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Hannes Ausserwöger
Hannes Ausserwöger
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Non-specificity as the sticky problem in therapeutic antibody development
H Ausserwöger, MM Schneider, TW Herling, P Arosio, G Invernizzi, ...
Nature Reviews Chemistry 6 (12), 844-861, 2022
402022
Spatially non-uniform condensates emerge from dynamically arrested phase separation
NA Erkamp, T Sneideris, H Ausserwöger, D Qian, S Qamar, J Nixon-Abell, ...
Nature Communications 14 (1), 684, 2023
37*2023
Sequence-based prediction of pH-dependent protein solubility using CamSol
M Oeller, R Kang, R Bell, H Ausserwöger, P Sormanni, M Vendruscolo
Briefings in Bioinformatics 24 (2), bbad004, 2023
242023
Surface patches induce nonspecific binding and phase separation of antibodies
H Ausserwöger, G Krainer, TJ Welsh, N Thorsteinson, E de Csilléry, ...
Proceedings of the National Academy of Sciences 120 (15), e2210332120, 2023
13*2023
Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates
NA Erkamp, M Farag, Y Qiu, D Qian, T Sneideris, T Wu, TJ Welsh, ...
bioRxiv, 2024.08. 19.608662, 2024
9*2024
Targeting nucleic acid phase transitions as a mechanism of action for antimicrobial peptides
T Sneideris, NA Erkamp, H Ausserwöger, KL Saar, TJ Welsh, D Qian, ...
Nature Communications 14 (1), 7170, 2023
9*2023
Solutes unmask differences in clustering versus phase separation of FET proteins
M Kar, LT Vogel, G Chauhan, S Felekyan, H Ausserwöger, TJ Welsh, ...
Nature communications 15 (1), 4408, 2024
8*2024
Quantifying collective interactions in biomolecular phase separation
H Ausserwöger, D Qian, G Krainer, E de Csilléry, TJ Welsh, T Sneideris, ...
bioRxiv 31 (2023), 10.1101, 2023
6*2023
Minimizing Material Consumption in Flow Process Research and Development: A Novel Approach Toward Robust and Controlled Mixing of Reactants
J Haber, H Ausserwoeger, C Lehmann, L Pillet, B Schenkel, B Guelat
Organic Process Research & Development 26 (8), 2456-2463, 2022
62022
Dominance analysis to assess solute contributions to multicomponent phase equilibria
D Qian, H Ausserwoger, T Sneideris, M Farag, RV Pappu, TPJ Knowles
Proceedings of the National Academy of Sciences 121 (33), e2407453121, 2024
4*2024
Multidimensional protein solubility optimization with an ultrahigh-throughput microfluidic platform
NA Erkamp, M Oeller, T Sneideris, H Ausserwoger, A Levin, TJ Welsh, ...
Analytical Chemistry 95 (12), 5362-5368, 2023
42023
De novo human angiotensin-converting enzyme 2 decoy NL-CVX1 protects mice from severe disease after severe acute respiratory syndrome coronavirus 2 infection
M Rebelo, C Tang, AR Coelho, C Labão-Almeida, MM Schneider, ...
The Journal of infectious diseases 228 (6), 723-733, 2023
22023
Single-molecule digital sizing of proteins in solution
G Krainer, RPB Jacquat, MM Schneider, TJ Welsh, J Fan, QAE Peter, ...
Nature Communications 15 (1), 7740, 2024
12024
Nonspecificity fingerprints for clinical-stage antibodies in solution
TW Herling, G Invernizzi, H Ausserwöger, JR Bjelke, T Egebjerg, S Lund, ...
Proceedings of the National Academy of Sciences 120 (52), e2306700120, 2023
12023
Linking modulation of bio-molecular phase behaviour with collective interactions
D Qian, H Ausserwoger, WE Arter, R Scrutton, TJ Welsh, T Kartanas, ...
bioRxiv, 2023.11. 02.565376, 2023
12023
Driving forces for condensation of synapsin are governed by sequence-encoded molecular grammars
C Hoffmann, KM Ruff, I Edu, M Kyung Shinn, J Tromm, M King, A Pant, ...
bioRxiv, 2024.08. 03.606464, 2024
2024
Biomolecular condensates sustain pH gradients at equilibrium driven by charge neutralisation
H Ausserwoeger, RM Scrutton, T Sneideris, CM Fischer, D Qian, ...
bioRxiv, 2024.05. 23.595321, 2024
2024
Temperature-induced changes in protein interactions control RNA recruitment to G3BP1 condensates
CM Fischer, H Ausserwoger, T Sneideris, D Qian, R Scrutton, S Qamar, ...
bioRxiv, 2024.02. 02.578543, 2024
2024
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