| Metabotropic glutamate receptors: physiology, pharmacology, and disease CM Niswender, PJ Conn Annual review of pharmacology and toxicology 50 (1), 295-322, 2010 | 2228 | 2010 |
| Regulation of serotonin-2C receptor G-protein coupling by RNA editing CM Burns, H Chu, SM Rueter, LK Hutchinson, H Canton, E Sanders-Bush, ... Nature 387 (6630), 303-308, 1997 | 1232 | 1997 |
| Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator H Wu, C Wang, KJ Gregory, GW Han, HP Cho, Y Xia, CM Niswender, ... Science 344 (6179), 58-64, 2014 | 603 | 2014 |
| RNA editing of the human serotonin 5-hydroxytryptamine 2C receptor silences constitutive activity CM Niswender, SC Copeland, K Herrick-Davis, RB Emeson, ... Journal of Biological Chemistry 274 (14), 9472-9478, 1999 | 447 | 1999 |
| Glutamate receptors as therapeutic targets for Parkinson's disease KA Johnson, PJ Conn, CM Niswender CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2009 | 319 | 2009 |
| RNA editing of the human serotonin 5-HT2C receptor: alterations in suicide and implications for serotonergic pharmacotherapy CM Niswender, K Herrick-Davis, GE Dilley, HY Meltzer, JC Overholser, ... Neuropsychopharmacology 24 (5), 478-491, 2001 | 312 | 2001 |
| Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders PJ Conn, CW Lindsley, J Meiler, CM Niswender Nature reviews Drug discovery 13 (9), 692-708, 2014 | 283 | 2014 |
| Allosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discovery BJ Melancon, CR Hopkins, MR Wood, KA Emmitte, CM Niswender, ... Journal of medicinal chemistry 55 (4), 1445-1464, 2012 | 257 | 2012 |
| Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4 CM Niswender, KA Johnson, CD Weaver, CK Jones, Z Xiang, Q Luo, ... Molecular pharmacology 74 (5), 1345-1358, 2008 | 238 | 2008 |
| Serotonin 5‐HT2C Receptor RNA Editing Alters Receptor Basal Activity: Implications for Serotonergic Signal Transduction K Herrick‐Davis, E Grinde, CM Niswender Journal of neurochemistry 73 (4), 1711-1717, 1999 | 227 | 1999 |
| Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of … AL Rodriguez, MD Grier, CK Jones, EJ Herman, AS Kane, RL Smith, ... Molecular pharmacology 78 (6), 1105-1123, 2010 | 210 | 2010 |
| Glutamate receptor RNA editing in vitro by enzymatic conversion of adenosine to inosine SM Rueter, CM Burns, SA Coode, P Mookherjee, RB Emeson Science 267 (5203), 1491-1494, 1995 | 201 | 1995 |
| Practical strategies and concepts in GPCR allosteric modulator discovery: recent advances with metabotropic glutamate receptors CW Lindsley, KA Emmitte, CR Hopkins, TM Bridges, KJ Gregory, ... Chemical reviews 116 (11), 6707-6741, 2016 | 181 | 2016 |
| An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission JK Shirey, Z Xiang, D Orton, AE Brady, KA Johnson, R Williams, JE Ayala, ... Nature chemical biology 4 (1), 42-50, 2008 | 180 | 2008 |
| RNA‐editing of the 5‐HT2C receptor alters agonist‐receptor‐effector coupling specificity KA Berg, JD Cropper, CM Niswender, E Sanders‐Bush, RB Emeson, ... British journal of pharmacology 134 (2), 386-392, 2001 | 177 | 2001 |
| Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity JE Marlo, CM Niswender, EL Days, TM Bridges, Y Xiang, AL Rodriguez, ... Molecular pharmacology 75 (3), 577-588, 2009 | 171 | 2009 |
| ML297 (VU0456810), the first potent and selective activator of the GIRK potassium channel, displays antiepileptic properties in mice K Kaufmann, I Romaine, E Days, C Pascual, A Malik, L Yang, B Zou, Y Du, ... ACS chemical neuroscience 4 (9), 1278-1286, 2013 | 165 | 2013 |
| A novel selective muscarinic acetylcholine receptor subtype 1 antagonist reduces seizures without impairing hippocampus-dependent learning DJ Sheffler, R Williams, TM Bridges, Z Xiang, AS Kane, NE Byun, ... Molecular pharmacology 76 (2), 356-368, 2009 | 142 | 2009 |
| Selective Activation of M4 Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents M Bubser, TM Bridges, D Dencker, RW Gould, M Grannan, MJ Noetzel, ... ACS chemical neuroscience 5 (10), 920-942, 2014 | 139 | 2014 |
| Antipsychotic-like effects of M4 positive allosteric modulators are mediated by CB2 receptor-dependent inhibition of dopamine release DJ Foster, JM Wilson, DH Remke, MS Mahmood, MJ Uddin, J Wess, ... Neuron 91 (6), 1244-1252, 2016 | 136 | 2016 |
