Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor P Tontonoz, E Hu, BM Spiegelman Cell 79 (7), 1147-1156, 1994 | 4534 | 1994 |
15-deoxy-Δ12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ BM Forman, P Tontonoz, J Chen, RP Brun, BM Spiegelman, RM Evans Cell 83 (5), 803-812, 1995 | 3744 | 1995 |
mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. P Tontonoz, E Hu, RA Graves, AI Budavari, BM Spiegelman Genes & development 8 (10), 1224-1234, 1994 | 2906 | 1994 |
Fat and beyond: the diverse biology of PPARγ P Tontonoz, BM Spiegelman Annu. Rev. Biochem. 77 (1), 289-312, 2008 | 2439 | 2008 |
PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL P Tontonoz, L Nagy, JGA Alvarez, VA Thomazy, RM Evans Cell 93 (2), 241-252, 1998 | 2383 | 1998 |
Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ L Nagy, P Tontonoz, JGA Alvarez, H Chen, RM Evans Cell 93 (2), 229-240, 1998 | 2359 | 1998 |
A PPARγ-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis A Chawla, WA Boisvert, CH Lee, BA Laffitte, Y Barak, SB Joseph, D Liao, ... Molecular cell 7 (1), 161-171, 2001 | 1729 | 2001 |
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors SB Joseph, A Castrillo, BA Laffitte, DJ Mangelsdorf, P Tontonoz Nature medicine 9 (2), 213-219, 2003 | 1473 | 2003 |
PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation A Chawla, Y Barak, L Nagy, D Liao, P Tontonoz, RM Evans Nature medicine 7 (1), 48-52, 2001 | 1357 | 2001 |
Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRα A Venkateswaran, BA Laffitte, SB Joseph, PA Mak, DC Wilpitz, ... Proceedings of the National Academy of Sciences 97 (22), 12097-12102, 2000 | 1221 | 2000 |
Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor HR Kast, B Goodwin, PT Tarr, SA Jones, AM Anisfeld, CM Stoltz, ... Journal of Biological Chemistry 277 (4), 2908-2915, 2002 | 1135 | 2002 |
ApoE promotes the proteolytic degradation of Aβ Q Jiang, CYD Lee, S Mandrekar, B Wilkinson, P Cramer, N Zelcer, ... Neuron 58 (5), 681-693, 2008 | 1130 | 2008 |
Synthetic LXR ligand inhibits the development of atherosclerosis in mice SB Joseph, E McKilligin, L Pei, MA Watson, AR Collins, BA Laffitte, ... Proceedings of the National Academy of Sciences 99 (11), 7604-7609, 2002 | 1130 | 2002 |
Liver X receptors as integrators of metabolic and inflammatory signaling N Zelcer, P Tontonoz The Journal of clinical investigation 116 (3), 607-614, 2006 | 1125 | 2006 |
Terminal differentiation of human breast cancer through PPARγ E Mueller, P Sarraf, P Tontonoz, RM Evans, KJ Martin, M Zhang, ... Molecular cell 1 (3), 465-470, 1998 | 1116 | 1998 |
Integration of metabolism and inflammation by lipid-activated nuclear receptors SJ Bensinger, P Tontonoz Nature 454 (7203), 470-477, 2008 | 982 | 2008 |
LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor N Zelcer, C Hong, R Boyadjian, P Tontonoz Science 325 (5936), 100-104, 2009 | 965 | 2009 |
Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors SB Joseph, BA Laffitte, PH Patel, MA Watson, KE Matsukuma, R Walczak, ... Journal of Biological Chemistry 277 (13), 11019-11025, 2002 | 937 | 2002 |
LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes BA Laffitte, JJ Repa, SB Joseph, DC Wilpitz, HR Kast, DJ Mangelsdorf, ... Proceedings of the National Academy of Sciences 98 (2), 507-512, 2001 | 868 | 2001 |
Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor γ and the retinoid X receptor P Tontonoz, S Singer, BM Forman, P Sarraf, JA Fletcher, CDM Fletcher, ... Proceedings of the National Academy of Sciences 94 (1), 237-241, 1997 | 839 | 1997 |