A genome-scale shRNA resource for transgenic RNAi in Drosophila JQ Ni, R Zhou, B Czech, LP Liu, L Holderbaum, D Yang-Zhou, HS Shim, ... Nature methods 8 (5), 405-407, 2011 | 866 | 2011 |
The rhino-deadlock-cutoff complex licenses noncanonical transcription of dual-strand piRNA clusters in Drosophila F Mohn, G Sienski, D Handler, J Brennecke Cell 157 (6), 1364-1379, 2014 | 396 | 2014 |
piRNA-guided slicing specifies transcripts for Zucchini-dependent, phased piRNA biogenesis F Mohn, D Handler, J Brennecke Science 348 (6236), 812-817, 2015 | 368 | 2015 |
The genetic makeup of the Drosophila piRNA pathway D Handler, K Meixner, M Pizka, K Lauss, C Schmied, FS Gruber, ... Molecular cell 50 (5), 762-777, 2013 | 235 | 2013 |
A systematic analysis of Drosophila TUDOR domain‐containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors D Handler, D Olivieri, M Novatchkova, FS Gruber, K Meixner, K Mechtler, ... The EMBO journal 30 (19), 3977-3993, 2011 | 212 | 2011 |
Genetic and mechanistic diversity of piRNA 3′-end formation R Hayashi, J Schnabl, D Handler, F Mohn, SL Ameres, J Brennecke Nature 539 (7630), 588-592, 2016 | 139 | 2016 |
The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation J Batki, J Schnabl, J Wang, D Handler, VI Andreev, CE Stieger, ... Nature structural & molecular biology 26 (8), 720-731, 2019 | 92 | 2019 |
The exon junction complex is required for definition and excision of neighboring introns in Drosophila R Hayashi, D Handler, D Ish-Horowicz, J Brennecke Genes & development 28 (16), 1772-1785, 2014 | 68 | 2014 |
The Drosophila ZAD zinc finger protein Kipferl guides Rhino to piRNA clusters L Baumgartner, D Handler, SW Platzer, C Yu, P Duchek, J Brennecke Elife 11, e80067, 2022 | 36 | 2022 |
A universal method for the rapid isolation of all known classes of functional silencing small RNAs T Grentzinger, S Oberlin, G Schott, D Handler, J Svozil, ... Nucleic acids research 48 (14), e79-e79, 2020 | 30 | 2020 |
Pitfalls of mapping high-throughput sequencing data to repetitive sequences: Piwi’s genomic targets still not identified GK Marinov, J Wang, D Handler, BJ Wold, Z Weng, GJ Hannon, AA Aravin, ... Developmental Cell 32 (6), 765-771, 2015 | 27 | 2015 |
Panoramix SUMOylation on chromatin connects the piRNA pathway to the cellular heterochromatin machinery VI Andreev, C Yu, J Wang, J Schnabl, L Tirian, M Gehre, D Handler, ... Nature Structural & Molecular Biology 29 (2), 130-142, 2022 | 22 | 2022 |
Head-to-head comparison of direct-input RT-PCR and RT-LAMP against RT-qPCR on extracted RNA for rapid SARS-CoV-2 diagnostics MJ Kellner, M Matl, JJ Ross, J Schnabl, D Handler, R Heinen, J Schaeffer, ... MedRxiv, 2021.01. 19.21250079, 2021 | 11 | 2021 |
A conserved fertilization complex of Izumo1, Spaca6, and Tmem81 mediates sperm-egg interaction in vertebrates VE Deneke, A Blaha, Y Lu, JM Draper, CS Phan, K Panser, A Schleiffer, ... BioRxiv, 2023.07. 27.550750, 2023 | 7 | 2023 |
Spatially resolved proteomics of the Arabidopsis stomatal lineage identifies polarity complexes for cell divisions and stomatal pores ES Wallner, A Mair, D Handler, C McWhite, SL Xu, L Dolan, ... Developmental Cell 59 (9), 1096-1109. e5, 2024 | 6 | 2024 |
Functional Adaptations of Endogenous Retroviruses to the Drosophila Host Underlie their Evolutionary Diversification KA Senti, D Handler, B Rafanel, C Kosiol, C Schloetterer, J Brennecke bioRxiv, 2023.08. 03.551782, 2023 | 4 | 2023 |
Selfish conflict underlies RNA-mediated parent-of-origin effects P Pliota, H Marvanova, A Koreshova, Y Kaufman, P Tikanova, D Krogull, ... Nature 628 (8006), 122-129, 2024 | 3 | 2024 |
Evolutionary adaptation of the chromodomain of the HP1-protein Rhino allows the integration of chromatin and DNA sequence signals L Baumgartner, JJ Ipsaro, U Hohmann, D Handler, A Schleiffer, P Duchek, ... eLife 13, 2024 | 1 | 2024 |
Evolutionary adaptation of an HP1-protein chromodomain integrates chromatin and DNA sequence signals L Baumgartner, JJ Ipsaro, U Hohmann, D Handler, A Schleiffer, P Duchek, ... Elife 13, RP93194, 2024 | | 2024 |
A molecular switch orchestrates the nuclear export of human messenger RNA U Hohmann, M Graf, U Schellhaas, B Pacheco-Fiallos, L Fin, ... bioRxiv, 2024.03. 24.586400, 2024 | | 2024 |