JAK-STAT signaling in cancer: From cytokines to non-coding genome J Pencik, HTT Pham, J Schmoellerl, T Javaheri, M Schlederer, Z Culig, ... Cytokine 87, 26-36, 2016 | 239 | 2016 |
Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia CD Herling, N Abedpour, J Weiss, A Schmitt, RD Jachimowicz, O Merkel, ... Nature communications 9 (1), 727, 2018 | 210 | 2018 |
p53-dependent non-coding RNA networks in chronic lymphocytic leukemia CJ Blume, A Hotz-Wagenblatt, J Hüllein, L Sellner, A Jethwa, T Stolz, ... Leukemia 29 (10), 2015 | 186 | 2015 |
STAT3 regulated ARF expression suppresses prostate cancer metastasis J Pencik, M Schlederer, W Gruber, C Unger, SM Walker, A Chalaris, ... Nature communications 6 (1), 7736, 2015 | 182 | 2015 |
Mitochondrial phosphate–carrier deficiency: A novel disorder of oxidative phosphorylation JA Mayr, O Merkel, SD Kohlwein, BR Gebhardt, H Böhles, U Fötschl, ... The American Journal of Human Genetics 80 (3), 478-484, 2007 | 178 | 2007 |
Image-based ex-vivo drug screening for patients with aggressive haematological malignancies: interim results from a single-arm, open-label, pilot study B Snijder, GI Vladimer, N Krall, K Miura, AS Schmolke, C Kornauth, ... The Lancet Haematology 4 (12), e595-e606, 2017 | 176 | 2017 |
The role of activator protein-1 (AP-1) family members in CD30-positive lymphomas I Garces de los Fayos Alonso, HC Liang, SD Turner, S Lagger, O Merkel, ... Cancers 10 (4), 93, 2018 | 155 | 2018 |
Characterization and function in vivo of two novel phospholipases B/lysophospholipases fromSaccharomyces cerevisiae O Merkel, M Fido, JA Mayr, H Prüger, F Raab, G Zandonella, ... Journal of Biological Chemistry 274 (40), 28121-28127, 1999 | 149 | 1999 |
PDGFR blockade is a rational and effective therapy for NPM-ALK–driven lymphomas D Laimer, H Dolznig, K Kollmann, PW Vesely, M Schlederer, O Merkel, ... Nature medicine 18 (11), 1699-1704, 2012 | 144 | 2012 |
microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia D Asslaber, JD Piñón, I Seyfried, P Desch, M Stöcher, I Tinhofer, A Egle, ... Blood, The Journal of the American Society of Hematology 115 (21), 4191-4197, 2010 | 144 | 2010 |
Structure and function of the BAH-containing domain of Orc1p in epigenetic silencing Z Zhang, MK Hayashi, O Merkel, B Stillman, RM Xu The EMBO journal 21 (17), 4600-4611, 2002 | 134 | 2002 |
Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+ and ALK− anaplastic large-cell lymphoma O Merkel, F Hamacher, D Laimer, E Sifft, Z Trajanoski, M Scheideler, ... Proceedings of the National Academy of Sciences 107 (37), 16228-16233, 2010 | 129 | 2010 |
Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma A Weilemann, M Grau, T Erdmann, O Merkel, U Sobhiafshar, ... Blood, The Journal of the American Society of Hematology 125 (1), 124-132, 2015 | 105 | 2015 |
Functional precision medicine provides clinical benefit in advanced aggressive hematologic cancers and identifies exceptional responders C Kornauth, T Pemovska, GI Vladimer, G Bayer, M Bergmann, S Eder, ... Cancer discovery 12 (2), 372-387, 2022 | 103 | 2022 |
Anaplastic large cell lymphoma arises in thymocytes and requires transient TCR expression for thymic egress TIM Malcolm, P Villarese, CJ Fairbairn, L Lamant, A Trinquand, CE Hook, ... Nature communications 7 (1), 10087, 2016 | 93 | 2016 |
The AP-1-BATF and-BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma N Schleussner, O Merkel, M Costanza, HC Liang, F Hummel, ... Leukemia 32 (9), 1994-2007, 2018 | 88 | 2018 |
When the guardian sleeps: Reactivation of the p53 pathway in cancer O Merkel, N Taylor, N Prutsch, PB Staber, R Moriggl, SD Turner, L Kenner Mutation Research/Reviews in Mutation Research 773, 1-13, 2017 | 76 | 2017 |
First-in-human response of BCL-2 inhibitor venetoclax in T-cell prolymphocytic leukemia B Boidol, C Kornauth, E van der Kouwe, N Prutsch, L Kazianka, ... Blood, The Journal of the American Society of Hematology 130 (23), 2499-2503, 2017 | 73 | 2017 |
Insights into the pathogenesis of anaplastic large-cell lymphoma through genome-wide DNA methylation profiling MR Hassler, W Pulverer, R Lakshminarasimhan, E Redl, J Hacker, ... Cell reports 17 (2), 596-608, 2016 | 72 | 2016 |
Oncogenic role of miR‐155 in anaplastic large cell lymphoma lacking the t (2; 5) translocation O Merkel, F Hamacher, R Griessl, L Grabner, AI Schiefer, N Prutsch, ... The Journal of pathology 236 (4), 445-456, 2015 | 66 | 2015 |