Identification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5-HT2A· mGlu2) receptor heteromerization and its psychoactive behavioral function JL Moreno, C Muguruza, A Umali, S Mortillo, T Holloway, F Pilar-Cuéllar, ... Journal of biological chemistry 287 (53), 44301-44319, 2012 | 137 | 2012 |
Dysregulated 5-HT2A receptor binding in postmortem frontal cortex of schizophrenic subjects C Muguruza, JL Moreno, A Umali, LF Callado, JJ Meana, ... European neuropsychopharmacology 23 (8), 852-864, 2013 | 94 | 2013 |
Antipsychotic-induced Hdac2 transcription via NF-κB leads to synaptic and cognitive side effects D Ibi, M de la Fuente Revenga, N Kezunovic, C Muguruza, JM Saunders, ... Nature neuroscience 20 (9), 1247-1259, 2017 | 91 | 2017 |
The endocannabinoid system in mental disorders: Evidence from human brain studies I Ibarra-Lecue, F Pilar-Cuéllar, C Muguruza, E Florensa-Zanuy, Á Díaz, ... Biochemical pharmacology 157, 97-107, 2018 | 88 | 2018 |
Quantification of endocannabinoids in postmortem brain of schizophrenic subjects C Muguruza, M Lehtonen, N Aaltonen, B Morentin, JJ Meana, LF Callado Schizophrenia Research 148 (1-3), 145-150, 2013 | 82 | 2013 |
Evaluation of 5-HT2A and mGlu2/3 receptors in postmortem prefrontal cortex of subjects with major depressive disorder: effect of antidepressant treatment C Muguruza, P Miranda-Azpiazu, R Díez-Alarcia, B Morentin, ... Neuropharmacology 86, 311-318, 2014 | 78 | 2014 |
Group II metabotropic glutamate receptors as targets for novel antipsychotic drugs C Muguruza, JJ Meana, LF Callado Frontiers in pharmacology 7, 130, 2016 | 71 | 2016 |
Long-term hippocampal interneuronopathy drives sex-dimorphic spatial memory impairment induced by prenatal THC exposure A de Salas-Quiroga, D García-Rincón, D Gómez-Domínguez, M Valero, ... Neuropsychopharmacology 45 (5), 877-886, 2020 | 59 | 2020 |
Serotonin 5-HT2A receptor expression and functionality in postmortem frontal cortex of subjects with schizophrenia: Selective biased agonism via Gαi1-proteins A García-Bea, P Miranda-Azpiazu, C Muguruza, ... European Neuropsychopharmacology 29 (12), 1453-1463, 2019 | 42 | 2019 |
Subcellular specificity of cannabinoid effects in striatonigral circuits E Soria-Gomez, ACP Zottola, Y Mariani, T Desprez, M Barresi, ... Neuron 109 (9), 1513-1526. e11, 2021 | 38 | 2021 |
Thiophene/thiazole-benzene replacement on guanidine derivatives targeting α2-Adrenoceptors A Flood, C Trujillo, G Sanchez-Sanz, B Kelly, C Muguruza, LF Callado, ... European journal of medicinal chemistry 138, 38-50, 2017 | 36 | 2017 |
α2-Adrenoceptor Antagonists: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of Pyridinoguanidine, Pyridino-2-aminoimidazoline … B Kelly, M McMullan, C Muguruza, JE Ortega, JJ Meana, LF Callado, ... Journal of Medicinal Chemistry 58 (2), 963-977, 2015 | 34 | 2015 |
Endocannabinoid system imbalance in the postmortem prefrontal cortex of subjects with schizophrenia C Muguruza, B Morentin, JJ Meana, SPH Alexander, LF Callado Journal of Psychopharmacology 33 (9), 1132-1140, 2019 | 32 | 2019 |
The motivation for exercise over palatable food is dictated by cannabinoid type-1 receptors C Muguruza, B Redon, GR Fois, I Hurel, A Scocard, C Nguyen, C Stevens, ... JCI insight 4 (5), 2019 | 32 | 2019 |
Antidepressant-like properties of three new α2-adrenoceptor antagonists C Muguruza, F Rodríguez, I Rozas, JJ Meana, L Urigüen, LF Callado Neuropharmacology 65, 13-19, 2013 | 30 | 2013 |
Bicyclic α-Iminophosphonates as High Affinity Imidazoline I2 Receptor Ligands for Alzheimer’s Disease S Abás, S Rodriguez-Arevalo, A Bagán, C Grinan-Ferre, F Vasilopoulou, ... Journal of medicinal chemistry 63 (7), 3610-3633, 2020 | 24 | 2020 |
Opposite alterations of 5HT2A receptor brain density in subjects with schizophrenia: relevance of radiotracers pharmacological profile R Diez-Alarcia, C Muguruza, G Rivero, A García-Bea, V Gómez-Vallejo, ... Translational Psychiatry 11 (1), 302, 2021 | 18 | 2021 |
Identification of three residues essential for 5-HT2A-mGlu2 receptor heteromerization and its psychoactive behavioral function JL Moreno, C Muguruza, A Umali, S Mortillo, T Holloway, F Pilar-Cuellar, ... J Biol Chem 287 (53), 44301-44319, 2012 | 16 | 2012 |
Differential brain ADRA2A and ADRA2C gene expression and epigenetic regulation in schizophrenia. Effect of antipsychotic drug treatment I Brocos-Mosquera, P Miranda-Azpiazu, C Muguruza, V Corzo-Monje, ... Translational Psychiatry 11 (1), 643, 2021 | 15 | 2021 |
Guanidine-based α2-adrenoceptor ligands: Towards selective antagonist activity DH O'Donovan, C Muguruza, LF Callado, I Rozas European Journal of Medicinal Chemistry 82, 242-254, 2014 | 12 | 2014 |