as a non-invasive substitute to metastasis biopsy for tumor genotyping and personalized medicine in a prospective trial across all tumor types
R Lebofsky, C Decraene, V Bernard, M Kamal, A Blin, Q Leroy, TR Frio, ...
Molecular oncology 9 (4), 783-790, 2015
2942015
Sunitinib: a novel tyrosine kinase inhibitor. A brief review of its therapeutic potential in the treatment of renal carcinoma and gastrointestinal stromal tumors (GIST)
C Le Tourneau, E Raymond, S Faivre
Therapeutics and clinical risk management 3 (2), 341-348, 2007
2572007
Patterns of response and progression to immunotherapy
E Borcoman, A Nandikolla, G Long, S Goel, C Le Tourneau
American Society of Clinical Oncology Educational Book 38, 169-178, 2018
2552018
Outcome and molecular landscape of patients with PIK3CA-mutated metastatic breast cancer
F Mosele, B Stefanovska, A Lusque, AT Dien, I Garberis, N Droin, ...
Annals of Oncology 31 (3), 377-386, 2020
2542020
FDG PET/CT for assessing tumour response to immunotherapy: Report on the EANM symposium on immune modulation and recent review of the literature
N Aide, RJ Hicks, C Le Tourneau, S Lheureux, S Fanti, E Lopci
European journal of nuclear medicine and molecular imaging 46, 238-250, 2019
2292019
Phase I evaluation of seliciclib (R-roscovitine), a novel oral cyclin-dependent kinase inhibitor, in patients with advanced malignancies
C Le Tourneau, S Faivre, V Laurence, C Delbaldo, K Vera, V Girre, ...
European journal of cancer 46 (18), 3243-3250, 2010
1872010
Pembrolizumab for the treatment of advanced salivary gland carcinoma: findings of the phase 1b KEYNOTE-028 study
RB Cohen, JP Delord, T Doi, SA Piha-Paul, SV Liu, J Gilbert, AP Algazi, ...
American journal of clinical oncology 41 (11), 1083-1088, 2018
1802018
Avelumab in patients with previously treated metastatic adrenocortical carcinoma: phase 1b results from the JAVELIN solid tumor trial
C Le Tourneau, C Hoimes, C Zarwan, DJ Wong, S Bauer, R Claus, ...
Journal for immunotherapy of cancer 6, 1-9, 2018
1562018
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