Real-time estimation of biomass and specific growth rate in physiologically variable recombinant fed-batch processes P Wechselberger, P Sagmeister, C Herwig Bioprocess and biosystems engineering 36, 1205-1218, 2013 | 104 | 2013 |
Soft sensor assisted dynamic bioprocess control: Efficient tools for bioprocess development P Sagmeister, P Wechselberger, M Jazini, A Meitz, T Langemann, ... Chemical Engineering Science 96, 190-198, 2013 | 94 | 2013 |
Tunable recombinant protein expression in E. coli: promoter systems and genetic constraints L Marschall, P Sagmeister, C Herwig Applied microbiology and biotechnology 101, 501-512, 2017 | 63 | 2017 |
Tunable recombinant protein expression in E. coli: enabler for continuous processing? L Marschall, P Sagmeister, C Herwig Applied microbiology and biotechnology 100, 5719-5728, 2016 | 44 | 2016 |
Efficient feeding profile optimization for recombinant protein production using physiological information P Wechselberger, P Sagmeister, H Engelking, T Schmidt, J Wenger, ... Bioprocess and biosystems engineering 35, 1637-1649, 2012 | 43 | 2012 |
A novel real‐time method to estimate volumetric mass biodensity based on the combination of dielectric spectroscopy and soft‐sensors D Ehgartner, P Sagmeister, C Herwig, P Wechselberger Journal of Chemical Technology & Biotechnology 90 (2), 262-272, 2015 | 37 | 2015 |
Model‐based analysis on the extractability of information from data in dynamic fed‐batch experiments P Wechselberger, P Sagmeister, C Herwig Biotechnology progress 29 (1), 285-296, 2013 | 32 | 2013 |
Integrated process modeling—a process validation life cycle companion T Zahel, S Hauer, EM Mueller, P Murphy, S Abad, E Vasilieva, D Maurer, ... Bioengineering 4 (4), 86, 2017 | 30 | 2017 |
Information processing: rate-based investigation of cell physiological changes along design space development P Sagmeister, P Wechselberger, C Herwig PDA journal of pharmaceutical science and technology 66 (6), 526-541, 2012 | 28 | 2012 |
A novel method to recover inclusion body protein from recombinant E. coli fed-batch processes based on phage ΦX174-derived lysis protein E D Ehgartner, P Sagmeister, T Langemann, A Meitz, W Lubitz, C Herwig Applied Microbiology and Biotechnology 101, 5603-5614, 2017 | 26 | 2017 |
Tunable recombinant protein expression with E. coli in a mixed-feed environment P Sagmeister, C Schimek, A Meitz, C Herwig, O Spadiut Applied microbiology and biotechnology 98, 2937-2945, 2014 | 26 | 2014 |
Soft-sensor assisted dynamic investigation of mixed feed bioprocesses P Sagmeister, M Kment, P Wechselberger, A Meitz, T Langemann, ... Process Biochemistry 48 (12), 1839-1847, 2013 | 23 | 2013 |
An integrated downstream process development strategy along QbD principles A Meitz, P Sagmeister, T Langemann, C Herwig Bioengineering 1 (4), 213-230, 2014 | 21 | 2014 |
Comparison of data science workflows for root cause analysis of bioprocesses D Borchert, DA Suarez-Zuluaga, P Sagmeister, YE Thomassen, C Herwig Bioprocess and biosystems engineering 42 (2), 245-256, 2019 | 18 | 2019 |
Ex situ online monitoring: application, challenges and opportunities for biopharmaceuticals processes P Kroll, P Sagmeister, W Reichelt, L Neutsch, T Klein, C Herwig Pharmaceutical Bioprocessing 2 (3), 285-300, 2014 | 17 | 2014 |
A dynamic method for the investigation of induced state metabolic capacities as a function of temperature P Sagmeister, T Langemann, P Wechselberger, A Meitz, C Herwig Microbial Cell Factories 12, 1-11, 2013 | 17 | 2013 |
Propagation of measurement accuracy to biomass soft-sensor estimation and control quality V Steinwandter, T Zahel, P Sagmeister, C Herwig Analytical and Bioanalytical Chemistry 409 (3), 693-706, 2017 | 15 | 2017 |
Simple monitoring of cell leakiness and viability in Escherichia coli bioprocesses—A case study DJ Wurm, L Marschall, P Sagmeister, C Herwig, O Spadiut Engineering in Life Sciences 17 (6), 598-604, 2017 | 14 | 2017 |
Fed-batch production of bacterial ghosts using dielectric spectroscopy for dynamic process control A Meitz, P Sagmeister, W Lubitz, C Herwig, T Langemann Microorganisms 4 (2), 18, 2016 | 12 | 2016 |
Workflow for criticality assessment applied in biopharmaceutical process validation stage 1 T Zahel, L Marschall, S Abad, E Vasilieva, D Maurer, EM Mueller, ... Bioengineering 4 (4), 85, 2017 | 11 | 2017 |