| A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes DG MacArthur, S Balasubramanian, A Frankish, N Huang, J Morris, ... Science 335 (6070), 823-828, 2012 | 1394 | 2012 |
| The UK10K project identifies rare variants in health and disease Statistics group Ciampi Antonio 8 Greenwood Celia MT (co-chair) 7 8 14 19 ... Nature 526 (7571), 82-90, 2015 | 1107 | 2015 |
| Enhanced detection of circulating tumor DNA by fragment size analysis F Mouliere, D Chandrananda, AM Piskorz, EK Moore, J Morris, ... Science translational medicine 10 (466), eaat4921, 2018 | 876 | 2018 |
| Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage I Angulo, O Vadas, F Garçon, E Banham-Hall, V Plagnol, TR Leahy, ... Science 342 (6160), 866-871, 2013 | 654 | 2013 |
| Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 T Cooks, IS Pateras, LM Jenkins, KM Patel, AI Robles, J Morris, ... Nature communications 9 (1), 771, 2018 | 453 | 2018 |
| High fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development D Lin, AW Wyatt, H Xue, Y Wang, X Dong, A Haegert, R Wu, S Brahmbhatt, ... Cancer research 74 (4), 1272-1283, 2014 | 406 | 2014 |
| Effective drug combinations in breast, colon and pancreatic cancer cells P Jaaks, EA Coker, DJ Vis, O Edwards, EF Carpenter, SM Leto, L Dwane, ... Nature 603 (7899), 166-173, 2022 | 237 | 2022 |
| ctDNA monitoring using patient-specific sequencing and integration of variant reads JCM Wan, K Heider, D Gale, S Murphy, E Fisher, F Mouliere, ... Science translational medicine 12 (548), eaaz8084, 2020 | 154 | 2020 |
| Detection of cell‐free DNA fragmentation and copy number alterations in cerebrospinal fluid from glioma patients F Mouliere, R Mair, D Chandrananda, F Marass, CG Smith, J Su, J Morris, ... EMBO molecular medicine 10 (12), e9323, 2018 | 154 | 2018 |
| optiCall: a robust genotype-calling algorithm for rare, low-frequency and common variants TS Shah, JZ Liu, JAB Floyd, JA Morris, N Wirth, JC Barrett, CA Anderson Bioinformatics 28 (12), 1598-1603, 2012 | 128 | 2012 |
| Association of plasma and urinary mutant DNA with clinical outcomes in muscle invasive bladder cancer KM Patel, KE Van Der Vos, CG Smith, F Mouliere, D Tsui, J Morris, ... Scientific Reports 7 (1), 5554, 2017 | 104 | 2017 |
| Pan-cancer proteomic map of 949 human cell lines E Gonçalves, RC Poulos, Z Cai, S Barthorpe, SS Manda, N Lucas, A Beck, ... Cancer Cell 40 (8), 835-849. e8, 2022 | 94 | 2022 |
| Effects of collection and processing procedures on plasma circulating cell-free DNA from cancer patients B Risberg, DWY Tsui, H Biggs, ARVM de Almagro, SJ Dawson, ... The Journal of Molecular Diagnostics 20 (6), 883-892, 2018 | 93 | 2018 |
| Comprehensive characterization of cell-free tumor DNA in plasma and urine of patients with renal tumors CG Smith, T Moser, F Mouliere, J Field-Rayner, M Eldridge, AL Riediger, ... Genome medicine 12, 1-17, 2020 | 92 | 2020 |
| Fragmentation patterns and personalized sequencing of cell‐free DNA in urine and plasma of glioma patients F Mouliere, CG Smith, K Heider, J Su, Y van der Pol, M Thompson, ... EMBO molecular medicine 13 (8), e12881, 2021 | 80 | 2021 |
| Drug mechanism‐of‐action discovery through the integration of pharmacological and CRISPR screens E Gonçalves, A Segura‐Cabrera, C Pacini, G Picco, FM Behan, P Jaaks, ... Molecular Systems Biology 16 (7), e9405, 2020 | 77 | 2020 |
| Dynamics of multiple resistance mechanisms in plasma DNA during EGFR‐targeted therapies in non‐small cell lung cancer DWY Tsui, M Murtaza, ASC Wong, OM Rueda, CG Smith, ... EMBO molecular medicine 10 (6), e7945, 2018 | 67 | 2018 |
| 1000 Genomes Project Consortium A systematic survey of loss-of-function variants in human protein-coding genes DG MacArthur, S Balasubramanian, A Frankish, N Huang, J Morris, ... Science 335 (6070), 823-828, 2012 | 67 | 2012 |
| Characteristics, origin, and potential for cancer diagnostics of ultrashort plasma cell-free DNA I Hudecova, CG Smith, R Hänsel-Hertsch, CS Chilamakuri, JA Morris, ... Genome research 32 (2), 215-227, 2022 | 52 | 2022 |
| YOGY: a web-based, integrated database to retrieve protein orthologs and associated Gene Ontology terms CJ Penkett, JA Morris, V Wood, J Bähler Nucleic acids research 34 (suppl_2), W330-W334, 2006 | 51 | 2006 |
