Spontaneous transformation of human adult nontumorigenic stem cells to cancer stem cells is driven by genomic instability in a human model of glioblastoma A Shiras, ST Chettiar, V Shepal, G Rajendran, GR Prasad, P Shastry Stem Cells 25 (6), 1478-1489, 2007 | 216 | 2007 |
Separation of circadian-and behavior-driven metabolite rhythms in humans provides a window on peripheral oscillators and metabolism DJ Skene, E Skornyakov, NR Chowdhury, RP Gajula, B Middleton, ... Proceedings of the National Academy of Sciences 115 (30), 7825-7830, 2018 | 170 | 2018 |
MORC2 signaling integrates phosphorylation-dependent, ATPase-coupled chromatin remodeling during the DNA damage response DQ Li, SS Nair, K Ohshiro, A Kumar, VS Nair, SB Pakala, SDN Reddy, ... Cell reports 2 (6), 1657-1669, 2012 | 136 | 2012 |
TWIST1-WDR5-Hottip Regulates Hoxa9 Chromatin to Facilitate Prostate Cancer Metastasis R Malek, RP Gajula, RD Williams, B Nghiem, BW Simons, K Nugent, ... Cancer research 77 (12), 3181-3193, 2017 | 124 | 2017 |
The twist box domain is required for Twist1-induced prostate cancer metastasis RP Gajula, ST Chettiar, RD Williams, S Thiyagarajan, Y Kato, K Aziz, ... Molecular cancer research 11 (11), 1387-1400, 2013 | 90 | 2013 |
Inhibition of TWIST1 Leads to Activation of Oncogene-Induced Senescence in Oncogene-Driven Non–Small Cell Lung Cancer TF Burns, I Dobromilskaya, SC Murphy, RP Gajula, S Thiyagarajan, ... Molecular Cancer Research 11 (4), 329-338, 2013 | 72 | 2013 |
Night shift schedule causes circadian dysregulation of DNA repair genes and elevated DNA damage in humans BSC Koritala, KI Porter, OA Arshad, RP Gajula, HD Mitchell, T Arman, ... Journal of pineal research 70 (3), e12726, 2021 | 69 | 2021 |
The circadian clock regulates cisplatin-induced toxicity and tumor regression in melanoma mouse and human models PP Dakup, KI Porter, AA Little, RP Gajula, H Zhang, E Skornyakov, ... Oncotarget 9 (18), 14524, 2018 | 61 | 2018 |
Novel Hsp90 inhibitor NVP-AUY922 radiosensitizes prostate cancer cells N Gandhi, AT Wild, ST Chettiar, K Aziz, Y Kato, RP Gajula, RD Williams, ... Cancer biology & therapy 14 (4), 347-356, 2013 | 51 | 2013 |
Hedgehog pathway inhibition radiosensitizes non-small cell lung cancers J Zeng, K Aziz, ST Chettiar, BT Aftab, M Armour, R Gajula, N Gandhi, ... International Journal of Radiation Oncology* Biology* Physics 86 (1), 143-149, 2013 | 50 | 2013 |
Concurrent versus sequential sorafenib therapy in combination with radiation for hepatocellular carcinoma AT Wild, N Gandhi, ST Chettiar, K Aziz, RP Gajula, RD Williams, R Kumar, ... PloS one 8 (6), e65726, 2013 | 42 | 2013 |
Nelfinavir induces radiation sensitization in pituitary adenoma cells J Zeng, AP See, K Aziz, S Thiyagarajan, T Salih, RP Gajula, M Armour, ... Cancer biology & therapy 12 (7), 657-663, 2011 | 37 | 2011 |
MicroRNAs and cancer therapy: the next wave or here to stay? SDN Reddy, RP Gajula, SB Pakala, R Kumar Cancer biology & therapy 9 (7), 479-482, 2010 | 37 | 2010 |
Noncoding RNA Ginir functions as an oncogene by associating with centrosomal proteins S Panda, M Setia, N Kaur, V Shepal, V Arora, DK Singh, A Mondal, A Teli, ... PLoS biology 16 (10), e2004204, 2018 | 32 | 2018 |
Structure-function studies of the bHLH phosphorylation domain of TWIST1 in prostate cancer cells RP Gajula, ST Chettiar, RD Williams, K Nugent, Y Kato, H Wang, R Malek, ... Neoplasia 17 (1), 16-31, 2015 | 30 | 2015 |
The circadian clock protects against ionizing radiation-induced cardiotoxicity PP Dakup, KI Porter, RP Gajula, PN Goel, Z Cheng, S Gaddameedhi FASEB journal: official publication of the Federation of American Societies …, 2020 | 26 | 2020 |
Tissue biomarkers for prostate cancer radiation therapy P T Tran, R K Hales, J Zeng, K Aziz, T Salih, R P Gajula, S Chettiar, ... Current molecular medicine 12 (6), 772-787, 2012 | 25 | 2012 |
Circadian clock protein BMAL1 regulates melanogenesis through MITF in melanoma cells S Sarkar, KI Porter, PP Dakup, RP Gajula, BSC Koritala, R Hylton, ... Pigment cell & melanoma research 34 (5), 955-965, 2021 | 20 | 2021 |
Commentary: Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure RP Gajula, S Gaddameedhi Frontiers in Physiology 6, 276, 2015 | 11 | 2015 |
A twist1-MLL-WDR5-HOTTIP complex regulates HOXA9 chromatin to facilitate metastasis of prostate cancer PT Tran, R Gajula, R Williams, R Malek, K Nugent, A Walker, S Chettiar, ... International Journal of Radiation Oncology, Biology, Physics 90 (1), S177, 2014 | 6 | 2014 |