Succinate is an inflammatory signal that induces IL-1β through HIF-1α GM Tannahill, AM Curtis, J Adamik, EM Palsson-McDermott, ... Nature 496 (7444), 238-242, 2013 | 3621 | 2013 |
Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4 A Asea, M Rehli, E Kabingu, JA Boch, O Baré, PE Auron, MA Stevenson, ... Journal of Biological Chemistry 277 (17), 15028-15034, 2002 | 2041 | 2002 |
Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. PE Auron, AC Webb, LJ Rosenwasser, SF Mucci, A Rich, SM Wolff, ... Proceedings of the National Academy of Sciences 81 (24), 7907-7911, 1984 | 1519 | 1984 |
Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFκB J Yang, X Liao, MK Agarwal, L Barnes, PE Auron, GR Stark Genes & development 21 (11), 1396-1408, 2007 | 715 | 2007 |
Negative cross-talk between hematopoietic regulators: GATA proteins repress PU. 1 P Zhang, G Behre, J Pan, A Iwama, N Wara-Aswapati, HS Radomska, ... Proceedings of the National Academy of Sciences 96 (15), 8705-8710, 1999 | 600 | 1999 |
Multiple biological activities of human recombinant interleukin 1. CA Dinarello, JG Cannon, JW Mier, HA Bernheim, G LoPreste, DL Lynn, ... The Journal of clinical investigation 77 (6), 1734-1739, 1986 | 495 | 1986 |
The CCAAT/enhancer (C/EBP) family of basic-leucine zipper (bZIP) transcription factors is a multifaceted highly-regulated system for gene regulation J Tsukada, Y Yoshida, Y Kominato, PE Auron Cytokine 54 (1), 6-19, 2011 | 366 | 2011 |
Translational control during the acute phase response. Ferritin synthesis in response to interleukin-1. JT Rogers, KR Bridges, GP Durmowicz, J Glass, PE Auron, HN Munro Journal of Biological Chemistry 265 (24), 14572-14578, 1990 | 323 | 1990 |
The interleukin 1 receptor: ligand interactions and signal transduction PE Auron Cytokine & growth factor reviews 9 (3-4), 221-237, 1998 | 267 | 1998 |
Genomic sequence for human prointerleukin 1 beta: possible evolution from a reverse transcribed prointerleukin 1 alpha gene BD Clark, KL Collins, MS Gandy, AC Webb, PE Auron Nucleic acids research 14 (20), 7897-7914, 1986 | 263 | 1986 |
Human pro-IL-1 beta gene expression in monocytic cells is regulated by two distinct pathways. MJ Fenton, MW Vermeulen, BD Clark, AC Webb, PE Auron Journal of immunology (Baltimore, Md.: 1950) 140 (7), 2267-2273, 1988 | 256 | 1988 |
Transcriptional repression of the prointerleukin 1β gene by heat shock factor 1 CM Cahill, WR Waterman, Y Xie, PE Auron, SK Calderwood Journal of Biological Chemistry 271 (40), 24874-24879, 1996 | 248 | 1996 |
Studies on the molecular nature of human interleukin 1. PE Auron, SJ Warner, AC Webb, JG Cannon, HA Bernheim, KJ McAdam, ... Journal of immunology (Baltimore, Md.: 1950) 138 (5), 1447-1456, 1987 | 240 | 1987 |
Cloning, characterization, and expression of a human calcitonin receptor from an ovarian carcinoma cell line. AH Gorn, HY Lin, M Yamin, PE Auron, MR Flannery, DR Tapp, ... The Journal of clinical investigation 90 (5), 1726-1735, 1992 | 236 | 1992 |
The human prointerleukin 1β gene requires DNA sequences both proximal and distal to the transcription start site for tissue-specific induction F Shirakawa, K Saito, CA Bonagura, DL Galson, MJ Fenton, AC Webb, ... Molecular and cellular biology 13 (3), 1332-1344, 1993 | 216 | 1993 |
Heat shock factor 1 represses transcription of the IL-1β gene through physical interaction with the nuclear factor of interleukin 6 Y Xie, C Chen, MA Stevenson, PE Auron, SK Calderwood Journal of Biological Chemistry 277 (14), 11802-11810, 2002 | 212 | 2002 |
Transcriptional regulation of the human prointerleukin 1 beta gene. MJ Fenton, BD Clark, KL Collins, AC Webb, A Rich, PE Auron Journal of immunology (Baltimore, Md.: 1950) 138 (11), 3972-3979, 1987 | 211 | 1987 |
Transcription factors NF-IL6 and CREB recognize a common essential site in the human prointerleukin 1β gene J Tsukada, K Saito, WR Waterman, AC Webb, PE Auron Molecular and cellular biology, 1994 | 203 | 1994 |
Interleukin-1 gene (IL1) assigned to long arm of human chromosome 2. AC Webb, KL Collins, PE Auron, RL Eddy, H Nakai, MG Byers, LL Haley, ... Lymphokine research 5 (2), 77-85, 1986 | 193 | 1986 |
Monocyte expression of the human prointerleukin 1β gene (IL1B) is dependent on promoter sequences which bind the hematopoietic transcription factor Spi-1/PU. 1 Y Kominato, DL Galson, WR Waterman, AC Webb, PE Auron Molecular and cellular biology, 1995 | 190 | 1995 |