Artikkelit, joihin on yleisen käytön mandaatti - Roger L WilliamsLisätietoja
Ei saatavilla missään: 6
Arvostele
Synergy in activating class I PI3Ks
JE Burke, RL Williams
Trends in biochemical sciences 40 (2), 88-100, 2015
Mandaatit: British Heart Foundation, UK Medical Research Council
Arvostele
PIKKs—the solenoid nest where partners and kinases meet
D Baretić, RL Williams
Current opinion in structural biology 29, 134-142, 2014
Mandaatit: UK Medical Research Council
Arvostele
The structural basis for mTOR function
D Baretić, RL Williams
Seminars in cell & developmental biology 36, 91-101, 2014
Mandaatit: UK Medical Research Council
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A class of highly selective inhibitors bind to an active state of PI3Kγ
G Gangadhara, G Dahl, T Bohnacker, R Rae, J Gunnarsson, S Blaho, ...
Nature chemical biology 15 (4), 348-357, 2019
Mandaatit: Swiss National Science Foundation, UK Medical Research Council
Arvostele
Structural insights into the critical DNA damage sensors DNA-PKcs, ATM and ATR
D Baretic, TM de Oliveira, M Niess, P Wan, H Pollard, CM Johnson, ...
Progress in biophysics and molecular biology 147, 4-16, 2019
Mandaatit: UK Medical Research Council
Arvostele
Methods in the study of PTEN structure: x-ray crystallography and hydrogen deuterium exchange mass spectrometry
GR Masson, JE Burke, RL Williams
PTEN: Methods and Protocols, 215-230, 2016
Mandaatit: UK Medical Research Council
Saatavilla jossain: 67
Arvostele
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Mandaatit: Swiss National Science Foundation, US National Institutes of Health, US …
Arvostele
Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage
I Angulo, O Vadas, F Garçon, E Banham-Hall, V Plagnol, TR Leahy, ...
Science 342 (6160), 866-871, 2013
Mandaatit: Swiss National Science Foundation, US National Institutes of Health …
Arvostele
Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases
B Apsel, JA Blair, B Gonzalez, TM Nazif, ME Feldman, B Aizenstein, ...
Nature chemical biology 4 (11), 691, 2008
Mandaatit: US National Institutes of Health, Howard Hughes Medical Institute
Arvostele
The p110δ structure: mechanisms for selectivity and potency of new PI (3) K inhibitors
A Berndt, S Miller, O Williams, DD Le, BT Houseman, JI Pacold, F Gorrec, ...
Nature chemical biology 6 (2), 117-124, 2010
Mandaatit: US National Institutes of Health
Arvostele
Structural basis for activation and inhibition of class I phosphoinositide 3-kinases
O Vadas, JE Burke, X Zhang, A Berndt, RL Williams
Science signaling 4 (195), re2-re2, 2011
Mandaatit: Swiss National Science Foundation
Arvostele
Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA)
JE Burke, O Perisic, GR Masson, O Vadas, RL Williams
Proceedings of the National Academy of Sciences 109 (38), 15259-15264, 2012
Mandaatit: Swiss National Science Foundation, British Heart Foundation
Arvostele
Shaping development of autophagy inhibitors with the structure of the lipid kinase Vps34
S Miller, B Tavshanjian, A Oleksy, O Perisic, BT Houseman, KM Shokat, ...
Science 327 (5973), 1638, 2010
Mandaatit: Howard Hughes Medical Institute
Arvostele
The cargo receptor NDP52 initiates selective autophagy by recruiting the ULK complex to cytosol-invading bacteria
BJ Ravenhill, KB Boyle, N von Muhlinen, CJ Ellison, GR Masson, ...
Molecular cell 74 (2), 320-329. e6, 2019
Mandaatit: UK Medical Research Council, Wellcome Trust
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Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes
K Rostislavleva, N Soler, Y Ohashi, L Zhang, E Pardon, JE Burke, ...
Science 350 (6257), aac7365, 2015
Mandaatit: Research Foundation (Flanders), UK Biotechnology and Biological Sciences …
Arvostele
Structure of lipid kinase p110β/p85β elucidates an unusual SH2-domain-mediated inhibitory mechanism
X Zhang, O Vadas, O Perisic, KE Anderson, J Clark, PT Hawkins, ...
Molecular cell 41 (5), 567-578, 2011
Mandaatit: Swiss National Science Foundation
Arvostele
Activation of GCN2 by the ribosomal P-stalk
AJ Inglis, GR Masson, S Shao, O Perisic, SH McLaughlin, RS Hegde, ...
Proceedings of the National Academy of Sciences 116 (11), 4946-4954, 2019
Mandaatit: UK Medical Research Council
Arvostele
G protein–coupled receptor–mediated activation of p110β by Gβγ is required for cellular transformation and invasiveness
HA Dbouk, O Vadas, A Shymanets, JE Burke, RS Salamon, BD Khalil, ...
Science signaling 5 (253), ra89-ra89, 2012
Mandaatit: Swiss National Science Foundation, US National Institutes of Health, German …
Arvostele
Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi
G D’Angelo, T Uemura, CC Chuang, E Polishchuk, M Santoro, ...
Nature 501 (7465), 116-120, 2013
Mandaatit: Fondazione Telethon, Italy, British Heart Foundation, UK Medical Research …
Arvostele
Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24
S Ghazi-Tabatabai, S Saksena, JM Short, AV Pobbati, DB Veprintsev, ...
Structure 16 (9), 1345-1356, 2008
Mandaatit: US National Institutes of Health
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