Role for NLRP3 inflammasome–mediated, IL-1β–dependent responses in severe, steroid-resistant asthma RY Kim, JW Pinkerton, AT Essilfie, AAB Robertson, KJ Baines, AC Brown, ... American journal of respiratory and critical care medicine 196 (3), 283-297, 2017 | 395 | 2017 |
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages MC Runtsch, S Angiari, A Hooftman, R Wadhwa, Y Zhang, Y Zheng, ... Cell metabolism 34 (3), 487-501. e8, 2022 | 151 | 2022 |
Airway remodelling and inflammation in asthma are dependent on the extracellular matrix protein fibulin‐1c G Liu, MA Cooley, PM Nair, C Donovan, AC Hsu, AG Jarnicki, TJ Haw, ... The Journal of pathology 243 (4), 510-523, 2017 | 112 | 2017 |
Critical role for iron accumulation in the pathogenesis of fibrotic lung disease MK Ali, RY Kim, AC Brown, C Donovan, KS Vanka, JR Mayall, G Liu, ... The Journal of pathology 251 (1), 49-62, 2020 | 90 | 2020 |
Murine models of infectious exacerbations of airway inflammation MR Starkey, AG Jarnicki, AT Essilfie, SL Gellatly, RY Kim, AC Brown, ... Current opinion in pharmacology 13 (3), 337-344, 2013 | 78 | 2013 |
Mucosal production of uric acid by airway epithelial cells contributes to particulate matter-induced allergic sensitization MJ Gold, PR Hiebert, HY Park, D Stefanowicz, A Le, MR Starkey, A Deane, ... Mucosal immunology 9 (3), 809-820, 2016 | 74 | 2016 |
COPD is characterized by increased detection of Haemophilus influenzae, Streptococcus pneumoniae and a deficiency of Bacillus species JL Simpson, KJ Baines, JC Horvat, AT Essilfie, AC Brown, M Tooze, ... Respirology 21 (4), 697-704, 2016 | 69 | 2016 |
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma MK Ali, RY Kim, AC Brown, JR Mayall, R Karim, JW Pinkerton, G Liu, ... European Respiratory Journal 55 (4), 2020 | 56 | 2020 |
Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma JW Pinkerton, RY Kim, AC Brown, BE Rae, C Donovan, JR Mayall, ... Journal of Allergy and Clinical Immunology 149 (4), 1270-1280, 2022 | 38 | 2022 |
Glycemic variability in diabetes increases the severity of influenza RJ Marshall, P Armart, KD Hulme, KY Chew, AC Brown, PM Hansbro, ... MBio 11 (2), 10.1128/mbio. 02841-19, 2020 | 37 | 2020 |
Pneumococcal components induce regulatory T cells that attenuate the development of allergic airways disease by deviating and suppressing the immune response to allergen AN Thorburn, AC Brown, PM Nair, N Chevalier, PS Foster, PG Gibson, ... The Journal of Immunology 191 (8), 4112-4120, 2013 | 31 | 2013 |
Programmed Death Ligand 1 Promotes Early-Life Chlamydia Respiratory Infection–Induced Severe Allergic Airway Disease MR Starkey, DH Nguyen, AC Brown, AT Essilfie, RY Kim, H Yagita, ... American journal of respiratory cell and molecular biology 54 (4), 493-503, 2016 | 29 | 2016 |
Human β‐defensin‐2 suppresses key features of asthma in murine models of allergic airways disease JW Pinkerton, RY Kim, L Koeninger, NS Armbruster, NG Hansbro, ... Clinical & Experimental Allergy 51 (1), 120-131, 2021 | 24 | 2021 |
Visualization of endogenous p27 and Ki67 reveals the importance of a c-Myc-driven metabolic switch in promoting survival of quiescent cancer cells T La, S Chen, T Guo, XH Zhao, L Teng, D Li, M Carnell, YY Zhang, ... Theranostics 11 (19), 9605, 2021 | 24 | 2021 |
Endoplasmic reticulum-unfolded protein response signalling is altered in severe eosinophilic and neutrophilic asthma PS Pathinayake, DW Waters, KS Nichol, AC Brown, AT Reid, ACY Hsu, ... Thorax 77 (5), 443-451, 2022 | 22 | 2022 |
Polycomb repressive complex 2 is a critical mediator of allergic inflammation CR Keenan, N Iannarella, AL Garnham, AC Brown, RY Kim, JC Horvat, ... Jci Insight 4 (10), 2019 | 22 | 2019 |
Sex steroids induce membrane stress responses and virulence properties in Pseudomonas aeruginosa C Vidaillac, VFL Yong, MS Aschtgen, J Qu, S Yang, G Xu, ZJ Seng, ... MBio 11 (5), 10.1128/mbio. 01774-20, 2020 | 18 | 2020 |
Programming of the lung in early life by bacterial infections predisposes to chronic respiratory disease MR Starkey, DH Nguyen, RY Kim, PM Nair, AC Brown, AT Essifie, ... Clinical Obstetrics and Gynecology 56 (3), 566-576, 2013 | 16 | 2013 |
Effect of obesity on airway and systemic inflammation in adults with asthma: a systematic review and meta-analysis HA Scott, SHM Ng, RF McLoughlin, SR Valkenborghs, P Nair, AC Brown, ... Thorax 78 (10), 957-965, 2023 | 14 | 2023 |
Aim2 suppresses cigarette smoke‐induced neutrophil recruitment, neutrophil caspase‐1 activation and anti‐Ly6G‐mediated neutrophil depletion C Donovan, RY Kim, I Galvao, AG Jarnicki, AC Brown, B Jones‐Freeman, ... Immunology and Cell Biology 100 (4), 235-249, 2022 | 11 | 2022 |