| Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation J Varani, MK Dame, L Rittie, SEG Fligiel, S Kang, GJ Fisher, JJ Voorhees The American journal of pathology 168 (6), 1861-1868, 2006 | 1035 | 2006 |
| Role of endothelial-leukocyte adhesion molecule 1 (ELAM-1) in neutrophil-mediated lung injury in rats. MS Mulligan, J Varani, MK Dame, CL Lane, CW Smith, DC Anderson, ... The Journal of clinical investigation 88 (4), 1396-1406, 1991 | 490 | 1991 |
| Reduced fibroblast interaction with intact collagen as a mechanism for depressed collagen synthesis in photodamaged skin J Varani, L Schuger, MK Dame, C Leonard, SEG Fligiel, S Kang, ... Journal of Investigative Dermatology 122 (6), 1471-1479, 2004 | 226 | 2004 |
| Iron uptake via DMT1 integrates cell cycle with JAK-STAT3 signaling to promote colorectal tumorigenesis X Xue, SK Ramakrishnan, K Weisz, D Triner, L Xie, D Attili, A Pant, ... Cell metabolism 24 (3), 447-461, 2016 | 206 | 2016 |
| Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1 H Zhang, SK Ramakrishnan, D Triner, B Centofanti, D Maitra, B Győrffy, ... Science signaling 8 (397), ra98-ra98, 2015 | 199 | 2015 |
| Heparin-binding epidermal-growth-factor-like growth factor activation of keratinocyte ErbB receptors mediates epidermal hyperplasia, a prominent side-effect of retinoid therapy J Varani, M Zeigler, MK Dame, S Kang, GJ Fisher, JJ Voorhees, SW Stoll, ... Journal of investigative dermatology 117 (6), 1335-1341, 2001 | 98 | 2001 |
| Perfluorocarbon protects lung epithelial cells from neutrophil-mediated injury in an in vitro model of liquid ventilation therapy J Varani, RB Hirschl, M Dame, K Johnson Shock 6 (5), 339-344, 1996 | 95 | 1996 |
| Cyclic stretching of mesangial cells up-regulates intercellular adhesion molecule-1 and leukocyte adherence: a possible new mechanism for glomerulosclerosis BL Riser, J Varani, P Cortes, J Yee, M Dame, AK Sharba The American journal of pathology 158 (1), 11-17, 2001 | 88 | 2001 |
| Growth of three established cell lines on glass microcarriers J Carani, M Dame, TF Beals, JA Wass Biotechnology and Bioengineering 25 (5), 1359-1372, 1983 | 86 | 1983 |
| Astrovirus replication in human intestinal enteroids reveals multi-cellular tropism and an intricate host innate immune landscape AO Kolawole, C Mirabelli, DR Hill, SA Svoboda, AB Janowski, ... PLoS pathogens 15 (10), e1008057, 2019 | 84 | 2019 |
| Chronic stress and intestinal barrier dysfunction: Glucocorticoid receptor and transcription repressor HES1 regulate tight junction protein Claudin-1 promoter G Zheng, G Victor Fon, W Meixner, A Creekmore, Y Zong, M K. Dame, ... Scientific Reports 7 (1), 4502, 2017 | 80 | 2017 |
| Protection of human umbilical vein endothelial cells by glycine and structurally similar amino acids against calcium and hydrogen peroxide-induced lethal cell injury. JM Weinberg, J Varani, KJ Johnson, NF Roeser, MK Dame, JA Davis, ... The American journal of pathology 140 (2), 457, 1992 | 75 | 1992 |
| Identification, isolation and characterization of human LGR5-positive colon adenoma cells MK Dame, D Attili, SD McClintock, PH Dedhia, P Ouillette, O Hardt, ... Development 145 (6), dev153049, 2018 | 74 | 2018 |
| A Method for Cryogenic Preservation of Human Biopsies and Subsequent Organoid Culture YH Tsai∗, M Czerwinski∗, A Wu, MK Dame, D Attili, E Hill, JA Colacino, ... Cellular and Molecular Gastroenterology and Hepatology, cmgh, 2018 | 73* | 2018 |
| Human umbilical vein endothelial cell killing by activated neutrophils. Loss of sensitivity to injury is accompanied by decreased iron content during in vitro culture and is … J Varani, MK Dame, DF Gibbs, CG Taylor, JM Weinberg, J Shayevitz, ... Laboratory Investigation; a Journal of Technical Methods and Pathology 66 (6 …, 1992 | 73 | 1992 |
| Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells AJ Schwartz, JW Goyert, S Solanki, SA Kerk, B Chen, C Castillo, PP Hsu, ... Nature metabolism 3 (7), 969-982, 2021 | 71 | 2021 |
| Heterogeneity of vascular endothelial cells: differences in susceptibility to neutrophil-mediated injury HS Murphy, N Bakopoulos, MK Dame, J Varani, PA Ward Microvascular research 56 (3), 203-211, 1998 | 66 | 1998 |
| Fibroblast response to lanthanoid metal ion stimulation: potential contribution to fibrotic tissue injury W Jenkins, P Perone, K Walker, N Bhagavathula, MN Aslam, M DaSilva, ... Biological trace element research 144, 621-635, 2011 | 57 | 2011 |
| Human colonic crypts in culture: segregation of immunochemical markers in normal versus adenoma-derived MK Dame, Y Jiang, HD Appelman, KD Copley, SD McClintock, MN Aslam, ... Laboratory investigation 94 (2), 222-234, 2014 | 56 | 2014 |
| Substrate-dependent differences in growth and biological properties of fibroblasts and epithelial cells grown in microcarrier culture J Varani, M Dame, J Rediske, TF Beals, W Hillegas Journal of Biological Standardization 13 (1), 67-76, 1985 | 54 | 1985 |
James VaraniUniversity of MichiganVerified email at med.umich.edu
