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Michael W. Becker
Michael W. Becker
Independent
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Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
I Park, D Qian, M Kiel, MW Becker, M Pihalja, IL Weissman, SJ Morrison, ...
Nature 423 (6937), 302-305, 2003
23962003
BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells
ED Lagadinou, A Sach, K Callahan, RM Rossi, SJ Neering, ...
Cell stem cell 12 (3), 329-341, 2013
12802013
Therapeutic implications of cancer stem cells
M Al-Hajj, MW Becker, M Wicha, I Weissman, MF Clarke
Current opinion in genetics & development 14 (1), 43-47, 2004
7912004
An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells
ML Guzman, RM Rossi, S Neelakantan, X Li, CA Corbett, DC Hassane, ...
Blood, The Journal of the American Society of Hematology 110 (13), 4427-4435, 2007
5182007
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia
S Li, FE Garrett-Bakelman, SS Chung, MA Sanders, T Hricik, F Rapaport, ...
Nature medicine 22 (7), 792-799, 2016
3952016
Dysregulated gene expression networks in human acute myelogenous leukemia stem cells
R Majeti, MW Becker, Q Tian, TLM Lee, X Yan, R Liu, JH Chiang, L Hood, ...
Proceedings of the National Academy of Sciences 106 (9), 3396-3401, 2009
3592009
Mutation in the SPINK1 trypsin inhibitor gene, alcohol use, and chronic pancreatitis
H Witt, W Luck, M Becker, M Böhmig, A Kage, K Truninger, RW Ammann, ...
Jama 285 (21), 2716-2717, 2001
2602001
FDA-approved ferumoxytol displays anti-leukaemia efficacy against cells with low ferroportin levels
V Trujillo-Alonso, EC Pratt, H Zong, A Lara-Martinez, C Kaittanis, ...
Nature nanotechnology 14 (6), 616-622, 2019
2422019
Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia
BJ Frisch, JM Ashton, L Xing, MW Becker, CT Jordan, LM Calvi
Blood, The Journal of the American Society of Hematology 119 (2), 540-550, 2012
2392012
Evolution of acute myelogenous leukemia stem cell properties after treatment and progression
TC Ho, M LaMere, BM Stevens, JM Ashton, JR Myers, KM O’Dwyer, ...
Blood, The Journal of the American Society of Hematology 128 (13), 1671-1678, 2016
2372016
Chromosome 5q deletion and epigenetic suppression of the gene encoding α-catenin (CTNNA1) in myeloid cell transformation
TX Liu, MW Becker, J Jelinek, WS Wu, M Deng, N Mikhalkevich, K Hsu, ...
Nature medicine 13 (1), 78-83, 2007
2372007
Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells
S Pei, M Minhajuddin, KP Callahan, M Balys, JM Ashton, SJ Neering, ...
Journal of Biological Chemistry 288 (47), 33542-33558, 2013
2262013
Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells
BM Stevens, CL Jones, DA Pollyea, R Culp-Hill, A D’Alessandro, ...
Nature cancer 1 (12), 1176-1187, 2020
2082020
The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation
HA Zahreddine, B Culjkovic-Kraljacic, S Assouline, P Gendron, ...
Nature 511 (7507), 90-93, 2014
2022014
Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors
OO Akala, IK Park, D Qian, M Pihalja, MW Becker, MF Clarke
Nature 453 (7192), 228-232, 2008
1982008
Chemotherapy induces senescence-like resilient cells capable of initiating AML recurrence
C Duy, M Li, M Teater, C Meydan, FE Garrett-Bakelman, TC Lee, CR Chin, ...
Cancer discovery 11 (6), 1542-1561, 2021
1742021
Nicotinamide metabolism mediates resistance to venetoclax in relapsed acute myeloid leukemia stem cells
CL Jones, BM Stevens, DA Pollyea, R Culp-Hill, JA Reisz, T Nemkov, ...
Cell stem cell 27 (5), 748-764. e4, 2020
1682020
Dissociation of the contractile and hypertrophic effects of vasoconstrictor prostanoids in vascular smooth muscle.
GW Dorn 2nd, MW Becker, MG Davis
Journal of Biological Chemistry 267 (34), 24897-24905, 1992
1421992
Prostaglandin E2 increases hematopoietic stem cell survival and accelerates hematopoietic recovery after radiation injury
RL Porter, MA Georger, O Bromberg, KE McGrath, BJ Frisch, MW Becker, ...
Stem cells 31 (2), 372-383, 2013
1282013
Aged marrow macrophages expand platelet-biased hematopoietic stem cells via interleukin-1B
BJ Frisch, CM Hoffman, SE Latchney, MW LaMere, J Myers, J Ashton, ...
JCI insight 4 (10), 2019
1222019
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