| The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability S Barth, J Nesper, PA Hasgall, R Wirthner, KJ Nytko, F Edlich, ... Molecular and cellular biology, 2007 | 141 | 2007 |
| Vitamin C is dispensable for oxygen sensing in vivo KJ Nytko, N Maeda, P Schläfli, P Spielmann, RH Wenger, DP Stiehl Blood, The Journal of the American Society of Hematology 117 (20), 5485-5493, 2011 | 86 | 2011 |
| Aberrant Lck signal via CD28 costimulation augments antigen-specific functionality and tumor control by redirected T cells with PD-1 blockade in humanized mice P Gulati, J Rühl, A Kannan, M Pircher, P Schuberth, KJ Nytko, M Pruschy, ... Clinical Cancer Research 24 (16), 3981-3993, 2018 | 63 | 2018 |
| Regulated function of the prolyl-4-hydroxylase domain (PHD) oxygen sensor proteins KJ Nytko, P Spielmann, G Camenisch, RH Wenger, DP Stiehl Antioxidants & redox signaling 9 (9), 1329-1338, 2007 | 53 | 2007 |
| The novel microtubule targeting agent BAL101553 in combination with radiotherapy in treatment-refractory tumor models A Sharma, A Broggini-Tenzer, V Vuong, A Messikommer, KJ Nytko, ... Radiotherapy and Oncology 124 (3), 433-438, 2017 | 46 | 2017 |
| Mutations of BRCA2 in canine mammary tumors and their targeting potential in clinical therapy P Thumser-Henner, KJ Nytko, C Rohrer Bley BMC veterinary research 16 (1), 30, 2020 | 45 | 2020 |
| Congenital erythrocytosis associated with gain-of-function HIF2A gene mutations and erythropoietin levels in the normal range S Perrotta, DP Stiehl, F Punzo, S Scianguetta, A Borriello, D Bencivenga, ... haematologica 98 (10), 1624, 2013 | 44 | 2013 |
| The oxygen sensor PHD3 limits glycolysis under hypoxia via direct binding to pyruvate kinase N Chen, O Rinner, D Czernik, KJ Nytko, D Zheng, DP Stiehl, N Zamboni, ... Cell research 21 (6), 983-986, 2011 | 39 | 2011 |
| The hypoxia-activated prodrug evofosfamide in combination with multiple regimens of radiotherapy KJ Nytko, I Grgic, S Bender, J Ott, M Guckenberger, O Riesterer, ... Oncotarget 8 (14), 23702, 2017 | 32 | 2017 |
| Combined treatment strategies for microtubule stabilizing agent-resistant tumors A Broggini-Tenzer, A Sharma, KJ Nytko, S Bender, V Vuong, K Orlowski, ... Journal of the National Cancer Institute 107 (4), dju504, 2015 | 24 | 2015 |
| Cell line-specific efficacy of thermoradiotherapy in human and canine cancer cells in vitro KJ Nytko, P Thumser-Henner, MS Weyland, S Scheidegger, CR Bley PloS one 14 (5), e0216744, 2019 | 21 | 2019 |
| Dynamic in vivo profiling of DNA damage and repair after radiotherapy using canine patients as a model N Schulz, H Chaachouay, KJ Nytko, MS Weyland, M Roos, RM Füchslin, ... International journal of molecular sciences 18 (6), 1176, 2017 | 19 | 2017 |
| 202 The novel microtubule-destabilizing drug BAL101553 (prodrug of BAL27862) sensitizes a treatment refractory tumor model to ionizing radiation A Broggini-Tenzer, F Bachmann, V Vuong, A Messikommer, ... European Journal of Cancer, 65-66, 2014 | 18 | 2014 |
| Defective nuclear entry of hydrolases prevents neutrophil extracellular trap formation in patients with chronic granulomatous disease S Romao, ET Puente, KJ Nytko, U Siler, C Münz, J Reichenbach Journal of Allergy and Clinical Immunology 136 (6), 1703-1706. e5, 2015 | 13 | 2015 |
| Role of HSP70 in response to (thermo) radiotherapy: analysis of gene expression in canine osteosarcoma cells by RNA-seq KJ Nytko, P Thumser-Henner, G Russo, MS Weyland, C Rohrer Bley Scientific reports 10 (1), 12779, 2020 | 7 | 2020 |
| Cell Res N Chen, O Rinner, D Czernik, KJ Nytko, D Zheng, DP Stiehl, N Zamboni, ... Published online April 12 (2011), 10.1038, 2011 | 7 | 2011 |
| Temozolomide is additive with cytotoxic effect of irradiation in canine glioma cell lines NS Tresch, D Fuchs, L Morandi, C Tonon, C Rohrer Bley, KJ Nytko Veterinary Medicine and Science 7 (6), 2124-2134, 2021 | 6 | 2021 |
| Methadone does not potentiate the effect of doxorubicin in canine tumour cell lines C Cueni, KJ Nytko, P Thumser‐Henner, MS Weyland, C Rohrer Bley Veterinary medicine and science 6 (3), 283-289, 2020 | 5 | 2020 |
| Holistic View on Cell Survival and DNA Damage: How Model‐Based Data Analysis Supports Exploration of Dynamics in Biological Systems MS Weyland, P Thumser-Henner, KJ Nytko, C Rohrer Bley, S Ulzega, ... Computational and mathematical methods in medicine 2020 (1), 5972594, 2020 | 5 | 2020 |
| The peptidyl-prolyl cis/trans isomerase FKBP38 determines HIF prolyl-4-hydroxylase PHD2 protein stability S Barth, J Nesper, PA Hasgall, R Wirthner, KJ Nytko, F Edlich, ... Mol Cell Biol 27, 3758-3768, 2007 | 4 | 2007 |
