Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas KS Aboody, A Brown, NG Rainov, KA Bower, S Liu, W Yang, JE Small, ... Proceedings of the National Academy of Sciences 97 (23), 12846-12851, 2000 | 1687 | 2000 |
The origin of the cancer stem cell: current controversies and new insights R Bjerkvig, BB Tysnes, KS Aboody, J Najbauer, AJA Terzis Nature Reviews Cancer 5 (11), 899-904, 2005 | 843 | 2005 |
Stem and progenitor cell-mediated tumor selective gene therapy KS Aboody, J Najbauer, MK Danks Gene therapy 15 (10), 739-752, 2008 | 373 | 2008 |
Brain tumor tropism of transplanted human neural stem cells is induced by vascular endothelial growth factor NO Schmidt, W Przylecki, W Yang, M Ziu, YD Teng, SU Kim, PM Black, ... Neoplasia 7 (6), 623-630, 2005 | 271 | 2005 |
Neural stem cell–mediated enzyme/prodrug therapy for glioma: Preclinical studies KS Aboody, J Najbauer, MZ Metz, M D’Apuzzo, M Gutova, AJ Annala, ... Science translational medicine 5 (184), 184ra59-184ra59, 2013 | 268 | 2013 |
Human neural stem cells target experimental intracranial medulloblastoma and deliver a therapeutic gene leading to tumor regression SK Kim, SU Kim, IH Park, JH Bang, KS Aboody, KC Wang, BK Cho, M Kim, ... Clinical Cancer Research 12 (18), 5550-5556, 2006 | 262 | 2006 |
Intravascular delivery of neural stem cell lines to target intracranial and extracranial tumors of neural and non-neural origin AB Brown, W Yang, NO Schmidt, R Carroll, KK Leishear, NG Rainov, ... Human gene therapy 14 (18), 1777-1785, 2003 | 236 | 2003 |
Translating stem cell studies to the clinic for CNS repair: current state of the art and the need for a Rosetta stone K Aboody, A Capela, N Niazi, JH Stern, S Temple Neuron 70 (4), 597-613, 2011 | 232 | 2011 |
Global gene and cell replacement strategies via stem cells KI Park, J Ourednik, V Ourednik, RM Taylor, KS Aboody, KI Auguste, ... Gene therapy 9 (10), 613-624, 2002 | 218 | 2002 |
Neural stem cell tropism to glioma: critical role of tumor hypoxia D Zhao, J Najbauer, E Garcia, MZ Metz, M Gutova, CA Glackin, SU Kim, ... Molecular Cancer Research 6 (12), 1819-1829, 2008 | 217 | 2008 |
Neural precursor cells for delivery of replication-conditional HSV-1 vectors to intracerebral gliomas U Herrlinger, C Woiciechowski, M Sena-Esteves, KS Aboody, AH Jacobs, ... Molecular Therapy 1 (4), 347-357, 2000 | 202 | 2000 |
Targeting of melanoma brain metastases using engineered neural stem/progenitor cells KS Aboody, J Najbauer, NO Schmidt, W Yang, JK Wu, Y Zhuge, ... Neuro-oncology 8 (2), 119-126, 2006 | 199 | 2006 |
Vascular endothelial growth factor A contributes to glioma-induced migration of human marrow stromal cells (hMSC) C Schichor, T Birnbaum, N Etminan, O Schnell, S Grau, S Miebach, ... Experimental neurology 199 (2), 301-310, 2006 | 194 | 2006 |
Chlorotoxin-directed CAR T cells for specific and effective targeting of glioblastoma D Wang, R Starr, WC Chang, B Aguilar, D Alizadeh, SL Wright, X Yang, ... Science translational medicine 12 (533), eaaw2672, 2020 | 190 | 2020 |
Identification of uPAR-positive chemoresistant cells in small cell lung cancer M Gutova, J Najbauer, A Gevorgyan, MZ Metz, Y Weng, CC Shih, ... PloS one 2 (2), e243, 2007 | 178 | 2007 |
Neural stem cell-mediated intratumoral delivery of gold nanorods improves photothermal therapy R Mooney, L Roma, D Zhao, D Van Haute, E Garcia, SU Kim, AJ Annala, ... ACS nano 8 (12), 12450-12460, 2014 | 176 | 2014 |
Tumor-derived chemokine MCP-1/CCL2 is sufficient for mediating tumor tropism of adoptively transferred T cells CE Brown, RP Vishwanath, B Aguilar, R Starr, J Najbauer, KS Aboody, ... The Journal of Immunology 179 (5), 3332-3341, 2007 | 174 | 2007 |
Neural stem cell–based anticancer gene therapy: a first-in-human study in recurrent high-grade glioma patients J Portnow, TW Synold, B Badie, R Tirughana, SF Lacey, M D'Apuzzo, ... Clinical Cancer Research 23 (12), 2951-2960, 2017 | 159 | 2017 |
Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma MK Danks, KJ Yoon, RA Bush, JS Remack, M Wierdl, L Tsurkan, SU Kim, ... Cancer research 67 (1), 22-25, 2007 | 157 | 2007 |
Neural stem cell-based cell carriers enhance therapeutic efficacy of an oncolytic adenovirus in an orthotopic mouse model of human glioblastoma AU Ahmed, B Thaci, NG Alexiades, Y Han, S Qian, F Liu, IV Balyasnikova, ... Molecular Therapy 19 (9), 1714-1726, 2011 | 155 | 2011 |