| BMP4 signaling acts via dual-specificity phosphatase 9 to control ERK activity in mouse embryonic stem cells Z Li, T Fei, J Zhang, G Zhu, L Wang, D Lu, X Chi, Y Teng, N Hou, X Yang, ... Cell stem cell 10 (2), 171-182, 2012 | 190 | 2012 |
| A human three-dimensional neural-perivascular ‘assembloid’promotes astrocytic development and enables modeling of SARS-CoV-2 neuropathology L Wang, D Sievert, AE Clark, S Lee, H Federman, BD Gastfriend, ... Nature medicine 27 (9), 1600-1606, 2021 | 112 | 2021 |
| Signaling control of differentiation of embryonic stem cells toward mesendoderm L Wang, YG Chen Journal of molecular biology 428 (7), 1409-1422, 2016 | 66 | 2016 |
| Loss of NARS1 impairs progenitor proliferation in cortical brain organoids and leads to microcephaly L Wang, Z Li, D Sievert, DEC Smith, MI Mendes, DY Chen, V Stanley, ... Nature Communications 11 (1), 4038, 2020 | 64 | 2020 |
| De novo and bi-allelic pathogenic variants in NARS1 cause neurodevelopmental delay due to toxic gain-of-function and partial loss-of-function effects A Manole, S Efthymiou, E O’Connor, MI Mendes, M Jennings, ... The American Journal of Human Genetics 107 (2), 311-324, 2020 | 47 | 2020 |
| Loss of the neural-specific BAF subunit ACTL6B relieves repression of early response genes and causes recessive autism W Wenderski, L Wang, A Krokhotin, JJ Walsh, H Li, H Shoji, S Ghosh, ... Proceedings of the National Academy of Sciences 117 (18), 10055-10066, 2020 | 40 | 2020 |
| Activin/Smad2-induced histone H3 Lys-27 trimethylation (H3K27me3) reduction is crucial to initiate mesendoderm differentiation of human embryonic stem cells L Wang, X Xu, Y Cao, Z Li, H Cheng, G Zhu, F Duan, J Na, JDJ Han, ... Journal of Biological Chemistry 292 (4), 1339-1350, 2017 | 34 | 2017 |
| BMP induces cochlin expression to facilitate self-renewal and suppress neural differentiation of mouse embryonic stem cells J Zhang, T Fei, Z Li, G Zhu, L Wang, YG Chen Journal of Biological Chemistry 288 (12), 8053-8060, 2013 | 34 | 2013 |
| A human pleiotropic multiorgan condition caused by deficient Wnt secretion G Chai, E Szenker-Ravi, C Chung, Z Li, L Wang, M Khatoo, T Marshall, ... New England Journal of Medicine 385 (14), 1292-1301, 2021 | 29 | 2021 |
| Stem cell–based organoid models of neurodevelopmental disorders L Wang, C Owusu-Hammond, D Sievert, JG Gleeson Biological psychiatry 93 (7), 622-631, 2023 | 11 | 2023 |
| Activin/Smad2 and Wnt/β-catenin up-regulate HAS2 and ALDH3A2 to facilitate mesendoderm differentiation of human embryonic stem cells X Xu, L Wang, B Liu, W Xie, YG Chen Journal of Biological Chemistry 293 (48), 18444-18453, 2018 | 11 | 2018 |
| Recurrent homozygous damaging mutation in TMX2, encoding a protein disulfide isomerase, in four families with microlissencephaly SG Ghosh, L Wang, MW Breuss, JD Green, V Stanley, X Yang, D Ross, ... Journal of medical genetics 57 (4), 274-282, 2020 | 9 | 2020 |
| Buprenorphine and methadone differentially alter early brain development in human cortical organoids H Yao, D Hu, J Wang, W Wu, HH Zhao, L Wang, J Gleeson, GG Haddad Neuropharmacology 239, 109683, 2023 | 5 | 2023 |
| TMEM161B modulates radial glial scaffolding in neocortical development L Wang, C Heffner, K Vong, C Barrows, YJ Ha, S Lee, P Lara-Gonzalez, ... Proceedings of the National Academy of Sciences 120 (4), e2209983120, 2023 | 5 | 2023 |
| A Human 3D neural assembloid model for SARS-CoV-2 infection L Wang, D Sievert, J Gleeson, AE Clark, AF Carlin, H Federman, ... Research square, 2021 | 4 | 2021 |
| Author Correction: Loss of NARS1 impairs progenitor proliferation in cortical brain organoids and leads to microcephaly L Wang, Z Li, D Sievert, DEC Smith, MI Mendes, DY Chen, V Stanley, ... Nature communications 12 (1), 1192, 2021 | 3 | 2021 |
Joseph G. GleesonUniversity of California, San DiegoVerified email at ucsd.edu