Anionic nanoparticles enable the oral delivery of proteins by enhancing intestinal permeability NG Lamson, A Berger, KC Fein, KA Whitehead Nature biomedical engineering 4 (1), 84-96, 2020 | 235 | 2020 |
Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery N Boehnke, JP Straehla, HC Safford, M Kocak, MG Rees, M Ronan, ... Science 377 (6604), eabm5551, 2022 | 111 | 2022 |
A Potent Branched-Tail Lipid Nanoparticle Enables Multiplexed mRNA Delivery and Gene Editing In Vivo KA Hajj, JR Melamed, N Chaudhary, NG Lamson, RL Ball, SS Yerneni, ... Nano letters 20 (7), 5167-5175, 2020 | 102 | 2020 |
Expanding the utility of the dextran sulfate sodium (DSS) mouse model to induce a clinically relevant loss of intestinal barrier function KE Cochran, NG Lamson, KA Whitehead PeerJ 8, e8681, 2020 | 36 | 2020 |
The pH of piperazine derivative solutions predicts their utility as transepithelial permeation enhancers NG Lamson, G Cusimano, K Suri, A Zhang, KA Whitehead Molecular Pharmaceutics 13 (2), 578-585, 2016 | 28 | 2016 |
Structure-function analysis of phenylpiperazine derivatives as intestinal permeation enhancers KC Fein, NG Lamson, KA Whitehead Pharmaceutical Research 34, 1320-1329, 2017 | 24 | 2017 |
Thrifty, rapid intestinal monolayers (TRIM) using caco-2 epithelial cells for oral drug delivery experiments NG Lamson, RL Ball, KC Fein, KA Whitehead Pharmaceutical Research 36, 1-12, 2019 | 15 | 2019 |
The strawberry-derived permeation enhancer pelargonidin enables oral protein delivery NG Lamson, KC Fein, JP Gleeson, AN Newby, S Xian, K Cochran, ... Proceedings of the National Academy of Sciences 119 (33), e2207829119, 2022 | 14 | 2022 |
Reversible inhibition of efflux transporters by hydrogel microdevices ES Levy, KE Samy, NG Lamson, KA Whitehead, DL Kroetz, TA Desai European Journal of Pharmaceutics and Biopharmaceutics 145, 76-84, 2019 | 14 | 2019 |
Piperazine derivatives enhance epithelial cell monolayer permeability by increased cell force generation and loss of cadherin structures S Zheng, K Lavrenyuk, NG Lamson, KC Fein, KA Whitehead, KN Dahl ACS Biomaterials Science & Engineering 6 (1), 367-374, 2019 | 12 | 2019 |
Long‐term daily oral administration of intestinal permeation enhancers is safe and effective in mice KC Fein, JP Gleeson, K Cochran, NG Lamson, R Doerfler, JR Melamed, ... Bioengineering & Translational Medicine 8 (1), e10342, 2023 | 8 | 2023 |
Layer-by-layer polymer functionalization improves nanoparticle penetration and glioblastoma targeting in the brain AJ Pickering, NG Lamson, MH Marand, W Hwang, JP Straehla, ... ACS nano 17 (23), 24154-24169, 2023 | 7 | 2023 |
Method of increasing epithelial permeability using nanoparticles KA Whitehead, NG Lamson US Patent App. 16/630,219, 2020 | 4 | 2020 |
Core material and surface chemistry of Layer-by-Layer (LbL) nanoparticles independently direct uptake, transport, and trafficking in preclinical blood-brain barrier (BBB) models NG Lamson, AJ Pickering, J Wyckoff, P Ganesh, JP Straehla, ... bioRxiv, 2022.10. 31.514595, 2022 | 3 | 2022 |
From farm to pharmacy: strawberry-enabled oral delivery of protein drugs NG Lamson, KC Fein, JP Gleeson, S Xian, A Newby, N Chaudhary, ... bioRxiv, 2020.03. 11.987461, 2020 | 3 | 2020 |
Trafficking through the blood–brain barrier is directed by core and outer surface components of layer‐by‐layer nanoparticles NG Lamson, AJ Pickering, J Wyckoff, P Ganesh, EA Calle, JP Straehla, ... Bioengineering & Translational Medicine 9 (4), e10636, 2024 | 2 | 2024 |
Compositions and Methods for Modulating Permeability of Biological Barriers KA Whitehead, NG Lamson US Patent App. 17/047,772, 2021 | 2 | 2021 |
Correction to “Layer-by-Layer Polymer Functionalization Improves Nanoparticle Penetration and Glioblastoma Targeting in the Brain” AJ Pickering, NG Lamson, MH Marand, W Huang, JP Straehla, ... ACS nano 18 (11), 8555-8555, 2024 | | 2024 |
Comparing Uptake and Transport of Nanomaterials in Preclinical Blood Brain Barrier (BBB) Models Using a Layer-By-Layer Electrostatically Assembled Nanoparticle Library N Lamson, A Pickering, J Wyckoff, P Ganesh, J Straehla, P Hammond 2022 AIChE Annual Meeting, 2022 | | 2022 |
Bending the Drug Delivery Paradigm By Targeting Nanocarriers for Accumulation within the Body’s Intrinsic Barriers N Lamson 2022 AIChE Annual Meeting, 2022 | | 2022 |