The p110δ structure: mechanisms for selectivity and potency of new PI (3) K inhibitors A Berndt, S Miller, O Williams, DD Le, BT Houseman, JI Pacold, F Gorrec, ... Nature chemical biology 6 (2), 117-124, 2010 | 347 | 2010 |
Structural basis for activation and inhibition of class I phosphoinositide 3-kinases O Vadas, JE Burke, X Zhang, A Berndt, RL Williams Science signaling 4 (195), re2-re2, 2011 | 318 | 2011 |
A novel photoreaction mechanism for the circadian blue light photoreceptor Drosophila cryptochrome A Berndt, T Kottke, H Breitkreuz, R Dvorsky, S Hennig, M Alexander, ... Journal of Biological Chemistry 282 (17), 13011-13021, 2007 | 241 | 2007 |
Structures of Drosophila cryptochrome and mouse cryptochrome1 provide insight into circadian function A Czarna, A Berndt, HR Singh, A Grudziecki, AG Ladurner, G Timinszky, ... Cell 153 (6), 1394-1405, 2013 | 215 | 2013 |
Human and Drosophila Cryptochromes Are Light Activated by Flavin Photoreduction in Living Cells N Hoang, E Schleicher, S Kacprzak, JP Bouly, M Picot, W Wu, A Berndt, ... PLoS biology 6 (7), e160, 2008 | 209 | 2008 |
Crystal structure and interactions of the PAS repeat region of the Drosophila clock protein PERIOD Ö Yildiz, M Doi, I Yujnovsky, L Cardone, A Berndt, S Hennig, S Schulze, ... Molecular cell 17 (1), 69-82, 2005 | 134 | 2005 |
Regulation of lipid binding underlies the activation mechanism of class IA PI3-kinases WC Hon, A Berndt, RL Williams Oncogene 31 (32), 3655-3666, 2012 | 126 | 2012 |
Dynamics of the phosphoinositide 3-kinase p110δ interaction with p85α and membranes reveals aspects of regulation distinct from p110α JE Burke, O Vadas, A Berndt, T Finegan, O Perisic, RL Williams Structure 19 (8), 1127-1137, 2011 | 118 | 2011 |
Architecture of human Rag GTPase heterodimers and their complex with mTORC1 M Anandapadamanaban, GR Masson, O Perisic, A Berndt, J Kaufman, ... Science 366 (6462), 203-210, 2019 | 106 | 2019 |
Form and flexibility in phosphoinositide 3-kinases R Williams, A Berndt, S Miller, WC Hon, X Zhang Biochemical Society Transactions 37 (4), 615-626, 2009 | 103 | 2009 |
Tor forms a dimer through an N-terminal helical solenoid with a complex topology D Baretić, A Berndt, Y Ohashi, CM Johnson, RL Williams Nature communications 7 (1), 11016, 2016 | 97 | 2016 |
Measurement of Gamma Knife® helmet factors using MOSFETs L Kurjewicz, A Berndt Medical physics 34 (3), 1007-1012, 2007 | 25 | 2007 |
Identification of a potent phosphoinositide 3‐kinase pan inhibitor displaying a strategic carboxylic acid group and development of its prodrugs T Pirali, E Ciraolo, S Aprile, A Massarotti, A Berndt, A Griglio, M Serafini, ... ChemMedChem 12 (18), 1542-1554, 2017 | 23 | 2017 |
Field-dependent ac susceptibility of amorphous (: Weakly frustrated regime AG Berndt, X Chen, HP Kunkel, G Williams Physical Review B 52 (14), 10160, 1995 | 20 | 1995 |
An algorithm for independent verification of Gamma Knife™ treatment plans J Beck, A Berndt Medical physics 31 (10), 2780-2784, 2004 | 14 | 2004 |
Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace M Heimhalt, A Berndt, J Wagstaff, M Anandapadamanaban, O Perisic, ... Elife 10, e68799, 2021 | 12 | 2021 |
COMP report: CPQR technical quality control guidelines for Gamma Knife radiosurgery A Berndt, M van Prooijen, M Guillot Journal of Applied Clinical Medical Physics 19 (5), 365-367, 2018 | 7 | 2018 |
Effect of skull shape approximations in Gamma Knife dose calculations A Berndt, J Beck Journal of Applied Clinical Medical Physics 8 (3), 52-59, 2007 | 7 | 2007 |
Field-dependent ac susceptibility of amorphous: the strongly frustrated regime AG Berndt, HP Kunkel, G Williams Journal of Physics: Condensed Matter 10 (38), 8535, 1998 | 7 | 1998 |
Size and positioning reproducibility of an brachytherapy stepping source A Berndt, DW Rickey, S Rathee, J Bews Medical Physics 27 (1), 129-131, 2000 | 5 | 2000 |