Functional impairment of lens aquaporin in two families with dominantly inherited cataracts P Francis, JJ Chung, M Yasui, V Berry, A Moore, MK Wyatt, G Wistow, ... Human molecular genetics 9 (15), 2329-2334, 2000 | 182 | 2000 |
The P23T cataract mutation causes loss of solubility of folded γD-crystallin P Evans, K Wyatt, GJ Wistow, OA Bateman, BA Wallace, C Slingsby Journal of molecular biology 343 (2), 435-444, 2004 | 133 | 2004 |
Expressed sequence tag analysis of adult human lens for the NEIBank Project: over 2000 non-redundant transcripts, novel genes and splice variants G Wistow, SL Bernstein, MK Wyatt, A Behal, JW Touchman, G Bouffard, ... Mol Vis 8, 171-184, 2002 | 118 | 2002 |
γN‐crystallin and the evolution of the βγ‐crystallin superfamily in vertebrates G Wistow, K Wyatt, L David, C Gao, O Bateman, S Bernstein, S Tomarev, ... The FEBS journal 272 (9), 2276-2291, 2005 | 104 | 2005 |
Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants G Wistow, SL Bernstein, MK Wyatt, RN Fariss, A Behal, JW Touchman, ... Mol Vis 8 (21), 205-220, 2002 | 92 | 2002 |
Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene … G Wistow, SL Bernstein, MK Wyatt, S Ray, A Behal, JW Touchman, ... Mol Vis 8 (21), 196-204, 2002 | 72 | 2002 |
A temperature-sensitive mutation of Crygs in the murine Opj cataract D Sinha, MK Wyatt, R Sarra, C Jaworski, C Slingsby, C Thaung, L Pannell, ... Journal of Biological Chemistry 276 (12), 9308-9315, 2001 | 69 | 2001 |
Expressed sequence tag analysis of adult human iris for the NEIBank Project: steroid-response factors and similarities with retinal pigment epithelium G Wistow, SL Bernstein, S Ray, MK Wyatt, A Behal, JW Touchman, ... Mol Vis 8 (21), 185-195, 2002 | 60 | 2002 |
Solution structure of γS‐crystallin by molecular fragment replacement NMR Z Wu, F Delaglio, K Wyatt, G Wistow, A Bax Protein science 14 (12), 3101-3114, 2005 | 58 | 2005 |
Cloning, modeling, and chromosomal localization for a small leucine-rich repeat proteoglycan (SLRP) family member expressed in human eye P Hobby, MK Wyatt, W Gan, S Bernstein, S Tomarev, C Slingsby, ... Mol Vis 6, 72-8, 2000 | 55 | 2000 |
Gene duplication and separation of functions in αB‐crystallin from zebrafish (Danio rerio) AA Smith, K Wyatt, J Vacha, TS Vihtelic, J Samuel Zigler Jr, GJ Wistow, ... The FEBS journal 273 (3), 481-490, 2006 | 47 | 2006 |
Interaction of complement factor h and fibulin3 in age-related macular degeneration MK Wyatt, JY Tsai, S Mishra, M Campos, C Jaworski, RN Fariss, ... PloS one 8 (6), e68088, 2013 | 46 | 2013 |
Platelet-derived growth factor D, tissue-specific expression in the eye, and a key role in control of lens epithelial cell proliferation S Ray, C Gao, K Wyatt, RN Fariss, A Bundek, P Zelenka, G Wistow Journal of Biological Chemistry 280 (9), 8494-8502, 2005 | 44 | 2005 |
A single destabilizing mutation (F9S) promotes concerted unfolding of an entire globular domain in γS-crystallin S Lee, B Mahler, J Toward, B Jones, K Wyatt, L Dong, G Wistow, Z Wu Journal of molecular biology 399 (2), 320-330, 2010 | 42 | 2010 |
Lengsin is a survivor of an ancient family of class I glutamine synthetases re-engineered by evolution for a role in the vertebrate lens K Wyatt, HE White, L Wang, OA Bateman, C Slingsby, EV Orlova, ... Structure 14 (12), 1823-1834, 2006 | 42 | 2006 |
Structure-function of cytochromes P450 and flavin-containing monooxygenases: implications for drug metabolism JR Halpert, TL Domanski, O Adali, CP Biagini, J Cosme, EA Dierks, ... Drug metabolism and disposition 26 (12), 1223-1231, 1998 | 31 | 1998 |
A role for lengsin, a recruited enzyme, in terminal differentiation in the vertebrate lens K Wyatt, C Gao, JY Tsai, RN Fariss, S Ray, G Wistow Journal of Biological Chemistry 283 (10), 6607-6615, 2008 | 30 | 2008 |
Biophysical properties of γC-crystallin in human and mouse eye lens: the role of molecular dipoles AG Purkiss, OA Bateman, K Wyatt, PA Wilmarth, LL David, GJ Wistow, ... Journal of molecular biology 372 (1), 205-222, 2007 | 30 | 2007 |
Grouping and identification of sequence tags (GRIST): bioinformatics tools for the NEIBank database G Wistow, SL Bernstein, JW Touchman, G Bouffard, MK Wyatt, K Peterson, ... Mol Vis 8, 164-70, 2002 | 29 | 2002 |
The human gene for gammaS-crystallin: alternative transcripts and expressed sequences from the first intron G Wistow, L Sardarian, W Gan, MK Wyatt Mol Vis 6 (1), 79-84, 2000 | 29 | 2000 |