| A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues D Saul, RL Kosinsky, EJ Atkinson, ML Doolittle, X Zhang, NK LeBrasseur, ... Nature communications 13 (1), 4827, 2022 | 290 | 2022 |
| Targeting the gut microbiome to treat the osteoarthritis of obesity EM Schott, CW Farnsworth, A Grier, JA Lillis, S Soniwala, GH Dadourian, ... JCI insight 3 (8), 2018 | 242 | 2018 |
| Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner A Lagnado, J Leslie, MH Ruchaud‐Sparagano, S Victorelli, P Hirsova, ... The EMBO journal 40 (9), e106048, 2021 | 136 | 2021 |
| Targeted clearance of p21‐ but not p16‐positive senescent cells prevents radiation‐induced osteoporosis and increased marrow adiposity A Chandra, AB Lagnado, JN Farr, M Doolittle, T Tchkonia, JL Kirkland, ... Aging Cell 21 (5), e13602, 2022 | 59 | 2022 |
| Modulation of fracture healing by the transient accumulation of senescent cells D Saul, DG Monroe, JL Rowsey, RL Kosinsky, SJ Vos, ML Doolittle, ... Elife 10, e69958, 2021 | 48 | 2021 |
| Local senolysis in aged mice only partially replicates the benefits of systemic senolysis JN Farr, D Saul, ML Doolittle, J Kaur, JL Rowsey, SJ Vos, MN Froemming, ... The Journal of clinical investigation 133 (8), 2023 | 30 | 2023 |
| The role of senolytics in osteoporosis and other skeletal pathologies ML Doolittle, DG Monroe, JN Farr, S Khosla Mechanisms of ageing and development 199, 111565, 2021 | 26 | 2021 |
| Osteocyte cellular senescence JN Farr, J Kaur, ML Doolittle, S Khosla Current osteoporosis reports 18, 559-567, 2020 | 26 | 2020 |
| Multiparametric senescent cell phenotyping reveals targets of senolytic therapy in the aged murine skeleton ML Doolittle, D Saul, J Kaur, JL Rowsey, SJ Vos, KD Pavelko, JN Farr, ... Nature communications 14 (1), 4587, 2023 | 21 | 2023 |
| Genetic analysis of osteoblast activity identifies Zbtb40 as a regulator of osteoblast activity and bone mass ML Doolittle, GM Calabrese, LD Mesner, DA Godfrey, RD Maynard, ... PLoS genetics 16 (6), e1008805, 2020 | 19 | 2020 |
| A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues. Nat Commun 13: 4827 D Saul, RL Kosinsky, EJ Atkinson, ML Doolittle, X Zhang, NK LeB-rasseur, ... | 18 | 2022 |
| In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers P Samakkarnthai, D Saul, L Zhang, Z Aversa, ML Doolittle, JG Sfeir, ... Aging (Albany NY) 15 (9), 3331, 2023 | 16 | 2023 |
| Identification of a suitable endogenous control miRNA in bone aging and senescence J Kaur, D Saul, ML Doolittle, JL Rowsey, SJ Vos, JN Farr, S Khosla, ... Gene 835, 146642, 2022 | 15 | 2022 |
| SenNet recommendations for detecting senescent cells in different tissues V Suryadevara, AD Hudgins, A Rajesh, A Pappalardo, A Karpova, AK Dey, ... Nature Reviews Molecular Cell Biology, 1-23, 2024 | 13 | 2024 |
| A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues. Nat Commun. 2022; 13: 4827 D Saul, RL Kosinsky, EJ Atkinson, ML Doolittle, X Zhang, NK LeBrasseur, ... | 13 | |
| Isolation and culture of neonatal mouse calvarial osteoblasts ML Doolittle, CL Ackert-Bicknell, JH Jonason Skeletal Development and Repair: Methods and Protocols, 425-436, 2021 | 12 | 2021 |
| Skeletal effects of inducible ERα deletion in osteocytes in adult mice ML Doolittle, D Saul, J Kaur, JL Rowsey, B Eckhardt, S Vos, S Grain, ... Journal of Bone and Mineral Research 37 (9), 1750-1760, 2020 | 10 | 2020 |
| A nondestructive, reproducible method of measuring joint reaction force at the distal radioulnar joint CD Canham, MJ Schreck, N Maqsoodi, M Doolittle, M Olles, JC Elfar The Journal of hand surgery 40 (6), 1138-1144, 2015 | 6 | 2015 |
| Distinct secretomes in p16-and p21-positive senescent cells across tissues D Saul, D Jurk, ML Doolittle, RL Kosinsky, DG Monroe, NK LeBrasseur, ... bioRxiv, 2023 | 5 | 2023 |
| MicroRNA 19a 3p Decreases with Age in Mice and Humans and Inhibits Osteoblast Senescence J Kaur, D Saul, ML Doolittle, JN Farr, S Khosla, DG Monroe Journal of Bone and Mineral Research Plus 7 (6), e10745, 2023 | 5 | 2023 |