T-helper type 2–driven inflammation defines major subphenotypes of asthma PG Woodruff, B Modrek, DF Choy, G Jia, AR Abbas, A Ellwanger, ... American journal of respiratory and critical care medicine 180 (5), 388-395, 2009 | 2018 | 2009 |
Azithromycin for prevention of exacerbations of COPD RK Albert, J Connett, WC Bailey, R Casaburi, JAD Cooper Jr, GJ Criner, ... New England Journal of Medicine 365 (8), 689-698, 2011 | 1568 | 2011 |
Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids PG Woodruff, HA Boushey, GM Dolganov, CS Barker, YH Yang, ... Proceedings of the National Academy of Sciences 104 (40), 15858-15863, 2007 | 930 | 2007 |
Muc5b is required for airway defence MG Roy, A Livraghi-Butrico, AA Fletcher, MM McElwee, SE Evans, ... Nature 505 (7483), 412-416, 2014 | 780 | 2014 |
Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients G Jia, RW Erickson, DF Choy, S Mosesova, LC Wu, OD Solberg, ... Journal of Allergy and Clinical Immunology 130 (3), 647-654. e10, 2012 | 744 | 2012 |
Clinical significance of symptoms in smokers with preserved pulmonary function PG Woodruff, RG Barr, E Bleecker, SA Christenson, D Couper, JL Curtis, ... New England Journal of Medicine 374 (19), 1811-1821, 2016 | 720 | 2016 |
COVID-19–related genes in sputum cells in asthma. Relationship to demographic features and corticosteroids MC Peters, S Sajuthi, P Deford, S Christenson, CL Rios, MT Montgomery, ... American journal of respiratory and critical care medicine 202 (1), 83-90, 2020 | 543 | 2020 |
Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression PG Woodruff, GM Dolganov, RE Ferrando, S Donnelly, SR Hays, ... American journal of respiratory and critical care medicine 169 (9), 1001-1006, 2004 | 520 | 2004 |
Roles of epithelial cell-derived periostin in TGF-β activation, collagen production, and collagen gel elasticity in asthma SS Sidhu, S Yuan, AL Innes, S Kerr, PG Woodruff, L Hou, SJ Muller, ... Proceedings of the national academy of sciences 107 (32), 14170-14175, 2010 | 486 | 2010 |
Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts MC Peters, KW McGrath, GA Hawkins, AT Hastie, BD Levy, E Israel, ... The Lancet Respiratory Medicine 4 (7), 574-584, 2016 | 455 | 2016 |
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction EM Dunican, BM Elicker, DS Gierada, SK Nagle, ML Schiebler, JD Newell, ... The Journal of clinical investigation 128 (3), 997-1009, 2018 | 448 | 2018 |
Inflammatory and comorbid features of patients with severe asthma and frequent exacerbations LC Denlinger, BR Phillips, S Ramratnam, K Ross, NR Bhakta, JC Cardet, ... American journal of respiratory and critical care medicine 195 (3), 302-313, 2017 | 433 | 2017 |
Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma MC Peters, ZK Mekonnen, S Yuan, NR Bhakta, PG Woodruff, JV Fahy Journal of Allergy and Clinical Immunology 133 (2), 388-394. e5, 2014 | 423 | 2014 |
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries N Shrine, AL Guyatt, AM Erzurumluoglu, VE Jackson, BD Hobbs, ... Nature genetics 51 (3), 481-493, 2019 | 410 | 2019 |
Simvastatin for the prevention of exacerbations in moderate-to-severe COPD GJ Criner, JE Connett, SD Aaron, RK Albert, WC Bailey, R Casaburi, ... New England Journal of Medicine 370 (23), 2201-2210, 2014 | 390 | 2014 |
Design of the subpopulations and intermediate outcomes in COPD study (SPIROMICS) D Couper, LM LaVange, ML Han, RG Barr, E Bleecker, EA Hoffman, ... Thorax 69 (5), 492-495, 2014 | 389 | 2014 |
Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis BD Hobbs, K De Jong, M Lamontagne, Y Bossé, N Shrine, MS Artigas, ... Nature genetics 49 (3), 426-432, 2017 | 381 | 2017 |
Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction F Huang, H Zhang, M Wu, H Yang, M Kudo, CJ Peters, PG Woodruff, ... Proceedings of the National Academy of Sciences 109 (40), 16354-16359, 2012 | 367 | 2012 |
Airway mucin concentration as a marker of chronic bronchitis M Kesimer, AA Ford, A Ceppe, G Radicioni, R Cao, CW Davis, ... New England Journal of Medicine 377 (10), 911-922, 2017 | 354 | 2017 |
Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients B Levänen, NR Bhakta, PT Paredes, R Barbeau, S Hiltbrunner, JL Pollack, ... Journal of Allergy and Clinical Immunology 131 (3), 894-903. e8, 2013 | 353 | 2013 |