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Christopher Whidbey
Christopher Whidbey
Assistant Professor, Department of Chemistry, Seattle University
Verified email at seattleu.edu
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Cited by
Cited by
Year
A hemolytic pigment of Group B Streptococcus allows bacterial penetration of human placenta
C Whidbey, MI Harrell, K Burnside, L Ngo, AK Becraft, LM Iyer, L Aravind, ...
Journal of Experimental Medicine 210 (6), 1265-1281, 2013
2142013
A streptococcal lipid toxin induces membrane permeabilization and pyroptosis leading to fetal injury
C Whidbey, J Vornhagen, C Gendrin, E Boldenow, JM Samson, ...
EMBO molecular medicine 7 (4), 488-505, 2015
1032015
Bacterial hyaluronidase promotes ascending GBS infection and preterm birth
J Vornhagen, P Quach, E Boldenow, S Merillat, C Whidbey, LY Ngo, ...
MBio 7 (3), 10.1128/mbio. 00781-16, 2016
1012016
Group B Streptococcus circumvents neutrophils and neutrophil extracellular traps during amniotic cavity invasion and preterm labor
E Boldenow, C Gendrin, L Ngo, C Bierle, J Vornhagen, M Coleman, ...
Science immunology 1 (4), eaah4576, 2016
982016
Group B streptococcus exploits vaginal epithelial exfoliation for ascending infection
J Vornhagen, B Armistead, V Santana-Ufret, C Gendrin, S Merillat, ...
The Journal of clinical investigation 128 (5), 1985-1999, 2018
792018
Photochemical induced changes of in vitro estrogenic activity of steroid hormones
CM Whidbey, KE Daumit, TH Nguyen, DD Ashworth, JCC Davis, DE Latch
Water research 46 (16), 5287-5296, 2012
682012
Mast cell degranulation by a hemolytic lipid toxin decreases GBS colonization and infection
C Gendrin, J Vornhagen, L Ngo, C Whidbey, E Boldenow, ...
Science advances 1 (6), e1400225, 2015
622015
A probe-enabled approach for the selective isolation and characterization of functionally active subpopulations in the gut microbiome
C Whidbey, NC Sadler, RN Nair, RF Volk, AJ DeLeon, LM Bramer, ...
Journal of the American Chemical Society 141 (1), 42-47, 2018
552018
Kinase Inhibitors that Increase the Sensitivity of Methicillin Resistant Staphylococcus aureus to β-Lactam Antibiotics
J Vornhagen, K Burnside, C Whidbey, J Berry, X Qin, L Rajagopal
Pathogens 4 (4), 708-721, 2015
332015
A continuous fluorescence assay for simple quantification of bile salt hydrolase activity in the gut microbiome
KR Brandvold, JM Weaver, C Whidbey, AT Wright
Scientific Reports 9 (1), 1359, 2019
292019
A nonhemolytic group B Streptococcus strain exhibits hypervirulence
C Gendrin, J Vornhagen, B Armistead, P Singh, C Whidbey, S Merillat, ...
The Journal of infectious diseases 217 (6), 983-987, 2018
292018
Activity-based protein profiling—enabling multimodal functional studies of microbial communities
C Whidbey, AT Wright
Activity-based protein profiling, 1-21, 2019
262019
Lipid analogs reveal features critical for hemolysis and diminish granadaene mediated Group B Streptococcus infection
B Armistead, P Herrero-Foncubierta, M Coleman, P Quach, C Whidbey, ...
Nature communications 11 (1), 1502, 2020
242020
The cyl Genes Reveal the Biosynthetic and Evolutionary Origins of the Group B Streptococcus Hemolytic Lipid, Granadaene
B Armistead, C Whidbey, LM Iyer, P Herrero-Foncubierta, P Quach, ...
Frontiers in microbiology 10, 3123, 2020
242020
Activity‐Based Protein Profiling of Bile Salt Hydrolysis in the Human Gut Microbiome with Beta‐Lactam or Acrylamide‐Based Probes
KR Brandvold, CJ Miller, RF Volk, BJ Killinger, C Whidbey, AT Wright
ChemBioChem 22 (8), 1448-1455, 2021
142021
The sensor histidine kinase RgfC affects group B streptococcal virulence factor expression independent of its response regulator RgfA
C Gendrin, A Lembo, C Whidbey, K Burnside, J Berry, L Ngo, A Banerjee, ...
Infection and Immunity 83 (3), 1078-1088, 2015
142015
A hyperhemolytic/hyperpigmented group B Streptococcus strain with a CovR mutation isolated from an adolescent patient with sore throat
C Whidbey, K Burnside, RM Martinez, C Gendrin, J Vornhagen, A Frando, ...
Clinical research in infectious diseases 2 (2), 2015
142015
Activity-based protein profiling identifies alternating activation of enzymes involved in the bifidobacterium shunt pathway or mucin degradation in the gut microbiome response …
BJ Killinger, C Whidbey, NC Sadler, AJ DeLeon, N Munoz, YM Kim, ...
npj Biofilms and Microbiomes 8 (1), 60, 2022
132022
Characterization of vaginal microbial enzymes identifies amylopullulanases that support growth of Lactobacillus crispatus on glycogen
BM Woolston, DJ Jenkins, MI Hood-Pishchany, SR Nahoum, EP Balskus
BioRxiv, 2021.07. 19.452977, 2021
132021
Exploring the pregnant guinea pig as a model for group B streptococcus intrauterine infection
MI Harrell, K Burnside, C Whidbey, J Vornhagen, KMA Waldorf, ...
Journal of infectious diseases and medicine 2 (2), 2017
132017
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