| Cytotoxic agents comprising maytansinoids and their therapeutic use RJ Chari, VS Goldmacher, JM Lambert, WA Blattler US Patent 5,208,020, 1993 | 1261 | 1993 |
| Antibody-maytansinoid conjugates are activated in targeted cancer cells by lysosomal degradation and linker-dependent intracellular processing HK Erickson, PU Park, WC Widdison, YV Kovtun, LM Garrett, K Hoffman, ... Cancer research 66 (8), 4426-4433, 2006 | 691 | 2006 |
| A cytomegalovirus-encoded inhibitor of apoptosis that suppresses caspase-8 activation A Skaletskaya, LM Bartle, T Chittenden, AL McCormick, ES Mocarski, ... Proceedings of the National Academy of Sciences 98 (14), 7829-7834, 2001 | 564 | 2001 |
| A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2 VS Goldmacher, LM Bartle, A Skaletskaya, CA Dionne, NL Kedersha, ... Proceedings of the National Academy of Sciences 96 (22), 12536-12541, 1999 | 555 | 1999 |
| Humanization of murine monoclonal antibodies through variable domain resurfacing. MA Roguska, JT Pedersen, CA Keddy, AH Henry, SJ Searle, JM Lambert, ... Proceedings of the National Academy of Sciences 91 (3), 969-973, 1994 | 517 | 1994 |
| Antibody-drug conjugates designed to eradicate tumors with homogeneous and heterogeneous expression of the target antigen YV Kovtun, CA Audette, Y Ye, H Xie, MF Ruberti, SJ Phinney, BA Leece, ... Cancer research 66 (6), 3214-3221, 2006 | 496 | 2006 |
| Immunoconjugates containing novel maytansinoids: promising anticancer drugs RVJ Chari, BA Martell, JL Gross, SB Cook, SA Shah, WA Blättler, ... Cancer research 52 (1), 127-131, 1992 | 478 | 1992 |
| Semisynthetic maytansine analogues for the targeted treatment of cancer WC Widdison, SD Wilhelm, EE Cavanagh, KR Whiteman, BA Leece, ... Journal of medicinal chemistry 49 (14), 4392-4408, 2006 | 477 | 2006 |
| SAR650984, A Novel Humanized CD38-Targeting Antibody, Demonstrates Potent Antitumor Activity in Models of Multiple Myeloma and Other CD38+ Hematologic … J Deckert, MC Wetzel, LM Bartle, A Skaletskaya, VS Goldmacher, F Vallée, ... Clinical Cancer Research 20 (17), 4574-4583, 2014 | 362 | 2014 |
| Eradication of large colon tumor xenografts by targeted delivery of maytansinoids. C Liu, BM Tadayoni, LA Bourret, KM Mattocks, SM Derr, WC Widdison, ... Proceedings of the National Academy of Sciences 93 (16), 8618-8623, 1996 | 327 | 1996 |
| The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal HLA Vieira, AS Belzacq, D Haouzi, F Bernassola, I Cohen, E Jacotot, ... Oncogene 20 (32), 4305-4316, 2001 | 307 | 2001 |
| Antibody-maytansinoid conjugates designed to bypass multidrug resistance YV Kovtun, CA Audette, MF Mayo, GE Jones, H Doherty, EK Maloney, ... Cancer research 70 (6), 2528-2537, 2010 | 304 | 2010 |
| Cell killing by antibody–drug conjugates YV Kovtun, VS Goldmacher Cancer letters 255 (2), 232-240, 2007 | 280 | 2007 |
| Cytomegalovirus cell death suppressor vMIA blocks Bax-but not Bak-mediated apoptosis by binding and sequestering Bax at mitochondria D Arnoult, LM Bartle, A Skaletskaya, D Poncet, N Zamzami, PU Park, ... Proceedings of the National Academy of Sciences 101 (21), 7988-7993, 2004 | 261 | 2004 |
| Serotherapy of B-cell neoplasms with anti-B4-blocked ricin: a phase I trial of daily bolus infusion ML Grossbard, AS Freedman, J Ritz, F Coral, VS Goldmacher, L Eliseo, ... | 244 | 1992 |
| Isolation and partial characterization of human cell mutants differing in sensitivity to killing and mutation by methylnitrosourea and N-methyl-N'-nitro-N-nitrosoguanidine. VS Goldmacher, RA Cuzick Jr, WG Thilly Journal of Biological Chemistry 261 (27), 12462-12471, 1986 | 244 | 1986 |
| Synthesis and evaluation of hydrophilic linkers for antibody–maytansinoid conjugates RY Zhao, SD Wilhelm, C Audette, G Jones, BA Leece, AC Lazar, ... Journal of medicinal chemistry 54 (10), 3606-3623, 2011 | 241 | 2011 |
| Anti-B4-blocked ricin: a phase I trial of 7-day continuous infusion in patients with B-cell neoplasms. ML Grossbard, JM Lambert, VS Goldmacher, NL Spector, J Kinsella, ... Journal of clinical oncology 11 (4), 726-737, 1993 | 232 | 1993 |
| Purified immunotoxins that are reactive with human lymphoid cells. Monoclonal antibodies conjugated to the ribosome-inactivating proteins gelonin and the pokeweed antiviral … JM Lambert, PD Senter, A Yau-Young, WA Blättler, VS Goldmacher Journal of Biological Chemistry 260 (22), 12035-12041, 1985 | 209 | 1985 |
| IMGN853, a folate receptor-α (FRα)–targeting antibody–drug conjugate, exhibits potent targeted antitumor activity against FRα-expressing tumors O Ab, KR Whiteman, LM Bartle, X Sun, R Singh, D Tavares, A LaBelle, ... Molecular cancer therapeutics 14 (7), 1605-1613, 2015 | 201 | 2015 |
