| Crocus sativus Extract Tightens the Blood-Brain Barrier, Reduces Amyloid β Load and Related Toxicity in 5XFAD Mice YS Batarseh, SS Bharate, V Kumar, A Kumar, RA Vishwakarma, ... ACS chemical neuroscience 8 (8), 1756-1766, 2017 | 94 | 2017 |
| Discovery of a marine-derived bis-indole alkaloid fascaplysin, as a new class of potent P-glycoprotein inducer and establishment of its structure–activity relationship S Manda, S Sharma, A Wani, P Joshi, V Kumar, SK Guru, SS Bharate, ... European journal of medicinal chemistry 107, 1-11, 2016 | 78 | 2016 |
| Design of novel 3-pyrimidinylazaindole CDK2/9 inhibitors with potent in vitro and in vivo antitumor efficacy in a triple-negative breast cancer model U Singh, G Chashoo, SU Khan, P Mahajan, A Nargotra, G Mahajan, ... Journal of medicinal chemistry 60 (23), 9470-9489, 2017 | 67 | 2017 |
| Determining partition coefficient (Log P), distribution coefficient (Log D) and ionization constant (pKa) in early drug discovery S S Bharate, V Kumar, R A Vishwakarma Combinatorial chemistry & high throughput screening 19 (6), 461-469, 2016 | 67 | 2016 |
| Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines NJ Horley, KJM Beresford, T Chawla, GJP McCann, KC Ruparelia, ... European journal of medicinal chemistry 129, 159-174, 2017 | 49 | 2017 |
| Discovery and preclinical development of IIIM-290, an orally active potent cyclin-dependent kinase inhibitor SB Bharate, V Kumar, SK Jain, MJ Mintoo, SK Guru, VK Nuthakki, ... Journal of medicinal chemistry 61 (4), 1664-1687, 2018 | 48 | 2018 |
| A chromatography-free isolation of rohitukine from leaves of Dysoxylum binectariferum: Evaluation for in vitro cytotoxicity, Cdk inhibition and physicochemical properties V Kumar, SK Guru, SK Jain, P Joshi, SG Gandhi, SB Bharate, S Bhushan, ... Bioorganic & medicinal chemistry letters 26 (15), 3457-3463, 2016 | 43 | 2016 |
| 6-Aryl substituted 4-(4-cyanomethyl) phenylamino quinazolines as a new class of isoform-selective PI3K-alpha inhibitors RR Yadav, SK Guru, P Joshi, G Mahajan, MJ Mintoo, V Kumar, ... European journal of medicinal chemistry 122, 731-743, 2016 | 42 | 2016 |
| Preclinical Development of Crocus sativus-Based Botanical Lead IIIM-141 for Alzheimer’s Disease: Chemical Standardization, Efficacy, Formulation Development … SS Bharate, V Kumar, G Singh, A Singh, M Gupta, D Singh, A Kumar, ... ACS Omega 3 (8), 9572-9585, 2018 | 40 | 2018 |
| Anti-inflammatory chromone alkaloids and glycoside from Dysoxylum binectariferum V Kumar, M Gupta, SG Gandhi, SS Bharate, A Kumar, RA Vishwakarma, ... Tetrahedron Letters 58 (42), 3974-3978, 2017 | 40 | 2017 |
| Discovery of 7-(Prolinol-N-yl)-2-phenylamino-thiazolo[5,4-d]pyrimidines as Novel Non-Nucleoside Partial Agonists for the A2A Adenosine Receptor: Prediction … SB Bharate, B Singh, S Kachler, A Oliveira, V Kumar, SS Bharate, ... Journal of medicinal chemistry 59 (12), 5922-5928, 2016 | 26 | 2016 |
| Binary and ternary solid dispersions of an anticancer preclinical lead, IIIM-290: In vitro and in vivo studies V Kumar, MJ Mintoo, DM Mondhe, SB Bharate, RA Vishwakarma, ... International Journal of Pharmaceutics, 118683, 2019 | 25 | 2019 |
| Modulating lipophilicity of rohitukine via prodrug approach: Preparation, characterization, and in vitro enzymatic hydrolysis in biorelevant media V Kumar, SS Bharate, RA Vishwakarma European Journal of Pharmaceutical Sciences 92, 203-211, 2016 | 24 | 2016 |
| Synthesis, pH dependent, plasma and enzymatic stability of bergenin prodrugs for potential use against rheumatoid arthritis R Singh, V Kumar, SS Bharate, RA Vishwakarma Bioorganic & medicinal chemistry 25 (20), 5513-5521, 2017 | 23 | 2017 |
| Discovery and preclinical development of IIIM-160, a Bergenia ciliata-based anti-inflammatory and anti-arthritic botanical drug candidate SB Bharate, V Kumar, SS Bharate, B Singh, G Singh, A Singh, M Gupta, ... Journal of integrative medicine 17 (3), 192-204, 2019 | 21 | 2019 |
| Selection of a water-soluble salt form of a preclinical candidate, IIIM-290: multiwell-plate salt screening and characterization V Kumar, SB Bharate, RA Vishwakarma, SS Bharate ACS omega 3 (7), 8365-8377, 2018 | 16 | 2018 |
| Evaluation of rohitukine-enriched fraction of Dysoxylum binectariferum Hook. f.(leaves) as anti-arthritic phytopharmaceutical candidate: Chemical standardization, in-vivo … V Kumar, SS Bharate, D Bhurta, M Gupta, SG Gandhi, D Singh, S Jaglan, ... Journal of Ethnopharmacology, 112758, 2020 | 11 | 2020 |
| γ Peptide Nucleic Acid-Based miR-122 Inhibition Rescues Vascular Endothelial Dysfunction in Mice Fed a High-Fat Diet RR Gaddam, K Dhuri, YR Kim, JS Jacobs, V Kumar, Q Li, K Irani, R Bahal, ... Journal of Medicinal Chemistry, 2022 | 9 | 2022 |
| Impurity profiling of anticancer preclinical candidate, IIIM-290 V Kumar, D Bhurta, A Sharma, P Kumar, SB Bharate, RA Vishwakarma, ... Journal of pharmaceutical and biomedical analysis 166, 1-5, 2019 | 9 | 2019 |
| Head on Comparison of Self‐and Nano‐Assemblies of Gamma Peptide Nucleic Acid Amphiphiles S Malik, V Kumar, CH Liu, KC Shih, S Krueger, MP Nieh, R Bahal Advanced Functional Materials, 2109552, 2021 | 8 | 2021 |
