A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets N Deng, LK Goh, H Wang, K Das, J Tao, IB Tan, S Zhang, M Lee, J Wu, ... Gut 61 (5), 673-684, 2012 | 719 | 2012 |
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes ZJ Zang, I Cutcutache, SL Poon, SL Zhang, JR McPherson, J Tao, ... Nature genetics 44 (5), 570-574, 2012 | 702 | 2012 |
ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer M Van Geldermalsen, Q Wang, R Nagarajah, AD Marshall, A Thoeng, ... Oncogene 35 (24), 3201-3208, 2016 | 575 | 2016 |
Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase inhibitors and 5-fluorouracil Z Lei, IB Tan, K Das, N Deng, H Zouridis, S Pattison, C Chua, Z Feng, ... Gastroenterology 145 (3), 554-565, 2013 | 477 | 2013 |
Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapy IB Tan, T Ivanova, KH Lim, CW Ong, N Deng, J Lee, SH Tan, J Wu, ... Gastroenterology 141 (2), 476-485. e11, 2011 | 422 | 2011 |
Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer AS Cazet, MN Hui, BL Elsworth, SZ Wu, D Roden, CL Chan, JN Skhinas, ... Nature communications 9 (1), 2897, 2018 | 377 | 2018 |
Genomic Loss of miR-486 Regulates Tumor Progression and the OLFM4 Antiapoptotic Factor in Gastric Cancer HK Oh, ALK Tan, K Das, CH Ooi, NT Deng, IBH Tan, E Beillard, J Lee, ... Clinical cancer research 17 (9), 2657-2667, 2011 | 218 | 2011 |
Methylation subtypes and large-scale epigenetic alterations in gastric cancer H Zouridis, N Deng, T Ivanova, Y Zhu, B Wong, D Huang, YH Wu, Y Wu, ... Science translational medicine 4 (156), 156ra140-156ra140, 2012 | 207 | 2012 |
Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development NY Chia, N Deng, K Das, D Huang, L Hu, Y Zhu, KH Lim, MH Lee, J Wu, ... Gut 64 (5), 707-719, 2015 | 182 | 2015 |
Whole-genome reconstruction and mutational signatures in gastric cancer N Nagarajan, D Bertrand, AM Hillmer, ZJ Zang, F Yao, PÉ Jacques, ... Genome biology 13, 1-10, 2012 | 140 | 2012 |
CD44-SLC1A2 gene fusions in gastric cancer J Tao, NT Deng, K Ramnarayanan, B Huang, HK Oh, SH Leong, SS Lim, ... Science translational medicine 3 (77), 77ra30-77ra30, 2011 | 90 | 2011 |
Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements M Muratani, N Deng, WF Ooi, SJ Lin, M Xing, C Xu, A Qamra, ST Tay, ... Nature communications 5 (1), 4361, 2014 | 82 | 2014 |
OCT1 is a determinant of synbindin-related ERK signalling with independent prognostic significance in gastric cancer J Qian, X Kong, N Deng, P Tan, H Chen, J Wang, Z Li, Y Hu, W Zou, J Xu, ... Gut 64 (1), 37-48, 2015 | 77 | 2015 |
Identification of a TLR2-regulated gene signature associated with tumor cell growth in gastric cancer AC West, K Tang, H Tye, L Yu, N Deng, M Najdovska, SJ Lin, JJ Balic, ... Oncogene 36 (36), 5134-5144, 2017 | 69 | 2017 |
Mutually exclusive FGFR2, HER2, and KRAS gene amplifications in gastric cancer revealed by multicolour FISH K Das, B Gunasegaran, IB Tan, N Deng, KH Lim, P Tan Cancer letters 353 (2), 167-175, 2014 | 66 | 2014 |
Integrated molecular profiling of human gastric cancer identifies DDR2 as a potential regulator of peritoneal dissemination J Kurashige, T Hasegawa, A Niida, K Sugimachi, N Deng, K Mima, R Uchi, ... Scientific reports 6 (1), 22371, 2016 | 65 | 2016 |
MASTL overexpression promotes chromosome instability and metastasis in breast cancer S Rogers, RA McCloy, BL Parker, D Gallego-Ortega, AMK Law, VT Chin, ... Oncogene 37 (33), 4518-4533, 2018 | 60 | 2018 |
The atypical kinase RIOK1 promotes tumor growth and invasive behavior F Weinberg, N Reischmann, L Fauth, S Taromi, J Mastroianni, M Köhler, ... EBioMedicine 20, 79-97, 2017 | 51 | 2017 |
MicroRNA profiling of the pubertal mouse mammary gland identifies miR-184 as a candidate breast tumour suppressor gene YW Phua, A Nguyen, DL Roden, B Elsworth, N Deng, I Nikolic, J Yang, ... Breast Cancer Research 17, 1-18, 2015 | 51 | 2015 |
Toll‐like receptor 2 regulates metabolic reprogramming in gastric cancer via superoxide dismutase 2 YD Liu, L Yu, L Ying, J Balic, H Gao, NT Deng, A West, F Yan, CB Ji, ... International journal of cancer 144 (12), 3056-3069, 2019 | 49 | 2019 |