Covalent ligand screening uncovers a RNF4 E3 ligase recruiter for targeted protein degradation applications CC Ward, JI Kleinman, SM Brittain, PS Lee, CYS Chung, K Kim, Y Petri, ... ACS chemical biology 14 (11), 2430-2440, 2019 | 251 | 2019 |
Highly luminescent palladium (II) complexes with sub-millisecond blue to green phosphorescent excited states. Photocatalysis and highly efficient PSF-OLEDs PK Chow, G Cheng, GSM Tong, C Ma, WM Kwok, WH Ang, CYS Chung, ... Chemical Science 7 (9), 6083-6098, 2016 | 168 | 2016 |
Induced self-assembly and Forster resonance energy transfer studies of alkynylplatinum (II) terpyridine complex through interaction with water-soluble poly (phenylene … CYS Chung, VWW Yam Journal of the American Chemical Society 133 (46), 18775-18784, 2011 | 152 | 2011 |
Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition CYS Chung, HR Shin, CA Berdan, B Ford, CC Ward, JA Olzmann, ... Nature chemical biology 15 (8), 776-785, 2019 | 146 | 2019 |
Cyclometalated Palladium (II) N‐Heterocyclic Carbene Complexes: Anticancer Agents for Potent In Vitro Cytotoxicity and In Vivo Tumor Growth Suppression TTH Fong, CN Lok, CYS Chung, YME Fung, PK Chow, PK Wan, CM Che Angewandte Chemie International Edition 55 (39), 11935-11939, 2016 | 126 | 2016 |
Stable luminescent iridium (III) complexes with bis (N-heterocyclic carbene) ligands: photo-stability, excited state properties, visible-light-driven radical cyclization and CO … C Yang, F Mehmood, TL Lam, SLF Chan, Y Wu, CS Yeung, X Guan, K Li, ... Chemical Science 7 (5), 3123-3136, 2016 | 126 | 2016 |
Activity-based ratiometric FRET probe reveals oncogene-driven changes in labile copper pools induced by altered glutathione metabolism CYS Chung, JM Posimo, S Lee, T Tsang, JM Davis, DC Brady, CJ Chang Proceedings of the National Academy of Sciences 116 (37), 18285-18294, 2019 | 112 | 2019 |
Induced self-assembly and disassembly of water-soluble alkynylplatinum (II) terpyridyl complexes with “switchable” near-infrared (NIR) emission modulated by metal–metal … CYS Chung, SPY Li, MW Louie, KKW Lo, VWW Yam Chemical Science 4 (6), 2453-2462, 2013 | 108 | 2013 |
Versatile histochemical approach to detection of hydrogen peroxide in cells and tissues based on puromycin staining C Yik-Sham Chung, GA Timblin, K Saijo, CJ Chang Journal of the American Chemical Society 140 (19), 6109-6121, 2018 | 92 | 2018 |
Metal–metal and π–π interactions directed end-to-end assembly of gold nanorods FCM Leung, SYL Leung, CYS Chung, VWW Yam Journal of the American Chemical Society 138 (9), 2989-2992, 2016 | 71 | 2016 |
“Proof-of-principle” concept for label-free detection of glucose and α-glucosidase activity through the electrostatic assembly of alkynylplatinum (II) terpyridyl complexes CYS Chung, KHY Chan, VWW Yam Chemical communications 47 (7), 2000-2002, 2011 | 71 | 2011 |
Nidogen 1‐enriched extracellular vesicles facilitate extrahepatic metastasis of liver cancer by activating pulmonary fibroblasts to secrete tumor necrosis factor receptor 1 X Mao, SK Tey, CLS Yeung, EML Kwong, YME Fung, CYS Chung, ... Advanced Science 7 (21), 2002157, 2020 | 67 | 2020 |
Activity-based sensing with a metal-directed acyl imidazole strategy reveals cell type-dependent pools of labile brain copper S Lee, CYS Chung, P Liu, L Craciun, Y Nishikawa, KJ Bruemmer, ... Journal of the American Chemical Society 142 (35), 14993-15003, 2020 | 66 | 2020 |
A multi-functional PEGylated gold (iii) compound: potent anti-cancer properties and self-assembly into nanostructures for drug co-delivery CYS Chung, SK Fung, KC Tong, PK Wan, CN Lok, Y Huang, T Chen, ... Chemical Science 8 (3), 1942-1953, 2017 | 60 | 2017 |
Selective label-free detection of G-quadruplex structure of human telomere by emission spectral changes in visible-and-NIR region under physiological condition through the FRET … CYS Chung, VWW Yam Chemical Science 4 (1), 377-387, 2013 | 57 | 2013 |
Ephrin-A3/EphA2 axis regulates cellular metabolic plasticity to enhance cancer stemness in hypoxic hepatocellular carcinoma A Husain, YT Chiu, KMF Sze, DWH Ho, YM Tsui, EMS Suarez, VX Zhang, ... Journal of hepatology 77 (2), 383-396, 2022 | 52 | 2022 |
Dual pH‐and Temperature‐Responsive Metallosupramolecular Block Copolymers with Tunable Critical Micelle Temperature by Modulation of the Self‐Assembly of NIR‐Emissive … CYS Chung, VWW Yam Chemistry–A European Journal 19 (39), 13182-13192, 2013 | 45 | 2013 |
Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer MHR Bao, C Yang, APW Tse, L Wei, D Lee, MS Zhang, CC Goh, ... Cell Reports 34 (4), 2021 | 43 | 2021 |
Reversible pH-and solvent-responsive micelle-mediated self-assembly of platinum (II) terpyridyl-based metallo-supramolecular diblock copolymers VWW Yam, Y Hu, KHY Chan, CYS Chung Chemical Communications, 6216-6218, 2009 | 43 | 2009 |
Reversible thermo-responsive luminescent metallo-supramolecular triblock copolymers based on platinum (II) terpyridyl chromophores with unusual aggregation behaviour and red … Y Hu, KHY Chan, CYS Chung, VWW Yam Dalton Transactions 40 (45), 12228-12234, 2011 | 36 | 2011 |