Localisation of GPR30, a novel G protein-coupled oestrogen receptor, suggests multiple functions in rodent brain and peripheral tissues GGJ Hazell, ST Yao, JA Roper, ER Prossnitz, AM O'Carroll, SJ Lolait The Journal of endocrinology 202 (2), 223, 2009 | 427 | 2009 |
Emerging therapeutic opportunities for integrin inhibitors RJ Slack, SJF Macdonald, JA Roper, RG Jenkins, RJD Hatley Nature Reviews Drug Discovery 21 (1), 60-78, 2022 | 295 | 2022 |
The vasopressin Avpr1b receptor: molecular and pharmacological studies JA Roper, AM O'carroll, WS Young III, SJ Lolait Stress 14 (1), 98-115, 2011 | 129 | 2011 |
G protein-coupled receptors in the hypothalamic paraventricular and supraoptic nuclei–serpentine gateways to neuroendocrine homeostasis GGJ Hazell, CC Hindmarch, GR Pope, JA Roper, SL Lightman, D Murphy, ... Frontiers in neuroendocrinology 33 (1), 45-66, 2012 | 90 | 2012 |
Syndecan and integrin interactomes: large complexes in small spaces JA Roper, RC Williamson, MD Bass Current opinion in structural biology 22 (5), 583-590, 2012 | 87 | 2012 |
Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis AE John, RH Graves, KT Pun, G Vitulli, EJ Forty, PF Mercer, JL Morrell, ... Nature communications 11 (1), 4659, 2020 | 86 | 2020 |
Pituitary‐adrenal response to acute and repeated mild restraint, forced swim and change in environment stress in arginine vasopressin receptor 1b knockout mice LQ Stewart, JA Roper, WS Young Iii, AM O’Carroll, SJ Lolait Journal of neuroendocrinology 20 (5), 597-605, 2008 | 64 | 2008 |
Attenuated stress response to acute lipopolysaccharide challenge and ethanol administration in vasopressin V1b receptor knockout mice SJ Lolait, LQ Stewart, JA Roper, G Harrison, DS Jessop, WS Young III, ... Journal of neuroendocrinology 19 (7), 543-551, 2007 | 52 | 2007 |
Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure RC Williamson, CAM Cowell, CL Hammond, DJM Bergen, JA Roper, ... Journal of cell science 127 (19), 4292-4307, 2014 | 49 | 2014 |
The role of the arginine vasopressin Avp1b receptor in the acute neuroendocrine action of antidepressants LQ Stewart, JA Roper, WS Young III, AM O’Carroll, SJ Lolait Psychoneuroendocrinology 33 (4), 405-415, 2008 | 49 | 2008 |
Role of nociceptin/orphanin FQ and NOP receptors in the response to acute and repeated restraint stress in rats G Delaney, KL Dawe, R Hogan, T Hunjan, J Roper, G Hazell, SJ Lolait, ... Journal of neuroendocrinology 24 (12), 1527-1541, 2012 | 48 | 2012 |
Ultrasonic stimulation of mouse skin reverses the healing delays in diabetes and aging by activation of Rac1 JA Roper, RC Williamson, B Bally, CAM Cowell, R Brooks, P Stephens, ... Journal of Investigative Dermatology 135 (11), 2842-2851, 2015 | 45 | 2015 |
Discovery and optimization of the first highly effective and orally available galectin-3 inhibitors for treatment of fibrotic disease FR Zetterberg, A MacKinnon, T Brimert, L Gravelle, RE Johnsson, ... Journal of Medicinal Chemistry 65 (19), 12626-12638, 2022 | 41 | 2022 |
Integrins as a drug target in liver fibrosis SR Rahman, JA Roper, JI Grove, GP Aithal, KT Pun, AJ Bennett Liver International 42 (3), 507-521, 2022 | 41 | 2022 |
Attenuated stress response to acute restraint and forced swimming stress in arginine vasopressin 1b receptor subtype (Avpr1b) receptor knockout mice and wild‐type mice treated … JA Roper, M Craighead, AM O’Carroll, SJ Lolait Journal of neuroendocrinology 22 (11), 1173-1180, 2010 | 36 | 2010 |
Chlorhexidine hexametaphosphate as a wound care material coating: antimicrobial efficacy, toxicity and effect on healing ME Barbour, SE Maddocks, HJ Grady, JA Roper, MD Bass, AM Collins, ... Nanomedicine 11 (16), 2049-2057, 2016 | 29 | 2016 |
Induction of adhesion-dependent signals using low-intensity ultrasound J Roper, A Harrison, MD Bass JoVE (Journal of Visualized Experiments), e4024, 2012 | 24 | 2012 |
Coronin-1C protein and caveolin protein provide constitutive and inducible mechanisms of Rac1 protein trafficking RC Williamson, CAM Cowell, T Reville, JA Roper, TCS Rendall, MD Bass Journal of Biological Chemistry 290 (25), 15437-15449, 2015 | 17 | 2015 |
Discovery of selective and orally available galectin-1 inhibitors FR Zetterberg, C Diehl, M Håkansson, B Kahl-Knutson, H Leffler, ... Journal of Medicinal Chemistry 66 (24), 16980-16990, 2023 | 7 | 2023 |
Pharmacological characterisation of GSK3335103, an oral αvβ6 integrin small molecule RGD-mimetic inhibitor for the treatment of fibrotic disease AL Wilkinson, AE John, JW Barrett, E Gower, VS Morrison, Y Man, KT Pun, ... European Journal of Pharmacology 913, 174618, 2021 | 7 | 2021 |