Electron capture dissociation of multiply charged protein cations. A nonergodic process RA Zubarev, NL Kelleher, FW McLafferty Journal of the American Chemical Society 120 (13), 3265-3266, 1998 | 2400 | 1998 |
Proteoform: a single term describing protein complexity LM Smith, NL Kelleher Nature methods 10 (3), 186-187, 2013 | 1532 | 2013 |
Electron capture dissociation for structural characterization of multiply charged protein cations RA Zubarev, DM Horn, EK Fridriksson, NL Kelleher, NA Kruger, MA Lewis, ... Analytical chemistry 72 (3), 563-573, 2000 | 1216 | 2000 |
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation W Béguelin, R Popovic, M Teater, Y Jiang, KL Bunting, M Rosen, H Shen, ... Cancer cell 23 (5), 677-692, 2013 | 931 | 2013 |
How many human proteoforms are there? R Aebersold, JN Agar, IJ Amster, MS Baker, CR Bertozzi, ES Boja, ... Nature chemical biology 14 (3), 206-214, 2018 | 841 | 2018 |
Mapping intact protein isoforms in discovery mode using top-down proteomics JC Tran, L Zamdborg, DR Ahlf, JE Lee, AD Catherman, KR Durbin, ... Nature 480 (7376), 254-258, 2011 | 768 | 2011 |
Top down versus bottom up protein characterization by tandem high-resolution mass spectrometry NL Kelleher, HY Lin, GA Valaskovic, DJ Aaserud, EK Fridriksson, ... Journal of the American Chemical Society 121 (4), 806-812, 1999 | 749 | 1999 |
Peer reviewed: top-down proteomics NL Kelleher Analytical chemistry 76 (11), 196 A-203 A, 2004 | 727 | 2004 |
Top down proteomics: facts and perspectives AD Catherman, OS Skinner, NL Kelleher Biochemical and biophysical research communications 445 (4), 683-693, 2014 | 648 | 2014 |
A computational framework to explore large-scale biosynthetic diversity JC Navarro-Muñoz, N Selem-Mojica, MW Mullowney, SA Kautsar, ... Nature chemical biology 16 (1), 60-68, 2020 | 619 | 2020 |
Progress in top-down proteomics and the analysis of proteoforms TK Toby, L Fornelli, NL Kelleher Annual review of analytical chemistry 9 (1), 499-519, 2016 | 619 | 2016 |
Decoding protein modifications using top-down mass spectrometry N Siuti, NL Kelleher Nature methods 4 (10), 817-821, 2007 | 588 | 2007 |
A roadmap for natural product discovery based on large-scale genomics and metabolomics JR Doroghazi, JC Albright, AW Goering, KS Ju, RR Haines, KA Tchalukov, ... Nature chemical biology 10 (11), 963-968, 2014 | 522 | 2014 |
Precision proteomics: the case for high resolution and high mass accuracy M Mann, NL Kelleher Proceedings of the National Academy of Sciences 105 (47), 18132-18138, 2008 | 506 | 2008 |
Genetically encoded short peptide tag for versatile protein labeling by Sfp phosphopantetheinyl transferase J Yin, PD Straight, SM McLoughlin, Z Zhou, AJ Lin, DE Golan, NL Kelleher, ... Proceedings of the National Academy of Sciences 102 (44), 15815-15820, 2005 | 488 | 2005 |
Attomole protein characterization by capillary electrophoresis-mass spectrometry GA Valaskovic, NL Kelleher, FW McLafferty Science 273 (5279), 1199-1202, 1996 | 478 | 1996 |
Localization of labile posttranslational modifications by electron capture dissociation: the case of γ-carboxyglutamic acid NL Kelleher, RA Zubarev, K Bush, B Furie, BC Furie, FW McLafferty, ... Analytical chemistry 71 (19), 4250-4253, 1999 | 451 | 1999 |
A monovalent streptavidin with a single femtomolar biotin binding site M Howarth, DJF Chinnapen, K Gerrow, PC Dorrestein, MR Grandy, ... Nature methods 3 (4), 267-273, 2006 | 450 | 2006 |
The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t (4; 14) multiple myeloma cells E Martinez-Garcia, R Popovic, DJ Min, SMM Sweet, PM Thomas, ... Blood, The Journal of the American Society of Hematology 117 (1), 211-220, 2011 | 420 | 2011 |
Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation JB Shaw, W Li, DD Holden, Y Zhang, J Griep-Raming, RT Fellers, ... Journal of the American Chemical Society 135 (34), 12646-12651, 2013 | 402 | 2013 |