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Janet R. Sparrow
Janet R. Sparrow
Anthony Donn Professor, Columbia University Medical Center
Dirección de correo verificada de cumc.columbia.edu
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The lipofuscin fluorophore A2E mediates blue light–induced damage to retinal pigmented epithelial cells
JR Sparrow, K Nakanishi, CA Parish
Investigative ophthalmology & visual science 41 (7), 1981-1989, 2000
7872000
RPE lipofuscin and its role in retinal pathobiology
JR Sparrow, M Boulton
Experimental eye research 80 (5), 595-606, 2005
7842005
Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium
CA Parish, M Hashimoto, K Nakanishi, J Dillon, J Sparrow
Proceedings of the National Academy of Sciences 95 (25), 14609-14613, 1998
5601998
Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium
J Zhou, YP Jang, SR Kim, JR Sparrow
Proceedings of the National Academy of Sciences 103 (44), 16182-16187, 2006
4532006
Involvement of oxidative mechanisms in blue-light-induced damage to A2E-laden RPE
JR Sparrow, J Zhou, S Ben-Shabat, H Vollmer, Y Itagaki, K Nakanishi
Investigative ophthalmology & visual science 43 (4), 1222-1227, 2002
4132002
A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture
JR Sparrow, CA Parish, M Hashimoto, K Nakanishi
Investigative ophthalmology & visual science 40 (12), 2988-2995, 1999
4091999
The bisretinoids of retinal pigment epithelium
JR Sparrow, E Gregory-Roberts, K Yamamoto, A Blonska, SK Ghosh, ...
Progress in retinal and eye research 31 (2), 121-135, 2012
4002012
The susceptibility of the retina to photochemical damage from visible light
JJ Hunter, JIW Morgan, WH Merigan, DH Sliney, JR Sparrow, ...
Progress in retinal and eye research 31 (1), 28-42, 2012
3792012
Blue light–induced apoptosis of A2E-containing RPE: involvement of caspase-3 and protection by Bcl-2
JR Sparrow, B Cai
Investigative ophthalmology & visual science 42 (6), 1356-1362, 2001
3652001
Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice
M Allocca, M Doria, M Petrillo, P Colella, M Garcia-Hoyos, D Gibbs, ...
The Journal of clinical investigation 118 (5), 1955-1964, 2008
3602008
CD36 participates in the phagocytosis of rod outer segments by retinal pigment epithelium
SW Ryeom, JR Sparrow, RL Silverstein
Journal of cell science 109 (2), 387-395, 1996
3091996
Blue light-absorbing intraocular lens and retinal pigment epithelium protection in vitro
JR Sparrow, AS Miller, J Zhou
Journal of Cataract & Refractive Surgery 30 (4), 873-878, 2004
2952004
The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane
J Liu, Y Itagaki, S Ben-Shabat, K Nakanishi, JR Sparrow
Journal of Biological Chemistry 275 (38), 29354-29360, 2000
2952000
SOD2 knockdown mouse model of early AMD
V Justilien, JJ Pang, K Renganathan, X Zhan, JW Crabb, SR Kim, ...
Investigative ophthalmology & visual science 48 (10), 4407-4420, 2007
2792007
Lutein and zeaxanthin supplementation reduces photooxidative damage and modulates the expression of inflammation-related genes in retinal pigment epithelial cells
Q Bian, S Gao, J Zhou, J Qin, A Taylor, EJ Johnson, G Tang, JR Sparrow, ...
Free Radical Biology and Medicine 53 (6), 1298-1307, 2012
2732012
Correction of the disease phenotype in the mouse model of Stargardt disease by lentiviral gene therapy
J Kong, SR Kim, K Binley, I Pata, J Mannik, J Zernant-Rajang, O Kan, ...
Gene therapy 15 (19), 1311-1320, 2008
2662008
Photooxidation of A2-PE, a photoreceptor outer segment fluorophore, and protection by lutein and zeaxanthin
SR Kim, K Nakanishi, Y Itagaki, JR Sparrow
Experimental eye research 82 (5), 828-839, 2006
2652006
Biosynthetic studies of A2E, a major fluorophore of retinal pigment epithelial lipofuscin
S Ben-Shabat, CA Parish, HR Vollmer, Y Itagaki, N Fishkin, K Nakanishi, ...
Journal of Biological Chemistry 277 (9), 7183-7190, 2002
2622002
Quantitative measurements of autofluorescence with the scanning laser ophthalmoscope
F Delori, JP Greenberg, RL Woods, J Fischer, T Duncker, J Sparrow, ...
Investigative ophthalmology & visual science 52 (13), 9379-9390, 2011
2462011
Incomplete retinal pigment epithelial and outer retinal atrophy in age-related macular degeneration: classification of atrophy meeting report 4
RH Guymer, PJ Rosenfeld, CA Curcio, FG Holz, G Staurenghi, KB Freund, ...
Ophthalmology 127 (3), 394-409, 2020
2432020
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
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