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Lukáš Opálka
Lukáš Opálka
Assistant professor, Charles University
Verified email at faf.cuni.cz
Title
Cited by
Cited by
Year
Phytosphingosine, sphingosine and dihydrosphingosine ceramides in model skin lipid membranes: permeability and biophysics
B Školová, A Kováčik, O Tesař, L Opálka, K Vávrová
Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (5), 824-834, 2017
832017
Ceramides in the skin barrier
K Vávrová, A Kováčik, L Opálka
European Pharmaceutical Journal 64 (2), 28-35, 2017
832017
Stimulation of PPARα normalizes the skin lipid ratio and improves the skin barrier of normal and filaggrin deficient reconstructed skin
L Wallmeyer, D Lehnen, N Eger, M Sochorová, L Opálka, A Kováčik, ...
Journal of Dermatological Science 80 (2), 102-110, 2015
602015
PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin …
M Pichery, A Huchenq, R Sandhoff, M Severino-Freire, S Zaafouri, ...
Human Molecular Genetics 26 (10), 1787-1800, 2017
562017
Omega-O-Acylceramides in Skin Lipid Membranes: Effects of Concentration, Sphingoid Base, and Model Complexity on Microstructure and Permeability
L Opálka, A Kováčik, J Maixner, K Vávrová
Langmuir 32 (48), 12894-12904, 2016
522016
Scalable synthesis of human ultralong chain ceramides
L Opalka, A Kovacik, M Sochorová, J Roh, J Kunes, J Lenco, K Vávrová
Organic Letters 17 (21), 5456-5459, 2015
522015
Permeability and microstructure of cholesterol-depleted skin lipid membranes and human stratum corneum
M Sochorová, P Audrlická, M Červená, A Kováčik, M Kopečná, L Opálka, ...
Journal of colloid and interface science 535, 227-238, 2019
432019
HILIC/ESI-MS determination of gangliosides and other polar lipid classes in renal cell carcinoma and surrounding normal tissues
R Hájek, M Lísa, M Khalikova, R Jirásko, E Cífková, V Študent, D Vrána, ...
Analytical and bioanalytical chemistry 410, 6585-6594, 2018
422018
Effects of omega-O-acylceramide structures and concentrations in healthy and diseased skin barrier lipid membrane models [S]
L Opálka, A Kováčik, P Pullmannová, J Maixner, K Vávrová
Journal of lipid research 61 (2), 219-228, 2020
362020
Bacterial immunogenic α-galactosylceramide identified in the murine large intestine: dependency on diet and inflammation
J von Gerichten, D Lamprecht, L Opálka, D Soulard, C Marsching, R Pilz, ...
Journal of lipid research 60 (11), 1892-1904, 2019
362019
Synthesis of 6-hydroxyceramide using ruthenium-catalyzed hydrosilylation–protodesilylation. Unexpected formation of a long periodicity lamellar phase in skin lipid membranes
A Kováčik, L Opálka, M Šilarová, J Roh, K Vávrová
RSC advances 6 (77), 73343-73350, 2016
342016
The sphingosine and acyl chains of ceramide [NS] show very different structure and dynamics that challenge our understanding of the skin barrier
O Engberg, A Kováčik, P Pullmannová, M Juhaščik, L Opálka, D Huster, ...
Angewandte Chemie International Edition 59 (40), 17383-17387, 2020
332020
Long and very long lamellar phases in model stratum corneum lipid membranes
P Pullmannová, E Ermakova, A Kováčik, L Opálka, J Maixner, J Zbytovská, ...
Journal of lipid research 60 (5), 963-971, 2019
312019
Non-ionic surfactants as innovative skin penetration enhancers: Insight in the mechanism of interaction with simple 2D stratum corneum model system
F Strati, RHH Neubert, L Opálka, A Kerth, G Brezesinski
European Journal of Pharmaceutical Sciences 157, 105620, 2021
302021
Cellular and metabolic basis for the ichthyotic phenotype in NIPAL4 (Ichthyin)–deficient canines
EA Mauldin, D Crumrine, ML Casal, S Jeong, L Opálka, K Vavrova, ...
The American Journal of Pathology 188 (6), 1419-1429, 2018
262018
Effects of (R)- and (S)-α-Hydroxylation of Acyl Chains in Sphingosine, Dihydrosphingosine, and Phytosphingosine Ceramides on Phase Behavior and …
A Kováčik, P Pullmannová, L Opálka, M Šilarová, J Maixner, K Vávrová
International Journal of Molecular Sciences 22 (14), 7468, 2021
172021
Formation of keto-type ceramides in palmoplantar keratoderma based on biallelic KDSR mutations in patients
R Pilz, L Opálka, A Majcher, E Grimm, L Van Maldergem, S Mihalceanu, ...
Human Molecular Genetics 31 (7), 1105-1114, 2022
162022
Cholesterol sulfate fluidizes the sterol fraction of the stratum corneum lipid phase and increases its permeability
F Fandrei, O Engberg, L Opálka, P Jančálková, P Pullmannová, ...
Journal of Lipid Research 63 (3), 2022
142022
ω-O-Acylceramides but not ω-hydroxy ceramides are required for healthy lamellar phase architecture of skin barrier lipids
L Opálka, JM Meyer, V Ondrejčeková, L Svatošová, FPW Radner, ...
Journal of Lipid Research 63 (6), 2022
122022
The intriguing molecular dynamics of Cer [EOS] in rigid skin barrier lipid layers requires improvement of the model
F Fandrei, T Havrišák, L Opálka, O Engberg, AA Smith, P Pullmannová, ...
Journal of Lipid Research 64 (5), 2023
92023
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