| Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, FC Abdalla, H Abeliovich, RT Abraham, A Acevedo-Arozena, ... Autophagy 8 (4), 445-544, 2012 | 13192* | 2012 |
| 1‐Benzyl‐1, 2, 3, 4‐tetrahydroisoquinoline as a parkinsonism‐inducing agent: a novel endogenous amine in mouse brain and parkinsonian CSF Y Kotake, Y Tasaki, Y Makino, S Ohta, M Hirobe Journal of neurochemistry 65 (6), 2633-2638, 1995 | 197 | 1995 |
| Molecular mechanisms of environmental organotin toxicity in mammals Y Kotake Biological and Pharmaceutical Bulletin 35 (11), 1876-1880, 2012 | 84 | 2012 |
| Chronic administration of 1-benzyl-1, 2, 3, 4-tetrahydroisoquinoline, an endogenous amine in the brain, induces parkinsonism in a primate Y Kotake, M Yoshida, M Ogawa, Y Tasaki, M Hirobe, S Ohta Neuroscience letters 217 (1), 69-71, 1996 | 83 | 1996 |
| Concentration dependence of the mechanisms of tributyltin-induced apoptosis Y Nakatsu, Y Kotake, S Ohta Toxicological sciences 97 (2), 438-447, 2007 | 82 | 2007 |
| Prediction of in vivo hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver S Sanoh, A Horiguchi, K Sugihara, Y Kotake, Y Tayama, H Ohshita, ... Drug Metabolism and Disposition 40 (2), 322-328, 2012 | 80 | 2012 |
| Glutamate excitotoxicity is involved in cell death caused by tributyltin in cultured rat cortical neurons Y Nakatsu, Y Kotake, K Komasaka, H Hakozaki, R Taguchi, T Kume, ... Toxicological Sciences 89 (1), 235-242, 2006 | 80 | 2006 |
| Modulation of connexin 43 in rotenone-induced model of Parkinson's disease A Kawasaki, T Hayashi, K Nakachi, JE Trosko, K Sugihara, Y Kotake, ... Neuroscience 160 (1), 61-68, 2009 | 76 | 2009 |
| Annonamine, a new aporphine alkaloid from the leaves of Annona muricata A Matsushige, Y Kotake, K Matsunami, H Otsuka, S Ohta, Y Takeda Chemical and Pharmaceutical Bulletin 60 (2), 257-259, 2012 | 74 | 2012 |
| MPP+ analogs acting on mitochondria and inducing neuro-degeneration Y Kotake, S Ohta Current medicinal chemistry 10 (23), 2507-2516, 2003 | 67 | 2003 |
| Activation of AMP-activated protein kinase by tributyltin induces neuronal cell death Y Nakatsu, Y Kotake, A Hino, S Ohta Toxicology and applied pharmacology 230 (3), 358-363, 2008 | 65 | 2008 |
| Effects of various tetrahydroisoquinoline derivatives on mitochondrial respiration and the electron transfer complexes N Morikawa, M Naoi, W Maruyama, S Ohta, Y Kotake, H Kawai, T Niwa, ... Journal of neural transmission 105, 677-688, 1998 | 65 | 1998 |
| Regional distribution of parkinsonism-preventing endogenous tetrahydroisoquinoline derivatives and an endogenous parkinsonism-preventing substance-synthesizing enzyme in monkey … T Yamakawa, Y Kotake, M Fujitani, H Shintani, Y Makino, S Ohta Neuroscience letters 276 (1), 68-70, 1999 | 63 | 1999 |
| Protein disulfide isomerase knockdown-induced cell death is cell-line-dependent and involves apoptosis in MCF-7 cells T Hashida, Y Kotake, S Ohta The Journal of toxicological sciences 36 (1), 1-7, 2011 | 58 | 2011 |
| Predictability of plasma concentration–time curves in humans using single-species allometric scaling of chimeric mice with humanized liver S Sanoh, Y Naritomi, M Fujimoto, K Sato, A Kawamura, A Horiguchi, ... Xenobiotica 45 (7), 605-614, 2015 | 48 | 2015 |
| Predictability of metabolism of ibuprofen and naproxen using chimeric mice with human hepatocytes S Sanoh, A Horiguchi, K Sugihara, Y Kotake, Y Tayama, N Uramaru, ... Drug Metabolism and Disposition 40 (12), 2267-2272, 2012 | 46 | 2012 |
| Three new megastigmanes from the leaves of Annona muricata A Matsushige, K Matsunami, Y Kotake, H Otsuka, S Ohta Journal of natural medicines 66, 284-291, 2012 | 45 | 2012 |
| Tributyltin-induced endoplasmic reticulum stress and its Ca2+-mediated mechanism M Isomura, Y Kotake, K Masuda, M Miyara, K Okuda, S Samizo, S Sanoh, ... Toxicology and applied pharmacology 272 (1), 137-146, 2013 | 43 | 2013 |
| Involvement of autophagy via mammalian target of rapamycin (mTOR) inhibition in tributyltin-induced neuronal cell death Y Nakatsu, Y Kotake, N Takai, S Ohta The Journal of toxicological sciences 35 (2), 245-251, 2010 | 42 | 2010 |
| Detection and determination of reticuline and N-methylcoculaurine in the Annonaceae family using liquid chromatography-tandem mass spectrometry Y Kotake, K Okuda, M Kamizono, N Matsumoto, T Tanahashi, H Hara, ... Journal of Chromatography B 806 (1), 75-78, 2004 | 41 | 2004 |
